scholarly journals Engineering Silk Fibroin‐Based Nerve Conduit with Neurotrophic Factors for Proximal Protection after Peripheral Nerve Injury

2020 ◽  
pp. 2000753
Author(s):  
Cristiana R. Carvalho ◽  
Wei Chang ◽  
Joana Silva‐Correia ◽  
Rui L. Reis ◽  
Joaquim M. Oliveira ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Nerve Injury ◽  
Silk Fibroin ◽  
Neurotrophic Factors ◽  
Peripheral Nerve Injury ◽  
Nerve Conduit ◽  
Proximal Protection

scholarly journals Past, Present, and Future of Nerve Conduits in the Treatment of Peripheral Nerve Injury

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Aikeremujiang Muheremu ◽  
Qiang Ao
Keyword(s):  
Stem Cells ◽  
Clinical Practice ◽  
Peripheral Nerve ◽  
Schwann Cells ◽  
Nerve Injury ◽  
Neurotrophic Factors ◽  
Peripheral Nerve Injury ◽  
Functional Outcomes ◽  
Nerve Conduits ◽  
New Construction

With significant advances in the research and application of nerve conduits, they have been used to repair peripheral nerve injury for several decades. Nerve conduits range from biological tubes to synthetic tubes, and from nondegradable tubes to biodegradable tubes. Researchers have explored hollow tubes, tubes filled with scaffolds containing neurotrophic factors, and those seeded with Schwann cells or stem cells. The therapeutic effect of nerve conduits is improving with increasing choice of conduit material, new construction of conduits, and the inclusion of neurotrophic factors and support cells in the conduits. Improvements in functional outcomes are expected when these are optimized for use in clinical practice.

scholarly journals Time‐restricted release of multiple neurotrophic factors promotes axonal regeneration and functional recovery after peripheral nerve injury

2019 ◽  
Vol 33 (7) ◽  
pp. 8600-8613 ◽  
Author(s):  
Liangliang Huang ◽  
Bing Xia ◽  
Xiaowei Shi ◽  
Jianbo Gao ◽  
Yujie Yang ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Nerve Injury ◽  
Functional Recovery ◽  
Neurotrophic Factors ◽  
Peripheral Nerve Injury ◽  
Axonal Regeneration

scholarly journals A novel bioactive nerve conduit for the repair of peripheral nerve injury

2016 ◽  
Vol 11 (1) ◽  
pp. 150 ◽  
Author(s):  
Yi-xia Yin ◽  
Bin-bin Li ◽  
Qiong-jiao Yan ◽  
Xin-yu Wang ◽  
Shi-pu Li
Keyword(s):  
Peripheral Nerve ◽  
Nerve Injury ◽  
Peripheral Nerve Injury ◽  
Nerve Conduit
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