scholarly journals Neural Regeneration: Efficient Delivery of Nerve Growth Factors to the Central Nervous System for Neural Regeneration (Adv. Mater. 33/2019)

2019 ◽  
Vol 31 (33) ◽  
pp. 1970233 ◽  
Author(s):  
Duo Xu ◽  
Di Wu ◽  
Meng Qin ◽  
Lina R. Nih ◽  
Chaoyong Liu ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Growth Factors ◽  
Neural Regeneration ◽  
Nerve Growth ◽  
Efficient Delivery ◽  
Nerve Growth Factors ◽  
The Central Nervous System

Efficient Delivery of Nerve Growth Factors to the Central Nervous System for Neural Regeneration

2019 ◽  
Vol 31 (33) ◽  
pp. 1900727 ◽  
Author(s):  
Duo Xu ◽  
Di Wu ◽  
Meng Qin ◽  
Lina R. Nih ◽  
Chaoyong Liu ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Growth Factors ◽  
Neural Regeneration ◽  
Nerve Growth ◽  
Efficient Delivery ◽  
Nerve Growth Factors ◽  
The Central Nervous System

Nerve Growth Factor (NGF) in the Central Nervous System: Implications for the Treatment of Alzheimer’s Disease

Brain Repair ◽  
1990 ◽  
pp. 99-112
Author(s):  
Dan Lindholm ◽  
Christine Bandtlow ◽  
Matthias Spranger ◽  
Bastian Hengerer ◽  
Michael Meyer ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Central Nervous System ◽  
Nervous System ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Nerve Growth ◽  
The Central Nervous System

scholarly journals Death of developing neurons: New insights and implications for connectivity

2013 ◽  
Vol 203 (3) ◽  
pp. 385-393 ◽  
Author(s):  
Martijn P.J. Dekkers ◽  
Vassiliki Nikoletopoulou ◽  
Yves-Alain Barde
Keyword(s):  
Central Nervous System ◽  
Cell Death ◽  
Nervous System ◽  
Growth Factors ◽  
Axonal Degeneration ◽  
Neuronal Development ◽  
Critical Role ◽  
Synaptic Function ◽  
The Central Nervous System ◽  
Developing Neurons

The concept that target tissues determine the survival of neurons has inspired much of the thinking on neuronal development in vertebrates, not least because it is supported by decades of research on nerve growth factor (NGF) in the peripheral nervous system (PNS). Recent discoveries now help to understand why only some developing neurons selectively depend on NGF. They also indicate that the survival of most neurons in the central nervous system (CNS) is not simply regulated by single growth factors like in the PNS. Additionally, components of the cell death machinery have begun to be recognized as regulators of selective axonal degeneration and synaptic function, thus playing a critical role in wiring up the nervous system.

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