Gold(I)-Catalyzed Tandem Reaction ofγ-Amino-Substituted Propargylic Esters to Pyrrolines and its Application in the Formal Synthesis of (±)-Aphanorphine

2015 ◽  
Vol 357 (9) ◽  
pp. 2082-2088 ◽  
Author(s):  
Zhengshen Wang ◽  
Huaiji Zheng ◽  
Juan Yang ◽  
Xingang Xie ◽  
Xuegong She
Author(s):  
Xin-Ming Xu ◽  
Ming Xie ◽  
Jiazhu Li ◽  
Mei-Xiang Wang

An exquisite Pybox/Cu(OTf)2-catalyzed asymmetric tandem reaction of tertiary enamides was developed, which enabled the expeditious synthesis of indolizino[8,7-b]indole derivatives in high yield, excellent enantioselectivity and diastereoselectivity.


Author(s):  
Prakash T. Parvatkar ◽  
Perunninakulath S. Parameswaran ◽  
Debasish Bandyopadhyay ◽  
Sanghamitra Mukherjee ◽  
Bimal K. Banik

Synthesis ◽  
2021 ◽  
Author(s):  
Fengtao Zhou ◽  
Qiuyu Zhang ◽  
Kashif Majeed ◽  
Bangjie Liu

AbstractA copper-catalyzed tandem reaction has been developed for the synthesis of 1,2,3-triazole-fused indole derivatives. This protocol allowed us to access a wide range of 1,2,3-triazole-fused indole derivatives in moderate to excellent yields. The 1,2,3-triazole-fused indole derivatives emit blue and greenish light when excited at 365 nm. The products were further explored for their quantum efficiency and photophysical properties.


2021 ◽  
Author(s):  
Sepideh Hayatgheybi ◽  
Hormoz Khosravi ◽  
Hossein Zahedian Tejeneki ◽  
Frank Rominger ◽  
Hamid Reza Bijanzadeh ◽  
...  
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2021 ◽  
Author(s):  
Mengxue Lu ◽  
Zongli Xiong ◽  
Yuqiao Zhou ◽  
Xin Wang ◽  
Xiaoyi Li ◽  
...  

The enantioselective synthesis of fluorinated tricyclic chromanones with multiple vicinal stereogenic centers has been realized for the first time, through the tandem reaction between 2-fluorinated 1-(2-hydroxyaryl)-1,3-diketones and α,β-unsaturated aldehydes. In...


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