scholarly journals Bortezomib effectiveness in one patient with acquired von Willebrand syndrome associated to monoclonal gammopathy of undetermined significance

2010 ◽  
pp. NA-NA ◽  
Author(s):  
Mario Ojeda-Uribe ◽  
Claudine Caron ◽  
Nathalie Itzhar-Baikian ◽  
Agathe Debliquis
2019 ◽  
Vol 39 (04) ◽  
pp. 409-412
Author(s):  
Stéphanie Désage ◽  
Sandra Le Quellec ◽  
Lionel Karlin ◽  
Anne Lienhart ◽  
Sandrine Meunier ◽  
...  

AbstractAcquired von Willebrand syndrome (AVWS) is a rare bleeding disorder. We report herein a case of AVWS due to a monoclonal gammopathy of undetermined significance, in which a transient but prolonged response to a treatment by intravenous immunoglobulin (IVIG) was observed. The diagnosis was fortuitously made in a preoperative setting for neurosurgery, after biological exploration of an isolated prolonged activated partial thromboplastin time. AVWS was confirmed by an accelerated clearance of an infused plasma-derived von Willebrand factor (VWF) concentrate. High doses of IVIG were used to perform the neurosurgery. Fifty-four days after IVIG, the patient was still responding to treatment with normal levels of factor VIII and VWF.


2013 ◽  
Vol 93 (8) ◽  
pp. 1427-1428
Author(s):  
Toshiaki Yujiri ◽  
Yukinori Nakamura ◽  
Isamu Oota ◽  
Kaori Nakano ◽  
Yukio Tanizawa

2008 ◽  
Vol 99 (04) ◽  
pp. 782-783 ◽  
Author(s):  
David Grimaldi ◽  
Pablo Bartolucci ◽  
Michele Gouault-Heilmann ◽  
Isabelle Martin-Toutain ◽  
Mehdi Khellaf ◽  
...  

2010 ◽  
Vol 30 (S 01) ◽  
pp. S177-S178
Author(s):  
P. Lages ◽  
R. Zimmermann ◽  
A. Huth-Kühne ◽  
P. Staritz

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