scholarly journals Muscle Degeneration: Preparation of Stretchable Nanofibrous Sheets with Sacrificial Coaxial Electrospinning for Treatment of Traumatic Muscle Injury (Adv. Healthcare Mater. 8/2021)

2021 ◽  
Vol 10 (8) ◽  
pp. 2170041
Author(s):  
Oanh‐Vu Pham‐Nguyen ◽  
Young Ju Son ◽  
Tae‐wan Kwon ◽  
Junhyung Kim ◽  
Yun Chan Jung ◽  
...  
Keyword(s):  
Muscle Injury ◽  
Coaxial Electrospinning ◽  
Muscle Degeneration

scholarly journals Necdin mediates skeletal muscle regeneration by promoting myoblast survival and differentiation

2007 ◽  
Vol 179 (2) ◽  
pp. 305-319 ◽  
Author(s):  
Daniela Deponti ◽  
Stéphanie François ◽  
Silvia Baesso ◽  
Clara Sciorati ◽  
Anna Innocenzi ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Transgenic Mice ◽  
Satellite Cell ◽  
Muscle Regeneration ◽  
Muscle Injury ◽  
Muscle Fibers ◽  
Skeletal Muscle Regeneration ◽  
Muscle Degeneration ◽  
Wild Type ◽  
Cell Type

Regeneration of muscle fibers that are lost during pathological muscle degeneration or after injuries is sustained by the production of new myofibers. An important cell type involved in muscle regeneration is the satellite cell. Necdin is a protein expressed in satellite cell–derived myogenic precursors during perinatal growth. However, its function in myogenesis is not known. We compare transgenic mice that overexpress necdin in skeletal muscle with both wild-type and necdin null mice. After muscle injury the necdin null mice show a considerable defect in muscle healing, whereas mice that overexpress necdin show a substantial increase in myofiber regeneration. We also find that in muscle, necdin increases myogenin expression, accelerates differentiation, and counteracts myoblast apoptosis. Collectively, these data clarify the function and mechanism of necdin in skeletal muscle and show the importance of necdin in muscle regeneration.

Preparation of Stretchable Nanofibrous Sheets with Sacrificial Coaxial Electrospinning for Treatment of Traumatic Muscle Injury

2021 ◽  
pp. 2002228
Author(s):  
Oanh‐Vu Pham‐Nguyen ◽  
Young Ju Son ◽  
Tae‐wan Kwon ◽  
Junhyung Kim ◽  
Yun Chan Jung ◽  
...  
Keyword(s):  
Muscle Injury ◽  
Coaxial Electrospinning

scholarly journals α1-Syntrophin Gene Disruption Results in the Absence of Neuronal-type Nitric-oxide Synthase at the Sarcolemma but Does Not Induce Muscle Degeneration

1999 ◽  
Vol 274 (4) ◽  
pp. 2193-2200 ◽  
Author(s):  
Shuhei Kameya ◽  
Yuko Miyagoe ◽  
Ikuya Nonaka ◽  
Takaaki Ikemoto ◽  
Makoto Endo ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Gene Disruption ◽  
Muscle Degeneration ◽  
Oxide Synthase ◽  
Neuronal Type

scholarly journals Stem Cells for the Treatment of Skeletal Muscle Injury

2009 ◽  
Vol 28 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Andres J. Quintero ◽  
Vonda J. Wright ◽  
Freddie H. Fu ◽  
Johnny Huard
Keyword(s):  
Skeletal Muscle ◽  
Stem Cells ◽  
Muscle Injury ◽  
Skeletal Muscle Injury

Histochemical assessment of cytochrome oxidase activity for monitoring ischemic muscle injury

1985 ◽  
Vol 88 (2) ◽  
pp. 265-276 ◽  
Author(s):  
Richard M. Millis ◽  
Theodore A. Stephens ◽  
Gerard Harris ◽  
Columbus Anonye ◽  
Michael Reynolds
Keyword(s):  
Cytochrome Oxidase ◽  
Oxidase Activity ◽  
Muscle Injury ◽  
Cytochrome Oxidase Activity ◽  
Ischemic Muscle
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