scholarly journals Postnatal growth and variability of the body and of the various organs in the albino rat

1913 ◽  
Vol 15 (1) ◽  
pp. 1-68 ◽  
Author(s):  
C. M. Jackson
Keyword(s):  
The Body ◽  
2021 ◽  
Vol 15 (11) ◽  
pp. 2938-2941
Author(s):  
Fauzia Qureshi ◽  
Syeda Rizwana Jafri ◽  
Hafiza Sadia Ahmad ◽  
Uzma Waseem ◽  
Ursula Akif ◽  
...  

Background: Ovulation induction with clomiphene citrate in women with infertility has been practiced more than 40% years but in infertile patients this treatment plan proved to be ineffective with multiple complication. Body weight plays an important role modulating reproductive development and functioning. Aim: To observe the effects on body weight of female albino rat after use of clomiphene citrate and letrozole for consecutive 1-4 estrous cycles Method: Eighty four adult female Albino rats were equally divided into three groups for this research. Body weight of each rat was measured before and after the experiment. Vaginal smear cytology of each rat was performed to study different phases of estrous cycle. Control group A was given normal saline orally , In Experimental group B rats were given letrozole (Femara) at dose 5mg/kg orally and in Experimental group C rats were given clomiphene citrate at dose 100ug/kg orally. Results: Significant weight gain is observed in rats taking clomiphene citrate as compared to letrozole Conclusion : Comiphene citrate directly affects the body weight which indirectly reduces the ovulation induction and pregnancy rate. Letrozole is good alternate for ovulation induction and for CC resistant patients. Keywords: Estrous cycle, body weight, citrate and letrozole


2007 ◽  
Vol 23 (7) ◽  
pp. 439-444 ◽  
Author(s):  
Suresh C Joshi ◽  
R. Mathur ◽  
N. Gulati

Organophosphates are among the most widely used synthetic insect pesticides. The widespread use of organophosphates has stimulated research into the possible existence of effects related with their reproductive toxic activity. Present study was therefore, undertaken to assess the effects of chlorpyrifos on testes, the main organ of male reproduction. Chlorpyrifos at the dose levels of 7.5, 12.5 and 17.5 mg/kg b. wt./day was administered orally to male rats of Wistar strain for 30 days to evaluate the toxic alterations in testicular histology, biochemistry, sperm dynamics and testosterone levels. The body weight of animals did not show any significant change, however, a significant reduction was observed in testes. Chlorpyrifos also brought about marked reduction in epididymal and testicular sperm counts in exposed males and a decrease in serum testosterone concentration. Histopathological examination of testes showed mild to severe degenerative changes in seminiferous tubules at various dose levels. Fertility test showed 85% negative results. A significant reduction in the sialic acid content of testes and testicular glycogen was noticed, whereas the protein and cholesterol content was raised at significant levels. All these toxic effects are moderate at low doses and become severe at higher dose levels. From the results of the present study it is concluded that chlorpyrifos induces severe testicular damage and results in reduction in sperm count and thus affect fertility. Small changes in sperm counts are known to have adverse affects on human fertility. Therefore, application of such insecticide should be limited to a designed programme. Toxicology and Industrial Health 2007; 23: 439—444.


1915 ◽  
Vol 9 (10) ◽  
pp. 751-776 ◽  
Author(s):  
Helen Dean King
Keyword(s):  
The Body ◽  

1983 ◽  
Vol 98 (3) ◽  
pp. 351-356 ◽  
Author(s):  
G. J. Boer ◽  
M. Rieutort

Levels of GH in serum were assayed during the development of heterozygous (HET) control and vasopressin-deficient homozygous (HOM) Brattleboro rats. In early postnatal growth no differences in GH concentrations were present between HET and HOM rats for the rapid decline in serum levels of GH in the first week and the constant period up to day 24 of age thereafter. However, higher values were found in 55-day-old HOM rats and lower values at the age of 9 months. It is concluded that the stunted development of the body and brain of HOM rats is not GH-related, and that changes or anomalies in GH secretion appear only after neurogenesis has been completed.


2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Mohsen Javadzadeh ◽  
Hedieh Saneifard ◽  
Amir Hossein Hosseini

Russell-Silver syndrome is a genetic disorder the inheritance pattern of which is mostly sporadic. Some of the features of the syndrome are present at birth, and others appear in later years. The main clinical features include low birth weight, poor growth postnatally, short height, and discrepancies in size between the two sides of the body Abu-Amera et al. (2008), Binder et al. (2011). There is no statistical significant difference in prevalence between males and females. We report a case of Russell-Silver syndrome with intrauterine and postnatal growth retardation, triangular face, and body asymmetry, in addition to torticollis as a novel manifestation. In neck sonography, we found asymmetry of sternocleidomastoid muscles. In conclusion, we describe torticollis as a presentation of Russell-Silver syndrome.


Author(s):  
Robin M. Bernstein ◽  
Barry Bogin

An evolutionary and biocultural approach is taken to the study of human growth and development. The evolutionary perspective focuses on the unusual process of human postnatal growth and development, a process that takes two decades to complete and traverses the stages of infancy, childhood, juvenility, and adolescence. Human childhood and adolescence are highly unusual even compared to our closest living relatives, perhaps unique. The biocultural perspective of human development focuses on the constant interaction taking place during all phases of human development between genes and hormones within the body and the sociocultural environment that surrounds the body. While humans are often considered to be cooperative breeders, depending on social group helpers to successfully rear offspring, it may be more accurate to understand humans as practising biocultural reproduction as an adaptation to minimise risks to health.


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