Insights into influence mechanism of polymeric excipients on dissolution of drug formulations: a molecular interaction‐based theoretical model analysis and prediction

AIChE Journal ◽  
2021 ◽  
Author(s):  
Yuanhui Ji ◽  
Dule Hao ◽  
Christian Luebbert ◽  
Gabriele Sadowski
Keyword(s):  
Theoretical Model ◽  
Molecular Interaction ◽  
Model Analysis ◽  
Drug Formulations ◽  
Influence Mechanism

Research on Dynamic Design Method Based on Measuring Information for Printing Press

2010 ◽  
Vol 174 ◽  
pp. 290-294
Author(s):  
Yi Ming Wang ◽  
Bang She Chen ◽  
Yan Li ◽  
Shao Hua Zhang
Keyword(s):  
Theoretical Model ◽  
Dynamic Characteristics ◽  
High Speed ◽  
Design Method ◽  
Model Analysis ◽  
Printing Press ◽  
Vibration Measurement ◽  
Dynamic Design ◽  
Analysis Experiment ◽  
Printing Machine

Printing machinery’s reliability is one of the most important index parameter and good dynamic characteristics are essential for high speed printing press. The dynamic characteristic is predictable for printing machine with dynamic design. With the complexity of printing technique and printing machine, information, such as load on components is lack, leading to the difficulty of dynamic model solving and further more the dynamic parameters needs to be verified. Firstly, according to the dynamic design method, a dynamic design process based on measuring information for printing machine was put forward. Secondly, on the basis of principle and structure analysis to typical printing machine, dynamic characteristics measurement item and method was determined. With a wallboard of a two-color offset press acting as an example, the utilizing method was illustrated through dynamic modeling, theoretical model analysis, experiment model analysis based on vibration measurement and comparing the theoretical and experimental results. Finally, a Dynamic Design Assistant Platform based Vibration Measurement for Printing Machine was developed and had been used in 10 kinds of printing machine measurement and analysis. The conclusion shows that the tolerance of the theoretical model analysis results and experiment results is allowed. A new approach for new printing machine design and optimal design for existed printing machine is given.

Reflected sound field by stage floors in the concert halls: Theoretical model analysis

1998 ◽  
Vol 103 (5) ◽  
pp. 2749-2749 ◽  
Author(s):  
Shinsuke Nakanishi ◽  
Kimihiro Sakagami ◽  
Masayuki Morimoto
Keyword(s):  
Theoretical Model ◽  
Sound Field ◽  
Model Analysis ◽  
Concert Halls

Fatigue investigation of a railway truss bridge

1984 ◽  
Vol 11 (3) ◽  
pp. 625-631 ◽  
Author(s):  
Z. L. Szeliski ◽  
I. A. Elkholy
Keyword(s):  
Theoretical Model ◽  
Sample Size ◽  
Fatigue Damage ◽  
Field Measurement ◽  
High Strength ◽  
Traffic Analysis ◽  
Model Analysis ◽  
Remaining Life ◽  
Repetitive Loading ◽  
Truss Bridge

The advent of unit trains and high gross tonnage has made it necessary to evaluate the effect of repetitive loading on bridges. A description of a fatigue investigation of a 35.7 m (117 ft) railway through truss span is presented. The study consisted of (1) field measurement; (2) theoretical model analysis; (3) traffic analysis; (4) estimate of fatigue damage; (5) evaluation of fatigue detail category; (6) estimate of remaining life; and (7) action required. The effect of car sequence in trains, sample size, flat wheels, and impact on level of stresses is examined. As a result of the study, the trusses were retrofitted by removing rivets, reaming holes, and placing high-strength bolts.

Experimental and Theoretical Validations on Ternary Mixtures-II

2020 ◽  
Vol 12 (7) ◽  
pp. 900-903
Author(s):  
L. Palaniappan ◽  
S. Nithiyanantham
Keyword(s):  
Theoretical Model ◽  
Sound Velocity ◽  
Model Theory ◽  
Molecular Interaction ◽  
Ternary Systems ◽  
Ternary Mixtures ◽  
Relative Merit ◽  
Organic Liquids ◽  
Ultrasonic Sound

The molecular interaction analyses have been carried out in some ternary systems at 303 K with validation of ultrasonic sound velocity. The theory which is suitable for appropriate model/theory. In this present paper the molecular interaction among the organic liquids deals with experimentally measured values and validate with theoretical model. Finally the relative merit and demerit are discussed and interpreted.

scholarly journals A Model Analysis of Tensile Stress in the Toadfish Vestibular Membranes

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Daniel J. Pender
Keyword(s):  
Theoretical Model ◽  
Tensile Stress ◽  
Semicircular Canal ◽  
Hoop Stress ◽  
Peak Stress ◽  
Model Analysis ◽  
Stress Factor ◽  
Vestibular Labyrinth ◽  
The Mean

Background. A theoretical model analysis of stress in the vestibular membranes has identified a geometrical stress factor incorporating shape, size, and thickness that can be used to assess peak stress in the various chambers.Methods. Using published measurements of the toadfish vestibular membranes made during surgery, the geometrical stress factor can be evaluated for each chamber based on the model.Results. The mean geometrical stress factor is calculated to be the lowest in the semicircular canal (4.4), intermediate in the ampulla (6.0), and the highest in the utricle (17.4).Conclusions. The model predicts that substantial hoop stress disparities exist in the toadfish vestibular labyrinth. Stress is least in the semicircular canal, which therefore appears to be the structure with greatest stability. The utricle is found to be the most stress prone structure in the vestibular labyrinth and therefore appears to be the chamber most vulnerable to distention and potential modification.

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