Optimizing Process Parameters in Commercial Micro-Stereolithography for Forming Emulsions and Polymer Microparticles in Nonplanar Microfluidic Devices

2018 ◽  
Vol 4 (1) ◽  
pp. 1800408 ◽  
Author(s):  
Max J. Männel ◽  
Lukas Selzer ◽  
Ricardo Bernhardt ◽  
Julian Thiele
Keyword(s):  
Process Parameters ◽  
Microfluidic Devices ◽  
Polymer Microparticles

scholarly journals Effect of Process Parameters and Material Properties on Laser Micromachining of Microchannels

Micromachines ◽  
2019 ◽  
Vol 10 (2) ◽  
pp. 123 ◽  
Author(s):  
Matthew Benton ◽  
Mohammad Hossan ◽  
Prashanth Konari ◽  
Sanjeewa Gamagedara
Keyword(s):  
Process Parameters ◽  
Laser System ◽  
Three Dimensional ◽  
Microfluidic Devices ◽  
Scanning Speed ◽  
Transient Heat Conduction ◽  
Laser Micromachining ◽  
Rapid Phase ◽  
Widespread Application ◽  
Optimization Of Process Parameters

Laser micromachining has emerged as a promising technique for mass production of microfluidic devices. However, control and optimization of process parameters, and design of substrate materials are still ongoing challenges for the widespread application of laser micromachining. This article reports a systematic study on the effect of laser system parameters and thermo-physical properties of substrate materials on laser micromachining. Three dimensional transient heat conduction equation with a Gaussian laser heat source was solved using finite element based Multiphysics software COMSOL 5.2a. Large heat convection coefficients were used to consider the rapid phase transition of the material during the laser treatment. The depth of the laser cut was measured by removing material at a pre-set temperature. The grid independent analysis was performed for ensuring the accuracy of the model. The results show that laser power and scanning speed have a strong effect on the channel depth, while the level of focus of the laser beam contributes in determining both the depth and width of the channel. Higher thermal conductivity results deeper in cuts, in contrast the higher specific heat produces shallower channels for a given condition. These findings can help in designing and optimizing process parameters for laser micromachining of microfluidic devices.

Microfluidics as a tool to assess and induce emulsion destabilization

Soft Matter ◽  
2022 ◽  
Author(s):  
Tatiana Porto Santos ◽  
Cesare Mikhail Cejas ◽  
Rosiane Lopes da Cunha
Keyword(s):  
Process Parameters ◽  
Microfluidic Devices ◽  
Length Scale ◽  
Small Length ◽  
Small Length Scale ◽  
Emulsion Droplets ◽  
Microfluidic Technology

Microfluidic technology enables a judicious control of the process parameters on a small length-scale, which in turn allows speeding up the destabilization of emulsion droplets interface in microfluidic devices. In...

Effects of Process Parameters on Direct Deposition Hydrogel Molding for the Fabrication Microfluidic Devices

2016 ◽  
Author(s):  
Karen Chang Yan ◽  
John Sperduto ◽  
Christopher Civitello ◽  
Alison McCarthy ◽  
Aren Moy
Keyword(s):  
Process Parameters ◽  
Electrospun Fiber ◽  
Base Material ◽  
Microfluidic Devices ◽  
Direct Writing ◽  
Channel Diameter ◽  
Curing Conditions ◽  
Direct Deposition ◽  
Method Effects ◽  
And Control

Advantages of microfluidic devices include miniaturization, easy of integration, small reagent consumption etc., and have led to the wide applications in biomedical field. Fabrication of microfluidic devices is commonly done through microfabrication methods; microfabication-free/using rapid prototyping methods have also been developed in recent years to enable applications of microfluidic devices to a broader range. Our recent study has demonstrated the feasibility of fabricating electrospun fiber embedded microfluidic devices by integrating hydrogel molding and electrospinning (ES) through a multi-layer construction process. This paper focuses on examining how process parameters affect microchannel formation in microfluidic devices fabricated using direct-deposition hydrogel molding (dHGM). PDMS (polydimethylsiloxane) was chosen as the base-material of the device, and Agarose hydrogel was used to generate the mold channels. A direct writing system was used to deposit the hydrogel mold. We examined three parameters affecting the dHGM based microchannel formation: hydrogel composition, curing conditions, and deposition method. Effects of these parameters were characterized in terms of ease-of-handling, consistent channel formation, and control of channel diameter.

High-Speed Fabrication of Microchannels Using Line-Based Laser Induced Plasma Micromachining

2015 ◽  
Vol 3 (2) ◽  
Author(s):  
Ishan Saxena ◽  
Rajiv Malhotra ◽  
Kornel Ehmann ◽  
Jian Cao
Keyword(s):  
Process Parameters ◽  
Optical System ◽  
Pulse Energy ◽  
High Speed ◽  
Microfluidic Devices ◽  
Pulse Frequency ◽  
Free Form ◽  
Laser Induced Plasma ◽  
Circular Spot ◽  
Energy Pulse

Microtexturing of surfaces has various applications that often involve texturing over large (macroscale) areas with high precision and resolution. This demands scalability and speed of texturing while retaining feature sizes of the order of a few microns. Microchannels are a versatile microfeature, which are often used in microfluidic devices and can be arrayed or joined to form patterns and free-form geometries. We present a technique to fabricate microchannels on surfaces with high-speed and by using a multimaterial process, namely, laser induced plasma micromachining (LIPMM). The process has the potential to machine metals, ceramics, polymers, and other transparent, brittle, and hard-to-machine materials. The presented technique uses an optical system to modify the laser spot into the shape of a line, to fabricate microchannels directly without scanning as in the case of a regular circular spot. The process schematics are shown, and micromachining experiments on polished aluminum are discussed. Moreover, it is shown that the depth and width of the channels may be varied by changing process parameters like the pulse energy, pulse frequency, and number of exposures.

Effects of Fabrication Process Parameters on the Properties of Cyclic Olefin Copolymer Microfluidic Devices

2006 ◽  
Vol 15 (5) ◽  
pp. 1060-1068 ◽  
Author(s):  
C.K. Fredrickson ◽  
Z. Xia ◽  
C. Das ◽  
R. Ferguson ◽  
F.T. Tavares ◽  
...  
Keyword(s):  
Process Parameters ◽  
Microfluidic Devices ◽  
Fabrication Process ◽  
Cyclic Olefin Copolymer ◽  
Cyclic Olefin
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