Asymmetric Hydrogenation of 3-Amido-2-arylpyridinium Salts by Triply Chloride-Bridged Dinuclear Iridium Complexes Bearing Enantiopure Diphosphine Ligands: Synthesis of Neurokinin-1 Receptor Antagonist Derivatives

2016 ◽  
Vol 358 (12) ◽  
pp. 1929-1933 ◽  
Author(s):  
Atsuhiro Iimuro ◽  
Kosuke Higashida ◽  
Yusuke Kita ◽  
Kazushi Mashima
Keyword(s):  
Receptor Antagonist ◽  
Asymmetric Hydrogenation ◽  
Diphosphine Ligands ◽  
Iridium Complexes ◽  
Neurokinin 1 Receptor ◽  
Neurokinin 1

An FDA Approved Neurokinin-1 Receptor Antagonist is Effective in Reducing Intraabdominal Adhesions when Administered Intraperitoneally, But Not Orally

2008 ◽  
Vol 12 (10) ◽  
pp. 1754-1761 ◽  
Author(s):  
Rizal Lim ◽  
Jonathan M. Morrill ◽  
Scott G. Prushik ◽  
Karen L. Reed ◽  
Adam C. Gower ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Neurokinin 1 Receptor ◽  
Intraabdominal Adhesions ◽  
Neurokinin 1

Antitumoral action of the neurokinin-1 receptor antagonist L-733 060 on human melanoma cell lines

2004 ◽  
Vol 14 (3) ◽  
pp. 183-188 ◽  
Author(s):  
Miguel Mu??oz ◽  
Ana P??rez ◽  
Marisa Rosso ◽  
Carmen Zamarriego ◽  
Rosario Rosso
Keyword(s):  
Receptor Antagonist ◽  
Cell Lines ◽  
Melanoma Cell ◽  
Human Melanoma ◽  
Human Melanoma Cell ◽  
Neurokinin 1 Receptor ◽  
Neurokinin 1 ◽  
Antitumoral Action ◽  
Melanoma Cell Lines

Synthesis of the Neurokinin 1 Receptor Antagonist (+)-L-733,060 by Jacobsen’s Hydrolytic Kinetic Resolution

2020 ◽  
Vol 56 (12) ◽  
pp. 2159-2164
Author(s):  
D. N. Bhangare ◽  
V. B. Mahale ◽  
R. G. Shinde ◽  
M. D. Nikalje ◽  
S. D. Duthade ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Kinetic Resolution ◽  
Neurokinin 1 Receptor ◽  
Hydrolytic Kinetic Resolution ◽  
Neurokinin 1
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