Hydrogel Microelectromechanical System (MEMS) Resonators: Beyond Cost-Effective Sensing Platform

2019 ◽  
Vol 4 (3) ◽  
pp. 1800597 ◽  
Author(s):  
Yeowon Yoon ◽  
Inseok Chae ◽  
Thomas Thundat ◽  
Jungchul Lee
Keyword(s):  
Cost Effective ◽  
Microelectromechanical System ◽  
Mems Resonators ◽  
Sensing Platform

scholarly journals A Novel Cesaro Fractal EBG-based Sensing Platform for Dielectric Characterization of Liquids

2020 ◽  
Author(s):  
Muhammad Zubair ◽  
Muhammad Qasim Mehmood ◽  
Kashif Riaz ◽  
Amna Zubair ◽  
Ali Arif
Keyword(s):  
Cost Effective ◽  
Good Precision ◽  
Dielectric Characterization ◽  
Sensing Applications ◽  
Sensing Platform ◽  
Dielectric Constant And Loss ◽  
Increased Sensitivity ◽  
Rms Error ◽  
Measured Sensitivity

<p>This paper presents a compact, cost-effective, and contactless fractal modified EBG-based microwave sensing platform for dielectric characterization of liquids by analyzing the variation in the reflection coefficient of an antenna. The reported design is composed of a triangular-shaped antenna (0.323λ­<sub>o </sub>x 0.323λ­<sub>o</sub>) placed over a 3 x 3 array of Cesaro fractal based EBG plane (0.7λ­<sub>o</sub> x 0.7λ­<sub>o</sub>) operating at 2.45 GHz. A significant enhancement of the E-field in the sensing region has been achieved with the incorporation of Cesaro fractals in the EBG plane which results in increased sensitivity and compactness. To validate its performance, absolute solutions of butan-1-ol, methanol, and water are loaded, and a maximum measured sensitivity of 0.875% and a maximum quality factor of 90.05 is achieved. Moreover, a maximum RMS error in retrieved values of dielectric constant and loss tangent of liquid under test is found to be 1.092% and 0.813%, respectively. Our demonstrated EBG-based sensor has a compact footprint with good precision, affordability, and ease of operation in detecting liquids for microwave sensing applications. </p><p><br></p>

Development of Synergistic Opto-Electronic Sensing Platform based on Zinc Oxide Semiconducting Nanostructures

2012 ◽  
Vol 2012 (1) ◽  
pp. 001191-001196
Author(s):  
Anurag Gupta ◽  
Bruce C. Kim ◽  
Mitchell Spryn ◽  
Eugene Edwards ◽  
Christina Brantley ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Cost Effective ◽  
Zinc Oxide Nanowires ◽  
Oxide Nanowires ◽  
Sensing Platform ◽  
Sensor Platform ◽  
Semiconducting Nanostructures ◽  
Ft Ir ◽  
Characterization Studies ◽  
Electronic Sensing

Potential of zinc oxide nanowires for developing a sensitive opto-electronic platform was demonstrated. Zinc oxide nanowires synthesized on insulating sapphire substrates were functionalized with an optically active receptor, 1-pyrenebutyric acid. Appropriate characterization studies including XPS and FT-IR ATR are reported. I-V curves of pristine and receptor-modified nanowires were utilized to highlight the potential of zinc oxide nano-heterostructures for developing a sensitive opto-electronic platform for p-nitrophenol sensing. Packaging issues for achieving an efficient and cost-effective sensor platform have also been outlined.

Inline biofilm monitoring based on near-infrared spectroscopy with ultracompact spectrometer technology

NIR news ◽  
2020 ◽  
Vol 31 (7-8) ◽  
pp. 9-13
Author(s):  
Robert Zimmerleiter ◽  
Elisabeth Leiss-Holzinger ◽  
Eva Maria Wagner ◽  
Kathrin Kober-Rychli ◽  
Martin Wagner ◽  
...  
Keyword(s):  
Near Infrared ◽  
Spectral Response ◽  
Principal Component ◽  
Cost Effective ◽  
Sensor Surface ◽  
Chain Reaction ◽  
Microelectromechanical System ◽  
Infrared Spectral ◽  
Infrared Measurement ◽  
Polymerase Chain

In this article, we demonstrate a promising inline near-infrared measurement scheme for 24/7 biofilm monitoring based on cost-effective microelectromechanical system-based spectrometer technology. The shown near-infrared spectral data, acquired at a beer-canning line during a representative time span of 10 days, are analyzed by means of principal component analysis and the performance of the monitoring system and its capability to identify biofilms on its sensor surface are investigated by comparing spectral response with results of offline polymerase chain reaction measurements of smear samples. Correlations between presence of a biofilm and its thickness with scores on PC1 and PC2, respectively, were observed.

Ultrasensitive detection of nitroexplosive – picric acid via a conjugated polyelectrolyte in aqueous media and solid support

2015 ◽  
Vol 51 (33) ◽  
pp. 7207-7210 ◽  
Author(s):  
Sameer Hussain ◽  
Akhtar Hussain Malik ◽  
Mohammad Adil Afroz ◽  
Parameswar Krishnan Iyer
Keyword(s):  
Electrostatic Interactions ◽  
Picric Acid ◽  
Aqueous Media ◽  
Chitosan Film ◽  
Cost Effective ◽  
Paper Strip ◽  
Contact Mode ◽  
Conjugated Polyelectrolyte ◽  
Sensing Platform ◽  
Strip Test

Cationic polymer PMI detects picric acid at ppt levels via combination of ground state charge transfer, RET and electrostatic interactions. A paper strip test and a contact mode sensing platform using chitosan film confirm the method as simple, portable and cost-effective.

scholarly journals Microwave Spoof Surface Plasmon Polariton-Based Sensor for Ultrasensitive Detection of Liquid Analyte Dielectric Constant

Sensors ◽  
2021 ◽  
Vol 21 (16) ◽  
pp. 5477
Author(s):  
Ivana Podunavac ◽  
Vasa Radonic ◽  
Vesna Bengin ◽  
Nikolina Jankovic
Keyword(s):  
Dielectric Constant ◽  
Surface Plasmon ◽  
Edible Oils ◽  
Low Cost ◽  
High Sensitivity ◽  
Cost Effective ◽  
Ultrasensitive Detection ◽  
Sensing Platform ◽  
Excellent Candidate ◽  
Plasmon Polaritons

In this paper, a microwave microfluidic sensor based on spoof surface plasmon polaritons (SSPPs) was proposed for ultrasensitive detection of dielectric constant. A novel unit cell for the SSPP structure is proposed and its behaviour and sensing potential analysed in detail. Based on the proposed cell, the SSPP microwave structure with a microfluidic reservoir is designed as a multilayer configuration to serve as a sensing platform for liquid analytes. The sensor is realized using a combination of rapid, cost-effective technologies of xurography, laser micromachining, and cold lamination bonding, and its potential is validated in the experiments with edible oil samples. The results demonstrate high sensitivity (850 MHz/epsilon unit) and excellent linearity (R2 = 0.9802) of the sensor, which, together with its low-cost and simple fabrication, make the proposed sensor an excellent candidate for the detection of small changes in the dielectric constant of edible oils and other liquid analytes.

scholarly journals Development of RNA-based assay for rapid detection of SARS-CoV-2 in clinical samples

2020 ◽  
Author(s):  
Vinod Kumar ◽  
Suman Mishra ◽  
Rajni Sharma ◽  
Jyotsana Agarwal ◽  
Ujjala Ghoshal ◽  
...  
Keyword(s):  
Colorimetric Assay ◽  
Cost Effective ◽  
Clinical Samples ◽  
Visible Range ◽  
Gold Colloid ◽  
Rt Pcr ◽  
Sensing Platform ◽  
Effective Manner ◽  
The Subject ◽  
Induced Aggregation

AbstractThe ongoing spread of pandemic coronavirus disease (COVID-19) is caused by Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2). In the lack of specific drugs or vaccines for SARS-CoV-2, demands rapid diagnosis and management are crucial for controlling the outbreak in the community. Here we report the development of the first rapid-colorimetric assay capable of detecting SARS-CoV-2 in the human nasopharyngeal RNA sample in less than 30 minutes. We utilized a nanomaterial-based optical sensing platform to detect RNA-dependent RNA polymerase (RdRp) gene of SARS-CoV-2, where the formation of oligo probe-target hybrid led to salt-induced aggregation and changes in gold-colloid color from pink to blue in visible range. Accordingly, we found a change in colloid color from pink to blue in assay containing nasopharyngeal RNA sample from the subject with clinically diagnosed COVID-19. The colloid retained pink color when the test includes samples from COVID-19 negative subjects or human papillomavirus (HPV) infected women. The results were validated using nasopharangeal RNA samples from suspected COVID-19 subjects (n=136). Using RT-PCR as gold standard, the assay was found to have 85.29% sensitivity and 94.12% specificity. The optimized method has detection limit as little as 0.5 ng of SARS-CoV-2 RNA. Overall, the developed assay rapidly detects SARS-CoV-2 RNA in clinical samples in a cost-effective manner and would be useful in pandemic management by facilitating mass screening.

scholarly journals Development of a Cost-Effective Sensing Platform for Monitoring Phosphate in Natural Waters

Chemosensors ◽  
2018 ◽  
Vol 6 (4) ◽  
pp. 57 ◽  
Author(s):  
Andrew Donohoe ◽  
Gareth Lacour ◽  
Peter McCluskey ◽  
Dermot Diamond ◽  
Margaret McCaul
Keyword(s):  
Natural Waters ◽  
Limit Of Detection ◽  
Low Cost ◽  
Unit Cost ◽  
High Standard ◽  
Cost Effective ◽  
Remote Access ◽  
Sampling Location ◽  
Sensing Platform

A sensing platform for the in situ, real-time analysis of phosphate in natural waters has been realised using a combination of microfluidics, colorimetric reagent chemistries, low-cost LED-based optical detection and wireless communications. Prior to field deployment, the platform was tested over a period of 55 days in the laboratory during which a total of 2682 autonomous measurements were performed (854 each of sample, high standard and baseline, and 40 × 3 spiked solution measurements). The platform was subsequently field-deployed in a freshwater stream at Lough Rea, Co., Galway, Ireland, to track changes in phosphate over a five day period. During this deployment, 165 autonomous measurements (55 each of sample, high standard, and baseline) were performed and transmitted via general packet radio service (GPRS) to a web interface for remote access. Increases in phosphate levels at the sampling location coincident with rainfall events (min 1.45 µM to max 10.24 µM) were detected during the deployment. The response was found to be linear up to 50 µM PO43−, with a lower limit of detection (LOD) of 0.09 µM. Laboratory and field data suggest that despite the complexity of reagent-based analysers, they are reasonably reliable in remote operation, and offer the best opportunity to provide enhanced in situ chemical sensing capabilities. Modifications that could further improve the reliability and scalability of these platforms while simultaneously reducing the unit cost are discussed.

scholarly journals A Fluorescence Inner-Filter Effect Based Sensing Platform for Turn-On Detection of Glutathione in Human Serum

Sensors ◽  
2019 ◽  
Vol 19 (2) ◽  
pp. 228 ◽  
Author(s):  
Shurong Tang ◽  
Xiuhua You ◽  
Quanhui Fang ◽  
Xin Li ◽  
Guangwen Li ◽  
...  
Keyword(s):  
Human Serum ◽  
Limit Of Detection ◽  
Cost Effective ◽  
Inner Filter Effect ◽  
Disease Diagnosis ◽  
Fluorescent Properties ◽  
Serum Samples ◽  
Turn On ◽  
Filter Effect ◽  
Sensing Platform

A novel turn-on fluorescence assay was developed for the rapid detection of glutathione (GSH) based on the inner-filter effect (IFE) and redox reaction. Molybdenum disulfide quantum dots (MoS2 QDs), which have stable fluorescent properties, were synthesized with hydrothermal method. Manganese dioxide nanosheets (MnO2 NSs) were prepared by exfoliating the bulk δ-MnO2 material in bovine serum albumin (BSA) aqueous solution. The morphology structures of the prepared nanoparticles were characterized by transmission electron microscope (TEM). Studies have shown that the fluorescence of MoS2 QDs could be quenched in the presence of MnO2 NSs as a result of the IFE, and is recovered after the addition of GSH to dissolve the MnO2 NSs. The fluorescence intensity showed a good linear relationship with the GSH concentration in the range 20–2500 μM, the limit of detection was 1.0 μM. The detection method was applied to the analysis of GSH in human serum samples. This simple, rapid, and cost-effective method has great potential in analyzing GSH and in disease diagnosis.

scholarly journals Optimization of Apta-Sensing Platform for Detection of Prostate Cancer Marker PCA3

2021 ◽  
Vol 22 (23) ◽  
pp. 12701
Author(s):  
Sarra Takita ◽  
Alexei Nabok ◽  
Anna Lishchuk ◽  
David Smith
Keyword(s):  
Prostate Cancer ◽  
Total Internal Reflection ◽  
Covalent Binding ◽  
High Specificity ◽  
Cost Effective ◽  
Affinity Constant ◽  
Cyclic Voltammograms ◽  
Sensing Platform ◽  
Low Concentrations ◽  
Rna Transcript

This work is a continuation of our research into the development of simple, reliable, and cost-effective methods for the early diagnosis of prostate cancer (PCa). The proposed method is based on the electrochemical detection of the PCA3 biomarker of PCa (long non-coded RNA transcript expressed in urine) using a specific aptamer labeled with a redox group (methylene blue). The electrochemical measurements (cyclic voltammograms) obtained from electrodes functionalized with the aptamer were complemented in this work by another biosensing technique: total internal reflection ellipsometry (TIRE). In addition to proving the concept of the detection of PCA3 in low concentrations down to 90 pM, this study improved our understanding of the processes by which PCA3 binds to its specific aptamer. The high specificity of the binding of PCA3 to the aptamer was assessed by studying the binding kinetics, which yielded an affinity constant (KD) of 2.58 × 10−9 M. Additional XPS measurements confirmed the strong covalent binding of aptamers to gold and showed spectral features associated with PCA3 to aptamer binding.

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