Zn 2+ Doped Ultrasmall Prussian Blue Nanotheranostic Agent for Breast Cancer Photothermal Therapy under MR Imaging Guidance

2019 ◽  
Vol 9 (1) ◽  
pp. 1900948 ◽  
Author(s):  
Pingbo Shou ◽  
Zhangsen Yu ◽  
Yiting Wu ◽  
Qiang Feng ◽  
Bangyi Zhou ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mr Imaging ◽  
Prussian Blue ◽  
Photothermal Therapy ◽  
Imaging Guidance

Glypican-3 antibody functionalized Prussian blue nanoparticles for targeted MR imaging and photothermal therapy of hepatocellular carcinoma

2014 ◽  
Vol 2 (23) ◽  
pp. 3686-3696 ◽  
Author(s):  
Zhenglin Li ◽  
Yongyi Zeng ◽  
Da Zhang ◽  
Ming Wu ◽  
Lingjie Wu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Mr Imaging ◽  
Minimally Invasive ◽  
Prussian Blue ◽  
Photothermal Therapy ◽  
Minimally Invasive Technique ◽  
Invasive Technique ◽  
Prussian Blue Nanoparticles ◽  
Mri Guided

MRI-guided photothermal therapy is becoming a more widely accepted minimally invasive technique.

Prussian blue-modified ferritin nanoparticles for effective tumor chemo-photothermal combination therapy via enhancing reactive oxygen species production

2019 ◽  
Vol 33 (9) ◽  
pp. 1202-1213 ◽  
Author(s):  
Hao Li ◽  
Wei Zhang ◽  
Li Ding ◽  
Xing-Wang Li ◽  
Yang Wu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Reactive Oxygen Species ◽  
Prussian Blue ◽  
Photothermal Therapy ◽  
Reactive Oxygen Species Production ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Therapy Effect ◽  
Species Production

To realize the photothermal therapy ability of Prussian blue-modified ferritin nanoparticles (PB-Ft NPs) and its synergistic effect with chemotherapy, PB-Ft NPs were synthesized by a simple surface double decomposition reaction. Mean sizes of ferritin and PB-Ft NPs were 10.4 nm and 12.6 nm, respectively. The obtained PB-Ft NPs were verified to have both the photothermal conversion ability of Prussian blue and the morphology of ferritin. The in vitro and in vivo photothermal therapy results confirm PB-Ft NPs can successfully inhibit the growth of murine breast cancer cell line (4T1) without any obvious side effect. Moreover, taking use of the peroxidase-like activity of PB-Ft NPs, the photothermal therapy effect of PB-Ft NPs effectively improved the curative effect of gemcitabine (GEM) via enhancing reactive oxygen species production. The obtained PB-Ft NPs can be served as a useful and safe photothermal therapy agent in breast cancer. Moreover, PB-Ft NPs-assisted photothermal therapy can be applied as an adjunctive therapy with various established cancer treatments such as chemotherapy.

MR Imaging with Histopathological Correlation in Vertebral Metastases of Breast Cancer

1992 ◽  
Vol 33 (3) ◽  
pp. 213-220 ◽  
Author(s):  
M. Petren-Mallmin ◽  
B. Nordstrom ◽  
I. Andreasson ◽  
R. Nyman ◽  
H. Jonsson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mr Imaging ◽  
Vertebral Metastases ◽  
Histopathological Correlation
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