Dynamic expression patterns of tenascin, proteoglycans, and cell adhesion molecules during human hair follicle morphogenesis

1994 ◽  
Vol 199 (2) ◽  
pp. 141-155 ◽  
Author(s):  
Elizabeth D. Kaplan ◽  
Karen A. Holbrook
Keyword(s):  
Cell Adhesion ◽  
Hair Follicle ◽  
Adhesion Molecules ◽  
Human Hair ◽  
Cell Adhesion Molecules ◽  
Expression Patterns ◽  
Human Hair Follicle ◽  
Dynamic Expression

Proteoglycan expression patterns in human hair follicle

2007 ◽  
Vol 158 (2) ◽  
pp. 234-342 ◽  
Author(s):  
S. Malgouries ◽  
S. Thibaut ◽  
B.A. Bernard
Keyword(s):  
Hair Follicle ◽  
Human Hair ◽  
Expression Patterns ◽  
Human Hair Follicle

scholarly journals Alternative Promoter use Governs the Expression of IgLON Cell Adhesion Molecules in Histogenetic Fields of the Embryonic Mouse Brain

2021 ◽  
Author(s):  
Toomas Jagomäe ◽  
Katyayani Singh ◽  
Mari-Anne Philips ◽  
Mohan Jayaram ◽  
Kadri Seppa ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecules ◽  
Cell Adhesion Molecules ◽  
Expression Patterns ◽  
Neuropsychiatric Disorders ◽  
Developing Brain ◽  
Alternative Promoter ◽  
Mrna Isoforms ◽  
Specific Expression ◽  
Embryonic Mouse

The members of the IgLON superfamily of cell adhesion molecules facilitate fundamental cellular communication during brain development, maintain functional brain circuitry, and are associated with several neuropsychiatric disorders. Usage of alternative promoter-specific 1a and 1b mRNA isoforms in Lsamp, Opcml, Ntm and the single promoter of Negr1 in the mouse and human brain has been previously described. To determine the precise spatiotemporal expression dynamics of Lsamp, Opcml, Ntm isoforms and Negr1, in the developing brain, we generated isoform-specific RNA probes and carried out in situ hybridization in the developing (embryonic, E10.5, 13.5, 17; post natal, P0) and adult mouse brains. We show that promoter-specific expression of IgLONs is established early during pallial development (at E10.5), where it remains throughout its differentiation through adulthood. In the diencephalon, midbrain and hindbrain, strong expression patterns are initiated a few days later and begin fading after birth, being only faintly expressed during adulthood. Thus, the expression of specific IgLONs in the developing brain may provide the means for regionally specific functionality as well as for specific regional vulnerabilities. The current study will therefore improve the understanding of how IgLON genes are implicated in the development of neuropsychiatric disorders.

scholarly journals MCAM: A Database to Accelerate the Identification of Functional Cell Adhesion Molecules

2008 ◽  
Vol 6 ◽  
pp. CIN.S341 ◽  
Author(s):  
Anguraj Sadanandam ◽  
Sudipendra Nath Pal ◽  
Joe Ziskovsky ◽  
Prathibha Hegde ◽  
Rakesh K. Singh
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecules ◽  
Cell Adhesion Molecules ◽  
Expression Patterns ◽  
Sequence Information ◽  
Web Based ◽  
Hematopoietic Stem ◽  
Tumor Tissues ◽  
Using Data ◽  
High Throughput Experiments

In the post-genomic era, computational identification of cell adhesion molecules (CAMs) becomes important in defining new targets for diagnosis and treatment of various diseases including cancer. Lack of a comprehensive CAM-specific database restricts our ability to identify and characterize novel CAMs. Therefore, we developed a comprehensive mammalian cell adhesion molecule (MCAM) database. The current version is an interactive Web-based database, which provides the resources needed to search mouse, human and rat-specific CAMs and their sequence information and characteristics such as gene functions and virtual gene expression patterns in normal and tumor tissues as well as cell lines. Moreover, the MCAM database can be used for various bioinformatics and biological analyses including identifying CAMs involved in cell-cell interactions and homing of lymphocytes, hematopoietic stem cells and malignant cells to specific organs using data from high-throughput experiments. Furthermore, the database can also be used for training and testing existing transmembrane (TM) topology prediction methods specifically for CAM sequences. The database is freely available online at http://www.app1.unmc.edu/mcam .

Cell Adhesion Molecules: Selectins and Integrins

1999 ◽  
Vol 19 (5-6) ◽  
pp. 41 ◽  
Author(s):  
Francisco Sanchez-Madrid ◽  
Roberto González-Amaro
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecules ◽  
Cell Adhesion Molecules

A method for culturing human hair follicle cells. (II). Plucked human hair follicles.

1988 ◽  
Vol 50 (2) ◽  
pp. 271-276 ◽  
Author(s):  
Ryuichiro KUWANA ◽  
Seiji ARASE ◽  
Yasushi SADAMOTO ◽  
Hideki NAKANISHI ◽  
Katsuyuki TAKEDA
Keyword(s):  
Hair Follicle ◽  
Human Hair ◽  
Hair Follicles ◽  
Follicle Cells ◽  
Human Hair Follicle
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