scholarly journals Treatment of intrahepatic recurrence after hepatectomy for hepatocellular carcinoma

2021 ◽  
Author(s):  
Michinori Matsumoto ◽  
Katsuhiko Yanaga ◽  
Hiroaki Shiba ◽  
Shigeki Wakiyama ◽  
Taro Sakamoto ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Intrahepatic Recurrence

Patterns of intrahepatic recurrence after curative resection of hepatocellular carcinoma

Hepatology ◽  
1989 ◽  
Vol 9 (3) ◽  
pp. 457-460 ◽  
Author(s):  
Takashi Matsumata ◽  
Takashi Kanematsu ◽  
Kenji Takenaka ◽  
Yasuhiro Yoshida ◽  
Takashi Nishizaki ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Curative Resection ◽  
Intrahepatic Recurrence

scholarly journals Contrast-Enhanced Ultrasound to Monitor Early Recurrence of Primary Hepatocellular Carcinoma after Curative Treatment

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Lian-Feng Liu ◽  
Zhan-Ling Ding ◽  
Jian-Hong Zhong ◽  
Hong-Xue Li ◽  
Jun-Jie Liu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Recurrent Disease ◽  
Intrahepatic Recurrence ◽  
Primary Hepatocellular Carcinoma ◽  
Curative Treatment ◽  
Arterial Phase ◽  
Contrast Enhanced Ultrasound ◽  
Enhancement Pattern ◽  
Recurrent Hepatocellular Carcinoma ◽  
Contrast Enhanced

Objective. To evaluate contrast-enhanced ultrasound (CEUS) for monitoring early intrahepatic recurrence of primary hepatocellular carcinoma (HCC) after curative treatment. Methods. We prospectively analyzed 97 patients (124 nodules) with primary HCC who underwent hepatic resection or radiofrequency ablation and subsequently experienced intrahepatic recurrence. Patients were assessed with conventional ultrasound and CEUS. They were also assessed with contrast-enhanced computed tomography (CECT) and/or magnetic resonance imaging (MRI). The image characteristics of CEUS of recurrent hepatocellular carcinoma and high-grade dysplastic nodules (HGDNs) were analyzed. In addition, the ability of CEUS and CECT/MRI to assess internal artery vascularization in recurrent disease was compared. Results. CEUS of recurrent hepatocellular carcinoma showed hyperenhancement in the arterial phase in 96 of 99 nodules, and it showed hypo- or isoenhancement for portal venous and delayed phases. The most common enhancement patterns were “fast-in and slow-out” and “fast-in and fast-out”. Based on the arterial hyperenhancement of lesions and with clinical data such as patient history of HCC and increased level of serum alpha-fetoprotein, the diagnostic accuracy of CEUS for recurrent HCC was significantly higher than that based on the enhancement pattern of “fast-in and fast-out”. CEUS of HGDNs showed local or global hyperenhancement during the arterial phase, isoenhancement during the portal venous phase, and isoenhancement or slight hypoenhancement during the delayed phase. The enhancement pattern was “fast-in and slow-out”. In some cases, it was difficult to differentiate HGDNs from recurrent disease using CEUS. Vascularization in recurrent disease was significantly higher when assessed by CEUS than when assessed with CECT/MRI (P < 0.05). For detecting recurrent disease, CEUS showed sensitivity of 97.0%, specificity of 68.0%, positive predictive value of 92.3%, and negative predictive value of 85.0%. The corresponding parameters for CECT/MRI were 71.7%, 72.0%, 88.8%, and 39.1%. Conclusion. Intrahepatic recurrent HCC and HGDNs with diameter ≤ 3.0 cm have a characteristic appearance on CEUS. This imaging modality may be effective for monitoring early intrahepatic recurrence after curative treatment of primary HCC.

scholarly journals Intrahepatic recurrence of single nodular hepatocellular carcinoma after surgical resection: an analysis by segmental distribution

2018 ◽  
Vol 88 (12) ◽  
pp. E840-E844
Author(s):  
Jin-Min Kim ◽  
Seung-Hyun Lee ◽  
Woo Young Shin ◽  
Keon-Young Lee ◽  
Jun Mee Kim ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Surgical Resection ◽  
Intrahepatic Recurrence

Protein expression associated with early intrahepatic recurrence of hepatocellular carcinoma after curative surgery

2007 ◽  
Vol 98 (5) ◽  
pp. 665-673 ◽  
Author(s):  
Hideki Yokoo ◽  
Tadashi Kondo ◽  
Tetsuya Okano ◽  
Kazuaki Nakanishi ◽  
Michiie Sakamoto ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Protein Expression ◽  
Intrahepatic Recurrence ◽  
Curative Surgery

Incidence and factors associated with intrahepatic recurrence following resection of hepatocellular carcinoma

1993 ◽  
Vol 105 (2) ◽  
pp. 488-494 ◽  
Author(s):  
Naofumi Nagasue ◽  
Masaaki Uchida ◽  
Yoshinari Makino ◽  
Yoshinari Takemoto ◽  
Akira Yamanoi ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Intrahepatic Recurrence ◽  
Factors Associated
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