Palladium-Catalyzed One-Pot Consecutive Amination and Sonogashira Coupling for Selective Synthesis of 2-Alkynylanilines

2015 ◽  
Vol 357 (14-15) ◽  
pp. 3052-3056 ◽  
Author(s):  
Shanfei Pan ◽  
Xueji Ma ◽  
Danni Zhong ◽  
Wanzhi Chen ◽  
Miaochang Liu ◽  
...  
ChemInform ◽  
2016 ◽  
Vol 47 (8) ◽  
pp. no-no
Author(s):  
Shanfei Pan ◽  
Xueji Ma ◽  
Danni Zhong ◽  
Wanzhi Chen ◽  
Miaochang Liu ◽  
...  

Synthesis ◽  
2017 ◽  
Vol 49 (23) ◽  
pp. 5149-5158
Author(s):  
Alavala Krishna Reddy ◽  
Gedu Satyanarayana

Palladium-catalyzed copper-free Sonogashira coupling of 2-bromocarbonyls is presented. This method afforded the 2-alkynylaryl carbonyls, useful synthons for the accomplishment of many carbocyclic and heterocyclic motifs. Significantly, the strategy was extended to the one-pot synthesis of isobenzofurans via reduction followed by intramolecular 5-exo-dig cyclization.


ChemCatChem ◽  
2021 ◽  
Author(s):  
Huanfeng Jiang ◽  
Wenfang Xiong ◽  
Bowen Wu ◽  
Baiyao Zhu ◽  
Xiaobin Tan ◽  
...  

2019 ◽  
Vol 17 (17) ◽  
pp. 4281-4290 ◽  
Author(s):  
Hitesh Kumar Saini ◽  
Shiv Dhiman ◽  
Nitesh Kumar Nandwana ◽  
Rangan Krishnan ◽  
Anil Kumar

A highly efficient protocol has been developed for the synthesis of diversely substituted isoindolo[2,1-b]isoquinolin-7(5H)-ones through sequential Cu(ii)-catalyzed Sonogashira coupling, intramolecular hydroamidation followed by palladium-catalyzed ligand free Heck reaction.


2017 ◽  
Vol 15 (17) ◽  
pp. 3674-3680 ◽  
Author(s):  
Shenghai Guo ◽  
Jianhui Zhai ◽  
Fang Wang ◽  
Xuesen Fan

An efficient route to 6,6a-dihydroisoindolo[2,1-a]quinazoline-5,11-diones via Pd-catalyzed carbonylative cyclization of 2-aminobenzamides with 2-bromobenzaldehydes and CO is reported.


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