Gravitational discharge of fine dry powders with asperities from a conical hopper

AIChE Journal ◽  
2017 ◽  
Vol 64 (2) ◽  
pp. 427-436 ◽  
Author(s):  
Hui Lu ◽  
Jia Zhong ◽  
Gui-Ping Cao ◽  
Hai-Feng Liu
Keyword(s):  
Dry Powders ◽  
Conical Hopper

scholarly journals Conical Hopper Design Parameters for Selected Food Powders using MS Excel Add-in

2015 ◽  
Vol 113 (11) ◽  
pp. 29-33
Author(s):  
C. O.C.Oko ◽  
E.O. Diemuodeke ◽  
D.Edet D.Edet
Keyword(s):  
Design Parameters ◽  
Food Powders ◽  
Conical Hopper

Dispersibility of lactose fines as compared to API in dry powders for inhalation

2016 ◽  
Vol 504 (1-2) ◽  
pp. 27-38 ◽  
Author(s):  
Kyrre Thalberg ◽  
Simon Åslund ◽  
Marcus Skogevall ◽  
Patrik Andersson
Keyword(s):  
Dry Powders

scholarly journals Challenges Associated with the Pulmonary Delivery of Therapeutic Dry Powders for Preclinical Testing

2019 ◽  
Vol 36 (0) ◽  
pp. 129-144 ◽  
Author(s):  
Dominique N. Price ◽  
Nitesh K. Kunda ◽  
Pavan Muttil
Keyword(s):  
Pulmonary Delivery ◽  
Preclinical Testing ◽  
Dry Powders

Suspension Plasma Spraying (SPS) of Cobalt Spinel

1997 ◽  
Author(s):  
G. Schiller ◽  
M. Müller ◽  
F. Gitzhofer ◽  
M.I. Boulos ◽  
R.B. Heimann
Keyword(s):  
Plasma Spraying ◽  
Inductively Coupled Plasma ◽  
Solid Phase ◽  
Spinel Phase ◽  
Rf Plasma ◽  
Dry Powders ◽  
Inductively Coupled ◽  
Cobalt Spinel ◽  
Chemical Conditions ◽  
Physical And Chemical

Abstract Fine (median size 6 μm and 0.3 μm) cobalt spinel (Co3O4) powders were processed suspended in a suitable liquid phase. Suspensions exceeding 50 wt.% solid phase content were successfully injected into an inductively coupled plasma. Spheroidized powders with large particle size (up to 80 μm) were prepared, and cobalt oxide coatings were produced by this novel RF-SPS method. The microstructural features of the coatings can be controlled by parameter optimization similarly to plasma spraying of dry powders. Numerous variations of the physical and chemical conditions of the process were performed in an attempt to overcome the main disadvantage of the process, i.e. the decomposition of the spinel phase to CoO. So far, the spinel phase could be reestablished only by a post-treatment of the deposited coatings with atomic oxygen in the RF plasma.

Engineering Advances in Spray Drying for Pharmaceuticals

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
John M. Baumann ◽  
Molly S. Adam ◽  
Joel D. Wood
Keyword(s):  
Spray Drying ◽  
Oral Delivery ◽  
Process Development ◽  
Solid Dispersions ◽  
Amorphous Solid ◽  
Annual Review ◽  
Publication Date ◽  
Dry Powders ◽  
Wide Range ◽  
Pharmaceutical Industries

Spray drying is a versatile technology that has been applied widely in the chemical, food, and, most recently, pharmaceutical industries. This review focuses on engineering advances and the most significant applications of spray drying for pharmaceuticals. An in-depth view of the process and its use is provided for amorphous solid dispersions, a major, growing drug-delivery approach. Enhanced understanding of the relationship of spray-drying process parameters to final product quality attributes has made robust product development possible to address a wide range of pharmaceutical problem statements. Formulation and process optimization have leveraged the knowledge gained as the technology has matured, enabling improved process development from early feasibility screening through commercial applications. Spray drying's use for approved small-molecule oral products is highlighted, as are emerging applications specific to delivery of biologics and non-oral delivery of dry powders. Based on the changing landscape of the industry, significant future opportunities exist for pharmaceutical spray drying. Expected final online publication date for the Annual Review of Chemical and Biomolecular Engineering, Volume 12 is June 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Explosion mitigation of methane‐air mixture in combined application of inert gas and ABC dry powders in a closed compartment

2019 ◽  
Vol 39 (2) ◽  
Author(s):  
Manhou Li ◽  
Jingchao Xu ◽  
Quan Li ◽  
Changjian Wang ◽  
Baozhen Wang ◽  
...  
Keyword(s):  
Inert Gas ◽  
Dry Powders ◽  
Combined Application ◽  
Explosion Mitigation
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