Structure and function of the hamster corpus luteum during the estrous cycle

1973 ◽  
Vol 136 (2) ◽  
pp. 235-249 ◽  
Author(s):  
W. W. Leavitt ◽  
C. R. Basom ◽  
J. N. Bagwell ◽  
G. C. Blaha
Keyword(s):  
Corpus Luteum ◽  
Estrous Cycle ◽  
Structure And Function ◽  
And Function

Does prostacyclin (PGI2) support porcine corpus luteum function? – data from in vitro study

2016 ◽  
Vol 62 (5) ◽  
pp. 49
Author(s):  
Magdalena Julia Szymańska ◽  
Agnieszka Blitek
Keyword(s):  
Endothelial Cells ◽  
Mrna Expression ◽  
Corpus Luteum ◽  
Estrous Cycle ◽  
In Vitro Study ◽  
Luteal Cells ◽  
Enzymatic Isolation ◽  
Effective Doses ◽  
And Function

Background. Prostacyclin (PGI2) of luteal origin is involved in the control of corpus luteum (CL) development and function in cattle. PGI2 may regulate the process of angiogenesis and may stimulate progesterone (P4) secretion by luteal cells via its specific receptors, PTGIR. In contrast to cattle, the role of PGI2 in the pig CL has not yet been described.Aim. The present study aimed to investigate the effect of PGI2 on 1) P4 secretion by luteal cells, and 2) the expression of angiogenesis-related genes in endothelial cells of the porcine CL.Methods. CL collected from gilts on day 5-7 of the estrous cycle were used for enzymatic isolation of luteal (Experiment 1) and endothelial (Experiment 2) cells. In Exp. 1, cultured luteal cells were incubated with increasing (0, 0.01, 0.1, 1, 5 µM) doses of PGI2 analogues: iloprost (ILO) and carbaprostacyclin (cPGI2) for 8 h. To determine the effective doses of PGI2 analogues, P4 concentration in culture medium was examined by RIA. Thereafter, luteal cells were treated with ILO and cPGI2 at the concentration of 1 and 5 µM in the presence or absence of PTGIR antagonist (CAY10441). After 8 h of incubation the medium was collected for P4 determination. In Exp. 2, isolated endothelial cells were treated for 24 h with ILO and cPGI2 at doses of 1 and 5 µM. Then, cells were collected for analysis of Ang-1 and -2 mRNA expression using qPCR.Results. Both, ILO and cPGI2 affected P4 secretion by luteal cells. Elevated levels of P4 were observed in medium after treatment of luteal cells with 1 µM of ILO and 0.1, 1 and 5 µM of cPGI2 compared with control values (p<0.05). The addition of CAY10441 inhibited the stimulatory effect of ILO on P4 secretion, while did not change P4 production by luteal cells incubated with cPGI2. Moreover, PGI2 analogues differentially affected (p<0.05) the expression of proangiogenic factors. ILO stimulated Ang-2, whereas cPGI2 positively affected Ang-1 mRNA expression in endothelial cells at concentrations of 1 µM and 5 µM, respectively.Conclusion. PGI2 affects P4 secretion during luteal phase of the estrous cycle and may regulate the process of angiogenesis in the porcine CL.

The structure and function of the corpus luteum

2021 ◽  
Vol 20 (7) ◽  
pp. 775-775
Author(s):  
A. Timofeev
Keyword(s):  
Corpus Luteum ◽  
Structure And Function ◽  
And Function

Jaff (Zentr. F. G., 1924,. No. 21) indicates that the division of the development of the corpus luteum into stages according to Rge does not correspond to reality.

The fine structure of the camel corpus luteum of early pregnancy and after parturition

1978 ◽  
Vol 36 (2) ◽  
pp. 558-559
Author(s):  
R. K. Nayak
Keyword(s):  
Fine Structure ◽  
Corpus Luteum ◽  
Early Pregnancy ◽  
Smooth Endoplasmic Reticulum ◽  
Structure And Function ◽  
Critical Study ◽  
Endocrine Gland ◽  
The One ◽  
And Function

The structure and function of the corpus luteum has been studied intensively, yet many of the factors and events in formation, maintenance, function and regression of this endocrine gland remain unclear. Christensen and Gillim reviewed the literature dealing with steroid-secreting cells including lutein cells. They clearly documented the role of smooth endoplasmic reticulum in steroid biosynthesis. The fine structure of the corpus luteum has been described in a variety of animals including rat, mouse, hamster, guinea pig, rabbit, pig, cow, sheep, deer, dog, racoon, mink, badger, lemur, armadillo and man. Recently, Enders reviewed in detail the results obtained on the cytology of corpus luteum granulosa lutein cells of early pregnancy.Novoa has recently attempted to correlate some reproductive phenomena in Camelidae with those of other domestic animals. Since the literature is essentially devoid of information on electron microscopy of the camel corpus luteum and since fresh camel corpus luteum specimens were obtained in excellent condition, a critical study was undertaken to provide definitive information on the structure and function of the corpus luteum during early stages of pregnancy and after parturition in the one-humped camel, Camelus dromedarius.

A Model for the Control of the Rat Estrous Cycle

1969 ◽  
Vol 91 (2) ◽  
pp. 321-324 ◽  
Author(s):  
Neena B. Schwartz
Keyword(s):  
Computer Simulation ◽  
Theoretical Model ◽  
Estrous Cycle ◽  
Reproductive Cycle ◽  
Adaptive Significance ◽  
Structure And Function ◽  
Reproduction System ◽  
System A ◽  
Cyclic Function ◽  
And Function

This paper first reviews the basic elements of the reproduction system in female mammals and indicates the adaptive significance of the cyclicity of structure and function always observed in this system. A detailed description of the reproductive cycle in the laboratory rat is then presented, and a theoretical model of the control of the rat estrous cycle is described. The purpose of the model is to “explain” the mechanism of cyclic function of reproduction in the rat. Some examples of the heuristic value of the model are then outlined, including the beginning of computer simulation.

scholarly journals Escherichia coli lipopolysaccharide administration transiently suppresses luteal structure and function in diestrous cows

Reproduction ◽  
2012 ◽  
Vol 144 (4) ◽  
pp. 467-476 ◽  
Author(s):  
K Herzog ◽  
K Strüve ◽  
J P Kastelic ◽  
M Piechotta ◽  
S E Ulbrich ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Estrous Cycle ◽  
Structure And Function ◽  
Plasma Progesterone ◽  
Luteal Cells ◽  
Subsequent Cycle ◽  
Or Gene ◽  
And Function ◽  
Escherichia Coli Lipopolysaccharide ◽  
Lps Treatment

The objective was to characterize the effects of Escherichia coli lipopolysaccharide (LPS) endotoxin (given i.v.) on luteal structure and function. Seven nonlactating German Holstein cows, 5.1±0.8 years old (mean±s.e.m.), were given 10 ml saline on day 10 (ovulation=day 1) of a control estrous cycle. On day 10 of a subsequent cycle, they were given 0.5 μg/kg LPS. Luteal size decreased (from 5.2 to 3.8 cm2, P≤0.05) within 24 h after LPS treatment and remained smaller throughout the remainder of the cycle. Luteal blood flow decreased by 34% (P≤0.05) within 3 h after LPS and remained lower for 72 h. Plasma progesterone (P4) concentrations increased (P≤0.05) within the first 3 h after LPS but subsequently declined. Following LPS treatment, plasma prostaglandin (PG) F metabolites concentrations were approximately tenfold higher in LPS-treated compared with control cows (9.2 vs 0.8 ng/ml, P≤0.05) within 30 min, whereas plasma PGE concentrations were nearly double (P≤0.05) at 1 h after LPS. At 12 h after treatment, levels of mRNA encoding Caspase-3 in biopsies of the corpus luteum (CL) were increased (P≤0.05), whereas those encoding StAR were decreased (P≤0.05) in cattle given LPS vs saline. The CASP3 protein was localized in the cytoplasm and/or nuclei of luteal cells, whereas StAR was detected in the cytosol of luteal cells. In the estrous cycle following treatment with either saline or LPS, there were no significant differences between groups on luteal size, plasma P4 concentrations, or gene expression. In conclusion, LPS treatment of diestrus cows transiently suppressed both the structure and function of the CL.

Interrelationships among morphology, echotexture, and function of the bovine corpus luteum during the estrous cycle

2009 ◽  
Vol 115 (1-4) ◽  
pp. 18-28 ◽  
Author(s):  
Luiz Gustavo B. Siqueira ◽  
Ciro A.A. Torres ◽  
Lincoln S. Amorim ◽  
Eliza D. Souza ◽  
Luiz Sérgio A. Camargo ◽  
...  
Keyword(s):  
Corpus Luteum ◽  
Estrous Cycle ◽  
Bovine Corpus Luteum ◽  
And Function

The structure and function of the corpus luteum

1976 ◽  
Vol 3 (1) ◽  
pp. 43-61
Author(s):  
GEORGEANNA SEEGAR JONES ◽  
ANNE COLSTON WENTZ
Keyword(s):  
Corpus Luteum ◽  
Structure And Function ◽  
And Function
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