Long-Term Prevention of Bacterial Infection and Enhanced Osteoinductivity of a Hybrid Coating with Selective Silver Toxicity

2019 ◽  
Vol 8 (5) ◽  
pp. 1801465 ◽  
Author(s):  
Kai Xie ◽  
Ziao Zhou ◽  
Yu Guo ◽  
Lei Wang ◽  
Guoyuan Li ◽  
...  
Keyword(s):  
Bacterial Infection ◽  
Hybrid Coating ◽  
Silver Toxicity

scholarly journals Do Face Masks Increase the Rate of Staphylococcus Aureus Infection as Secondary Infection during Covid-19?

2021 ◽  
Vol 8 (2) ◽  
pp. 01-04
Author(s):  
Mahdi Bozorgnia
Keyword(s):  
Staphylococcus Aureus ◽  
Side Effects ◽  
Bacterial Infection ◽  
Secondary Infection ◽  
Viral Diseases ◽  
Protective Device ◽  
Risk Of Infection ◽  
Bacterial Diseases ◽  
Aureus Infection

Nowadays due to the coronavirus disease 2019 (COVID-19) and to save our lives, we have to use masks in a wider range. Since masks are now considered a protective device to prevent some bacterial or viral diseases, especially COVID-19, and the advice is that we should use them to save our lives and the lives of others. It is true that masks have many benefits, but maybe they are also harmful. It seems that is possible in long- term masking, itself cause side effects or even other diseases. Therefore, since masks are now more widely used, its advantages and even disadvantages are important to us. We think, maybe there are harms that may cause other bacterial diseases as secondary bacterial infection that may be confused with COVID-19 because they may have similar symptoms or may increase the severity of it. In this article, we review Staphylococcus Aureus that may be exacerbate or cause infectious diseases and increase the risk of infection. We may be able to prevent them with some recommendations.

C1 inhibitor mitigates peritoneal injury in zymosan-induced peritonitis

2021 ◽  
Author(s):  
Toshikazu Ozeki ◽  
Masashi Mizuno ◽  
Daiki Iguchi ◽  
Hiroshi Kojima ◽  
Hangsoo Kim ◽  
...  
Keyword(s):  
Bacterial Infection ◽  
Complement Activation ◽  
Intraperitoneal Injection ◽  
Fungal Infections ◽  
Inflammatory Cells ◽  
C1 Inhibitor ◽  
Fungal Peritonitis ◽  
Activation Products ◽  
Peritoneal Lining

Peritonitis, due to a fungal or bacterial infection, leads to injury of the peritoneal lining and thereby forms a hazard for the long-term success of PD, and remains a lethal complication in PD patients. This study investigated whether C1 inhibitor (C1-INH) could protect against the progression of peritoneal injuries with five daily administrations of zymosan after mechanical scraping of rat peritoneum to mimic fungal peritonitis. Severe peritoneal injuries were seen in this model, accompanied by fibrinogen/fibrin exudation and peritoneal deposition of complement activation products such as activated C3 and C5b-9. However, intraperitoneal injection of C1-INH decreased peritoneal depositions of activated C3 and C5b-9, ameliorated peritoneal thickening and reduced influx of inflammatory cells and prevented production of peritoneal fibrous layers with both one and two doses of C1-INH each day. Our results suggest that C1-INH might be useful to protect against peritoneal injuries after causes of peritonitis such as fungal infections. This clinically available agent may thus help extend the duration of PD.

scholarly journals IgM Production by Bone Marrow Plasmablasts Contributes to Long-Term Protection against Intracellular Bacterial Infection

2010 ◽  
Vol 186 (2) ◽  
pp. 1011-1021 ◽  
Author(s):  
Rachael Racine ◽  
Maura McLaughlin ◽  
Derek D. Jones ◽  
Susan T. Wittmer ◽  
Katherine C. MacNamara ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bacterial Infection

scholarly journals Long-Term Effects of Early-Life Antibiotic Exposure on Resistance to Subsequent Bacterial Infection

mBio ◽  
2019 ◽  
Vol 10 (6) ◽  
Author(s):  
Claire Roubaud-Baudron ◽  
Victoria E. Ruiz ◽  
Alexander M. Swan ◽  
Bruce A. Vallance ◽  
Ceren Ozkul ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Bacterial Infection ◽  
Early Life ◽  
Disease Susceptibility ◽  
Antibiotic Exposure ◽  
Citrobacter Rodentium ◽  
Long Term Effects ◽  
Gastrointestinal Microbiota ◽  
Content Type

ABSTRACT Early-life antibiotic exposure may provoke long-lasting microbiota perturbation. Since a healthy gut microbiota confers resistance to enteric pathogens, we hypothesized that early-life antibiotic exposure would worsen the effects of a bacterial infection encountered as an adult. To test this hypothesis, C57BL/6 mice received a 5-day course of tylosin (macrolide), amoxicillin (β-lactam), or neither (control) early in life and were challenged with Citrobacter rodentium up to 80 days thereafter. The early-life antibiotic course led to persistent alterations in the intestinal microbiota and even with pathogen challenge 80 days later worsened the subsequent colitis. Compared to exposure to amoxicillin, exposure to tylosin led to greater disease severity and microbiota perturbation. Transferring the antibiotic-perturbed microbiota to germfree animals led to worsened colitis, indicating that the perturbed microbiota was sufficient for the increased disease susceptibility. These experiments highlight the long-term effects of early-life antibiotic exposure on susceptibility to acquired pathogens. IMPORTANCE The gastrointestinal microbiota protects hosts from enteric infections; while antibiotics, by altering the microbiota, may diminish this protection. We show that after early-life exposure to antibiotics host susceptibility to enhanced Citrobacter rodentium-induced colitis is persistent and that this enhanced disease susceptibility is transferable by the antibiotic-altered microbiota. These results strongly suggest that early-life antibiotics have long-term consequences on the gut microbiota and enteropathogen infection susceptibility.

Enhanced osteogenic activity and antibacterial performance in vitro of polyetheretherketone by plasma-induced graft polymerization of acrylic acid and incorporation of zinc ions

2021 ◽  
Author(s):  
Yuxiang Zhang ◽  
Hongfeng Wu ◽  
Bo Yuan ◽  
Xiangdong Zhu ◽  
Kai Zhang ◽  
...  
Keyword(s):  
Surface Modification ◽  
Acrylic Acid ◽  
Bacterial Infection ◽  
Graft Polymerization ◽  
Zinc Ions ◽  
Long Term Stability ◽  
Osteogenic Activity ◽  
Antibacterial Performance

Polyetheretherketone (PEEK) has been widely used in the fields of orthopedics and trauma, but weak osteointegration and bacterial infection affect its long-term stability and repair effects. Surface modification is an...

Skin-permissible NIR-actuated hyperthermia by a photothermally responsive hydrogel membrane for the effective treatment of antibiotic-resistant bacterial infection

2022 ◽  
Author(s):  
Zhongpeng Yu ◽  
Jie Sun ◽  
Hongling Deng ◽  
Hong Kan ◽  
Chen Xu ◽  
...  
Keyword(s):  
Bacterial Infection ◽  
Effective Treatment ◽  
Near Infrared ◽  
Healthcare Systems ◽  
Alternative Strategy ◽  
Infrared Light ◽  
Resistant Bacteria ◽  
Antibiotic Resistant ◽  
Hydrogel Membrane

With the long-term widespread overuse of antibiotics, a large number of antibiotic-resistant bacteria have emerged and become a serious threat to healthcare systems. As an alternative strategy, near-infrared light (NIR)-actuated...

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