Dimethyl Sulfoxide Oxygen Donor‐Based Annulation of Ketones and Ammonium Persulfate: Regioselective Synthesis of 2,4‐disubstituted Oxazoles

2019 ◽  
Vol 361 (7) ◽  
pp. 1632-1640 ◽  
Author(s):  
Zhongzhong Cao ◽  
Huifang Lv ◽  
Yufeng Liu ◽  
Zhiwen Nie ◽  
Haiping Liu ◽  
...  
Keyword(s):  
Dimethyl Sulfoxide ◽  
Ammonium Persulfate ◽  
Regioselective Synthesis ◽  
Oxygen Donor

Structure and Stereochemistry of Adducts of Tris(dipivaloylmethanato)europium(III), Eu(dpm)3, with Some Dipolar Aprotic Unidentate O-Donors

2020 ◽  
Vol 73 (6) ◽  
pp. 455
Author(s):  
Eric J. Chan ◽  
Jack M. Harrowfield ◽  
Brian W. Skelton ◽  
Alexandre N. Sobolev ◽  
Allan H. White
Keyword(s):  
Single Crystal ◽  
Dimethyl Sulfoxide ◽  
The Other ◽  
Asymmetric Unit ◽  
X Ray ◽  
Metal Atoms ◽  
Oxygen Donor ◽  
Trigonal Prismatic

Single crystal X-ray structural characterisations are reported for adducts of the form [(L-O)Eu(O,O′-dpm)3] obtained by the crystallisation of tris(dipivaloylmethanato)europium(iii) (dpm=[HC(C(tBu).CO)2]−) from an array of dipolar aprotic oxygen-donor solvents L (L=N-methylpyrrolidinone (nmp), trimethylphosphate, (MeO)3PO, (tmp), hexamethylphosphoramide (hmpa), dimethylacetamide (dma), dimethyl sulfoxide (dmso), and the bidentate octamethylpyrophosphoramide (ompa). In all adducts, the resulting arrays contain seven-coordinate metal atoms, which adopt two different isomeric forms of the mono-capped trigonal prismatic stereochemistry, the L=dma and dmso adducts corresponding to one type, nmp and tmp the other. The adduct formed with ompa behaves as a pair of discrete metal environments bridged by the O-ompa-O′ ligand, thus; [(dpm-O,O′)3Eu(O-ompa-O′)Eu(O,O′-dpm)3], and is found in two forms, one in which both Eu environments is of the tmp type, the other of the dmso/dma type. In the hmpa adduct, the asymmetric unit of the structure is a disordered composite of both types. In none of the adducts is there any further solvation beyond coordination of a single L.

Synthesis and Gas Sensing Property of Poly(m-aminophenol)

2013 ◽  
Vol 710 ◽  
pp. 89-92
Author(s):  
Wei Ping Tang
Keyword(s):  
Fourier Transform ◽  
Aqueous Solutions ◽  
Dimethyl Sulfoxide ◽  
Laser Scanning ◽  
Gas Sensing ◽  
Ammonium Persulfate ◽  
Confocal Microscope ◽  
Basic Medium ◽  
Laser Scanning Confocal Microscope ◽  
Ethanol Sensing

Poly (m-aminophenol) (PmAP) was synthesized chemically from aqueous solutions of the monomer meta-aminophenol in the initially basic medium by using ammonium persulfate as an oxidant. The synthesized PmAP was characterized by Fourier transform infrared spectroscopic. The film of PmAP was formed by dissolving PmAP in the dimethyl sulfoxide followed by solvent removel. The morphology of the film was obeserved by laser scanning confocal microscope (LSCM) and the ethanol sensing property was studied by testing the resistance of the PmAP film when purged air and ethanol alternately.

scholarly journals Radical-mediated dehydrative preparation of cyclic imides using (NH4)2S2O8–DMSO: application to the synthesis of vernakalant

2015 ◽  
Vol 11 ◽  
pp. 1008-1016 ◽  
Author(s):  
Dnyaneshwar N Garad ◽  
Subhash D Tanpure ◽  
Santosh B Mhaske
Keyword(s):  
Dimethyl Sulfoxide ◽  
Ammonium Persulfate ◽  
Primary Amines ◽  
Radical Mechanism ◽  
Forming Process ◽  
One Pot ◽  
Practical Synthesis ◽  
Cyclic Imides ◽  
Cyclic Anhydrides ◽  
High Yields

Ammonium persulfate–dimethyl sulfoxide (APS–DMSO) has been developed as an efficient and new dehydrating reagent for a convenient one-pot process for the synthesis of miscellaneous cyclic imides in high yields starting from readily available primary amines and cyclic anhydrides. A plausible radical mechanism involving DMSO has been proposed. The application of this facile one-pot imide forming process has been demonstrated for a practical synthesis of vernakalant.

A Unique Rare-Earth Cluster within a Calixarene Sandwich: Parallels in the Chemistry of Cyclosiloxanes and Calixarenes

2000 ◽  
Vol 53 (12) ◽  
pp. 895 ◽  
Author(s):  
Alexander Bilyk ◽  
Annegret K. Hall ◽  
Jack M. Harrowfield ◽  
Mir Wais Hosseini ◽  
Brian W. Skelton ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Rare Earth ◽  
Dimethyl Sulfoxide ◽  
Hydroxyl Group ◽  
Oxygen Donor ◽  
The Rare Earth

Determination of the crystal structure of a complex obtained by the reaction of the dimethyl sulfoxide (dmso) solvate of neodymium(III) nitrate with p-t-butyltetrathiacalix[4]arene in dimethylformamide (dmf) in the presence of base showed a regular, planar cluster of four neodymium atoms bridged by a hydroxyl group to be sandwiched between two fully deprotonated calixarene moieties. The sulfur and oxygen donor atoms of the calixarenes are both involved in coordination to the rare-earth atoms. Both dmf and dmso are found as ligands on neodymium but occupation of the calixarene cavity is by dmf only. The proposed overall stoichiometry of the complex is [Nd4(OH){(p-t-butyltetrathiacalix[4]arene-4H)(dmf)}2(dmf)6(dmso)2](NO3)3.3H2O.

Synthesis of Fused Furans and Thiophenes via Ruthenium-Catalyzed Atom-Transfer [2+2+1] Cycloadditions of α,ω-Diynes

Synlett ◽  
2017 ◽  
Vol 28 (11) ◽  
pp. 1250-1257 ◽  
Author(s):  
Yoshihiko Yamamoto
Keyword(s):  
Natural Products ◽  
Dimethyl Sulfoxide ◽  
Heterocyclic Compounds ◽  
Functional Materials ◽  
Atom Transfer ◽  
Oxygen Donor ◽  
Oxygen Donors

Furans and thiophenes are important five-membered heterocyclic compounds that are found in natural products, functional materials, and pharmaceutics. This account outlines our studies on ruthenium-catalyzed atom-transfer [2+2+1] cycloadditions toward the synthesis of fused furans and thiophenes.1 Introduction2 Synthesis of Furans using Dimethyl Sulfoxide as the Oxygen ­Donor3 Synthesis of 2-Silylfurans Using Nitrones as Oxygen Donors4 Synthesis of Thiophenes Using Thiocarbonyls as Sulfur Donors5 Conclusions

Urticarial reaction to ammonium persulfate

1972 ◽  
Vol 106 (3) ◽  
pp. 413-414 ◽  
Author(s):  
M. M. Brubaker
Keyword(s):  
Ammonium Persulfate

The Effect of Dimethyl Sulfoxide on In Vitro Platelet Function

1976 ◽  
Vol 36 (01) ◽  
pp. 221-229 ◽  
Author(s):  
Charles A. Schiffer ◽  
Caroline L. Whitaker ◽  
Morton Schmukler ◽  
Joseph Aisner ◽  
Steven L. Hilbert
Keyword(s):  
Platelet Count ◽  
Platelet Aggregation ◽  
Dimethyl Sulfoxide ◽  
Platelet Function ◽  
Platelet Volume ◽  
Short Term ◽  
Platelet Factor ◽  
Short Term Exposure ◽  
Structural Abnormalities

SummaryAlthough dimethyl sulfoxide (DMSO) has been used extensively as a cryopreservative for platelets there are few studies dealing with the effect of DMSO on platelet function. Using techniques similar to those employed in platelet cryopreservation platelets were incubated with final concentrations of 2-10% DMSO at 25° C. After exposure to 5 and 10% DMSO platelets remained discoid and electron micrographs revealed no structural abnormalities. There was no significant change in platelet count. In terms of injury to platelet membranes, there was no increased availability of platelet factor-3 or leakage of nucleotides, 5 hydroxytryptamine (5HT) or glycosidases with final DMSO concentrations of 2.5, 5 and 10% DMSO. Thrombin stimulated nucleotide and 5HT release was reduced by 10% DMSO. Impairment of thrombin induced glycosidase release was noted at lower DMSO concentrations and was dose related. Similarly, aggregation to ADP was progressively impaired at DMSO concentrations from 1-5% and was dose related. After the platelets exposed to DMSO were washed, however, aggregation and release returned to control values. Platelet aggregation by epinephrine was also inhibited by DMSO and this could not be corrected by washing the platelets. DMSO-plasma solutions are hypertonic but only minimal increases in platelet volume (at 10% DMSO) could be detected. Shrinkage of platelets was seen with hypertonic solutions of sodium chloride or sucrose suggesting that the rapid transmembrane passage of DMSO prevented significant shifts of water. These studies demonstrate that there are minimal irreversible alterations in in vitro platelet function after short-term exposure to DMSO.

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