scholarly journals Enzymatic Desymmetrization of 19‐ nor ‐Vitamin D 3 A‐Ring Synthon Precursor: Synthesis, Structure Elucidation, and Biological Activity of 1α,25‐Dihydroxy‐3‐ epi ‐19‐ nor ‐vitamin D 3 and 1β,25‐Dihydroxy‐19‐ nor ‐vitamin D 3

2018 ◽  
Vol 360 (14) ◽  
pp. 2762-2772 ◽  
Author(s):  
Tania González‐García ◽  
Annemieke Verstuyf ◽  
Lieve Verlinden ◽  
Susana Fernández ◽  
Miguel Ferrero
Keyword(s):  
Vitamin D ◽  
Biological Activity ◽  
Structure Elucidation ◽  
Precursor Synthesis ◽  
Enzymatic Desymmetrization ◽  
Vitamin D 3

Vitamin D Provision in High-Yield Dairy Cows During the Winter Housing Period

2014 ◽  
Vol 1 (1) ◽  
pp. 42-46
Author(s):  
L. Yuskiv ◽  
V. Vlizlo
Keyword(s):  
Vitamin D ◽  
Alkaline Phosphatase Level ◽  
Mineral Metabolism ◽  
Physiological State ◽  
Blood Parameters ◽  
Postnatal Period ◽  
High Yield ◽  
Oral Supplementation ◽  
Calcium Phosphorus ◽  
Vitamin D 3

Aim. To investigate the vitamin D status in highly productive cows during winter housing period and effect of cholecalciferol by various ways of vitamin D 3 injection to cows in last days of gestation and after calving. Methods. Enzyme-linked immunoassay, spectrophotometry. Results. It has been stated that intramuscular injection of cholecalciferol into cows caused increase of the vitamin D 3 active metabolite – 25-OHD 3 , calcium, phosphorus and magnesium levels together with decrease of alkaline phosphatase level in pre- and post-natal periods. Oral supplementation makes little infl uence on the studied blood parameters of cows. Conclusions. Extrabuccal administration and oral supplementation of cholecalciferol in winter housing period to high-yield cows in the last days of gestation and after calving is accompanied by increased levels of its metabolites and their effect on mineral metabolism in the postnatal period. The nature of these changes depends on the mode of vitamin D administration and the physiological state of the cows.

scholarly journals New Haloterpenes from the Marine Red Alga Laurencia papillosa: Structure Elucidation and Biological Activity

Marine Drugs ◽  
2021 ◽  
Vol 19 (1) ◽  
pp. 35
Author(s):  
Mohamed Shaaban ◽  
Ghada S. E. Abou-El-Wafa ◽  
Christopher Golz ◽  
Hartmut Laatsch
Keyword(s):  
Biological Activity ◽  
Crude Extract ◽  
Structure Elucidation ◽  
Antimicrobial Activities ◽  
Red Alga ◽  
Spectroscopic Methods ◽  
X Ray Diffraction ◽  
X Ray ◽  
Chemical Structures ◽  
Terpene Derivatives

Analysis of the air-dried marine red alga Laurencia papillosa, collected near Ras-Bakr at the Suez gulf (Red Sea) in Egypt delivered five new halogenated terpene derivatives: aplysiolic acid (1), 7-acetyl-aplysiol (2), aplysiol-7-one (3), 11,14-dihydroaplysia-5,11,14,15-tetrol (5a), and a new maneonene derivative 6, named 5-epi-maneolactone. The chemical structures of these metabolites were characterized employing spectroscopic methods, and the relative and absolute configurations were determined by comparison of experimental and ab initio-calculated NMR, NOE, ECD, and ORD data, and by X-ray diffraction of 2 and 6. The antimicrobial activities of the crude extract and compounds 1–3, 5a and 6 were studied.

scholarly journals Biological activity of 24,24-difluoro-25-hydroxyvitamin D3. Effect of blocking of 24-hydroxylation on the functions of vitamin D.

1979 ◽  
Vol 254 (15) ◽  
pp. 7163-7167
Author(s):  
Y Tanaka ◽  
H F DeLuca ◽  
Y Kobayashi ◽  
T Taguchi ◽  
N Ikekawa ◽  
...  
Keyword(s):  
Vitamin D ◽  
Biological Activity

scholarly journals Isolation, Structure Elucidation, and Biological Activity of a New Alkaloid from Zanthoxylum rhetsa

2011 ◽  
Vol 6 (11) ◽  
pp. 1934578X1100601
Author(s):  
Karsten Krohn ◽  
Stephan Cludius-Brandt ◽  
Barbara Schulz ◽  
Mambatta Sreelekha ◽  
Pottachola Mohamed Shafi
Keyword(s):  
Biological Activity ◽  
Carboxylic Acid ◽  
Medicinal Plant ◽  
Plant Extract ◽  
Structure Elucidation ◽  
Biologically Active ◽  
Reduction Product ◽  
Pharmacological Properties ◽  
Evergreen Tree

Several biologically active alkaloids (1-4, 6), including a new quinazoline-6-carboxylic acid (1), were isolated from the medicinal plant Zanthoxylum rhetsa, an evergreen tree, native to subtropical areas. Whereas the pharmacological properties of the plant extract and single constituents have been widely tested, we now show that all of the metabolites have antialgal activities, all but 6 are antibacterial, and 6 and the reduction product 5 (derived from 4) are also antifungal.

The Effects of Diphosphonate on the Metabolism and Biological Activity of Vitamin D

1972 ◽  
Vol 42 (4) ◽  
pp. 16P-16P ◽  
Author(s):  
L. F. Hill ◽  
E. B. Mawer ◽  
G. A. Lumb ◽  
S. W. Stanbury
Keyword(s):  
Vitamin D ◽  
Biological Activity
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