scholarly journals Aggressive T-cell large granular lymphocyte leukemia: A case report and review of the literature

2007 ◽  
Vol 82 (6) ◽  
pp. 481-485 ◽  
Author(s):  
Todd J. Alekshun ◽  
Jianguo Tao ◽  
Lubomir Sokol
2009 ◽  
Vol 48 (16) ◽  
pp. 1443-1447 ◽  
Author(s):  
Koji Miyazaki ◽  
Manabu Ohsaka ◽  
Yuhko Suzuki ◽  
Mikio Danbara ◽  
Ryouichi Horie ◽  
...  

2016 ◽  
Vol 69 (11-12) ◽  
pp. 376-378 ◽  
Author(s):  
Vanja Zeremski ◽  
Aleksandar Savic ◽  
Vesna Cemerikic-Martinovic ◽  
Ivana Milosevic ◽  
Marina Dragicevic ◽  
...  

Case report. A 41-year-old man presented with anemia, lymphocytosis and splenomegaly. T-cell large granular lymphocyte leukemia was diagnosed based on lymphocytosis of T-cell large granular lymphocytes, characteristic immunophenotype (CD3+, CD8+, CD16+, CD57+) of the lymphocytes and clonally rearranged T-cell receptor genes. Therapy indication was transfusion-dependent anemia. Initial cyclosporine therapy and low-dose oral methotrexate failed to control anemia and lymphocytosis. Yet, a complete clinical and hematological response (without molecular remission) was achieved and sustained when cyclosporine was reintroduced into the therapy. Conclusion. Our case confirms that cyclosporine therapy is effective in treating T-cell large granular lymphocyte leukemia and suggests that indefinite treatment may not be needed to maintain the response.


2019 ◽  
Author(s):  
SANDRA HELENA MACHADO ◽  
YASMINNE ROCHA ◽  
FERNANDA BECKER TABAJARA ◽  
JOÃO VICTOR DE ANDRADE AGUAS ◽  
LETICIA ROSSETTO DAUDT ◽  
...  

2019 ◽  
Author(s):  
PRISCILA GARCIA CÂMARA CABRAL TAVARES ◽  
ANA PAULA DE MENEZES CUNHA ◽  
RUY SAMPAIO SIQUEIRA NETO ◽  
ANDRÉ DE GOIS ROCHA ◽  
LEILA PATRÍCIA FONSECA OLIVEIRA ◽  
...  

2021 ◽  
Vol 82 ◽  
pp. 105858
Author(s):  
K. Chaker ◽  
M. Beghdad ◽  
M.A. Mennouni ◽  
A. Mkhatri ◽  
Y. Oukessou ◽  
...  

2019 ◽  
Vol 64 (2) ◽  
pp. 225-232 ◽  
Author(s):  
Shuang Gao ◽  
Yingming Zhou ◽  
Xiaolong Jin ◽  
Zhongjing Lin ◽  
Yisheng Zhong ◽  
...  

Haematologica ◽  
2018 ◽  
Vol 104 (3) ◽  
pp. e117-e120
Author(s):  
Maya Belhadj ◽  
Dalila Mansour ◽  
Sophie Kaltenbach ◽  
Benedicte Deau-Fischer ◽  
Patricia Franchi ◽  
...  

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