A Single‐Molecule and Logic Gate via Optical and Acid–Base Control

2020 ◽  
Vol 3 (10) ◽  
pp. 2000163
Author(s):  
Wenkai Zhao ◽  
Dongqing Zou ◽  
Zhaopeng Sun ◽  
Yuqing Xu ◽  
Guomin Ji ◽  
...  
Keyword(s):  
Single Molecule ◽  
Logic Gate ◽  
Acid Base

A Molecular Logic Gate Enables Super-Resolved Imaging of Intracellular Lipid Droplets

2019 ◽  
Author(s):  
Adam Eördögh ◽  
Carolina Paganini ◽  
Dorothea Pinotsi ◽  
Paolo Arosio ◽  
Pablo Rivera-Fuentes
Keyword(s):  
Single Molecule ◽  
Lipid Droplets ◽  
Neutral Lipids ◽  
Logic Gate ◽  
Living Cells ◽  
Three Dimensions ◽  
Single Molecule Imaging ◽  
Molecular Logic Gate ◽  
Molecular Logic ◽  
Cellular Compartments

<div>Photoactivatable dyes enable single-molecule imaging in biology. Despite progress in the development of new fluorophores and labeling strategies, many cellular compartments remain difficult to image beyond the limit of diffraction in living cells. For example, lipid droplets, which are organelles that contain mostly neutral lipids, have eluded single-molecule imaging. To visualize these challenging subcellular targets, it is necessary to develop new fluorescent molecular devices beyond simple on/off switches. Here, we report a fluorogenic molecular logic gate that can be used to image single molecules associated with lipid droplets with excellent specificity. This probe requires the subsequent action of light, a lipophilic environment and a competent nucleophile to produce a fluorescent product. The combination of these requirements results in a probe that can be used to image the boundary of lipid droplets in three dimensions with resolutions beyond the limit of diffraction. Moreover, this probe enables single-molecule tracking of lipids within and between droplets in living cells.</div>

Investigation of an Acid–Base and Redox Molecular Switch: From Bulk to the Single-Molecule Level

2007 ◽  
Vol 13 (25) ◽  
pp. 7066-7074 ◽  
Author(s):  
Rabih O. Al-Kaysi ◽  
José Luis Bourdelande ◽  
Iluminada Gallardo ◽  
Gonzalo Guirado ◽  
Jordi Hernando
Keyword(s):  
Single Molecule ◽  
Molecular Switch ◽  
Acid Base ◽  
Single Molecule Level

scholarly journals Long starphene single molecule NOR Boolean logic gate

2018 ◽  
Vol 678 ◽  
pp. 163-168 ◽  
Author(s):  
W.H. Soe ◽  
C. Manzano ◽  
P. de Mendoza ◽  
P.R. McGonigal ◽  
A.M. Echavarren ◽  
...  
Keyword(s):  
Single Molecule ◽  
Logic Gate ◽  
Boolean Logic

Single-Molecule Sensing of Interfacial Acid–Base Chemistry

2020 ◽  
Vol 11 (23) ◽  
pp. 10023-10028 ◽  
Author(s):  
Cai-Ping Tao ◽  
Chen-Chen Jiang ◽  
Ya-Hao Wang ◽  
Ju-Fang Zheng ◽  
Yong Shao ◽  
...  
Keyword(s):  
Single Molecule ◽  
Acid Base

scholarly journals A Molecular Logic Gate Enables Single-Molecule Imaging and Tracking of Lipids in Intracellular Domains

2020 ◽  
Vol 15 (9) ◽  
pp. 2597-2604
Author(s):  
Ádám Eördögh ◽  
Carolina Paganini ◽  
Dorothea Pinotsi ◽  
Paolo Arosio ◽  
Pablo Rivera-Fuentes
Keyword(s):  
Single Molecule ◽  
Logic Gate ◽  
Single Molecule Imaging ◽  
Molecular Logic Gate ◽  
Molecular Logic ◽  
Intracellular Domains

Demonstration of a NOR logic gate using a single molecule and two surface gold atoms to encode the logical input

2011 ◽  
Vol 83 (15) ◽  
Author(s):  
W.-H. Soe ◽  
C. Manzano ◽  
A. De Sarkar ◽  
F. Ample ◽  
N. Chandrasekhar ◽  
...  
Keyword(s):  
Single Molecule ◽  
Logic Gate ◽  
Nor Logic Gate

Manipulating Molecular Quantum States with Classical Metal Atom Inputs: Demonstration of a Single Molecule NOR Logic Gate

ACS Nano ◽  
2011 ◽  
Vol 5 (2) ◽  
pp. 1436-1440 ◽  
Author(s):  
We-Hyo Soe ◽  
Carlos Manzano ◽  
Nicolas Renaud ◽  
Paula de Mendoza ◽  
Abir De Sarkar ◽  
...  
Keyword(s):  
Metal Atom ◽  
Single Molecule ◽  
Logic Gate ◽  
Quantum States ◽  
Nor Logic Gate
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