scholarly journals 3D Bioprinting for Organ Regeneration

2016 ◽  
Vol 6 (1) ◽  
pp. 1601118 ◽  
Author(s):  
Haitao Cui ◽  
Margaret Nowicki ◽  
John P. Fisher ◽  
Lijie Grace Zhang
Keyword(s):  
3D Bioprinting ◽  
Organ Regeneration

scholarly journals 3D Bio-Printing: an Introduction to a New Approach for Cancer Patients at the Interface of Art and Medicine

Leonardo ◽  
2017 ◽  
Vol 50 (2) ◽  
pp. 195-196
Author(s):  
Eugen Bogdan Petcu
Keyword(s):  
Cancer Patients ◽  
Social Consequences ◽  
Clinical Settings ◽  
3D Bioprinting ◽  
Multidisciplinary Therapy ◽  
Significant Development ◽  
New Approach ◽  
Organ Regeneration ◽  
Art And Medicine ◽  
Actual Field

Cancer patients require a complex multidisciplinary therapy. In this context the 3D additive biological manufacturing could represent a significant development with potential significant medical and social consequences. This article reviews the 3D bioprinting methods and clinical settings in which this new revolutionary method could be applied. Apart from the actual field of post-cancer therapy prosthetics and medical education, this method could be applied in the actual molecular cancer research and organ regeneration/fabrication. Considering all of these, it is possible that in the future, 3D biological printing could be used on a regular basis in clinical oncology.

scholarly journals Multinozzle Multichannel Temperature Deposition System for Construction of a Blood Vessel

2017 ◽  
Vol 23 (1) ◽  
pp. 64-69 ◽  
Author(s):  
Huanbao Liu ◽  
Huixing Zhou ◽  
Haiming Lan ◽  
Fu Liu ◽  
Xuhan Wang
Keyword(s):  
Tissue Engineering ◽  
Blood Vessel ◽  
3D Model ◽  
Model Structure ◽  
3D Bioprinting ◽  
Porous Structures ◽  
Bioactive Materials ◽  
Organ Regeneration ◽  
Hierarchical Porous ◽  
Temperature Deposition

3D bioprinting is an emerging technology that drives us to construct the complicated tissues and organs consisting of various materials and cells, which has been in widespread use in tissue engineering and organ regeneration. However, the protection and accurate distribution of cells are the most urgent problems to achieve tissue and organ reconstruction. In this article, a multinozzle multichannel temperature deposition and manufacturing (MTDM) system is proposed to fabricate a blood vessel with heterogeneous materials and gradient hierarchical porous structures, which enables not only the reconstruction of a blood vessel with an accurate 3D model structure but also the capacity to distribute bioactive materials such as growth factors, nutrient substance, and so on. In addition, a coaxial focusing nozzle is proposed and designed to extrude the biomaterial and encapsulation material, which can protect the cell from damage. In the MTDM system, the tubular structure of a blood vessel was successfully fabricated with the different biomaterials, which proved that the MTDM system has a potential application prospect in tissue engineering and organ regeneration.

scholarly journals FRESH METHOD: 3D BIOPRINTING AS A NEW APPROACH FOR TISSUE AND ORGAN REGENERATION

2021 ◽  
Vol 7 (3) ◽  
pp. 79-82
Author(s):  
Alena Findrik Balogová ◽  
Marianna Trebuňová ◽  
Viktória Rajťúková ◽  
Radovan Hudák
Keyword(s):  
Additive Manufacturing ◽  
Three Dimensions ◽  
Live Cells ◽  
3D Bioprinting ◽  
New Approach ◽  
Cellular Spheroids ◽  
Organ Regeneration ◽  
Bearing Materials ◽  
Magnetic Resonance Imaging Mri ◽  
Viable Approach

Over the last decade, techniques of additive manufacturing of biomaterials have undergone a transformation, from a fast prototype tool used in research and development, to a viable approach in the production of customised medical devices. The key to this transformation is the ability of additive manufacturing to precisely define the structure and properties of a material in three dimensions, and to adjust those properties to unique anatomical and physiological criteria based on the medical data obtained by Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). The 3D bioprinting technique was developed as a solution to provide temporary and ubiquitous support of structures during the printing process. In general, integrated 3D printing may be understood as a building chamber that is filled with bearing materials, where biomaterials, cellular spheroids, cell-laden hydrogels and other materials (bioinks) are deposited using a syringe-based extruder. In particular, FRESH 3D bioprinting is a revolutionary technology, which may bring a fast and efficient advancement to medicine thanks to the ability to print new tissues from live cells.

Organ regeneration: integration application of cell encapsulation and 3D bioprinting

2017 ◽  
Vol 12 (4) ◽  
pp. 279-289 ◽  
Author(s):  
Huanbao Liu ◽  
Huixing Zhou ◽  
Haiming Lan ◽  
Tianyu Liu
Keyword(s):  
Cell Encapsulation ◽  
3D Bioprinting ◽  
Organ Regeneration

scholarly journals 3D Printing of Polysaccharide-Based Self-Healing Hydrogel Reinforced with Alginate for Secondary Cross-Linking

Biomedicines ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 1224
Author(s):  
Hyun-Ho Roh ◽  
Hyun-Seung Kim ◽  
Chunggoo Kim ◽  
Kuen-Yong Lee
Keyword(s):  
Three Dimensional ◽  
Cartilage Regeneration ◽  
Cross Linking ◽  
Self Healing ◽  
3D Bioprinting ◽  
Glycol Chitosan ◽  
Organ Regeneration ◽  
Custom Made ◽  
Potential Applications

Three-dimensional (3D) bioprinting has been attractive for tissue and organ regeneration with the possibility of constructing biologically functional structures useful in many biomedical applications. Autonomous healing of hydrogels composed of oxidized hyaluronate (OHA), glycol chitosan (GC), and adipic acid dihydrazide (ADH) was achieved after damage. Interestingly, the addition of alginate (ALG) to the OHA/GC/ADH self-healing hydrogels was useful for the dual cross-linking system, which enhanced the structural stability of the gels without the loss of their self-healing capability. Various characteristics of OHA/GC/ADH/ALG hydrogels, including viscoelastic properties, cytotoxicity, and 3D printability, were investigated. Additionally, potential applications of 3D bioprinting of OHA/GC/ADH/ALG hydrogels for cartilage regeneration were investigated in vitro. This hydrogel system may have potential for bioprinting of a custom-made scaffold in various tissue engineering applications.

scholarly journals 3D Bioprinting Strategies for the Regeneration of Functional Tubular Tissues and Organs

2020 ◽  
Vol 7 (2) ◽  
pp. 32 ◽  
Author(s):  
Hun-Jin Jeong ◽  
Hyoryung Nam ◽  
Jinah Jang ◽  
Seung-Jae Lee
Keyword(s):  
Cell Sheet ◽  
Biological Properties ◽  
Free Form ◽  
3D Bioprinting ◽  
Cell Sheet Engineering ◽  
Tissue Constructs ◽  
Functional Tissue ◽  
Organ Regeneration ◽  
Mold Casting ◽  
Multiple Processes

It is difficult to fabricate tubular-shaped tissues and organs (e.g., trachea, blood vessel, and esophagus tissue) with traditional biofabrication techniques (e.g., electrospinning, cell-sheet engineering, and mold-casting) because these have complicated multiple processes. In addition, the tubular-shaped tissues and organs have their own design with target-specific mechanical and biological properties. Therefore, the customized geometrical and physiological environment is required as one of the most critical factors for functional tissue regeneration. 3D bioprinting technology has been receiving attention for the fabrication of patient-tailored and complex-shaped free-form architecture with high reproducibility and versatility. Printable biocomposite inks that can facilitate to build tissue constructs with polymeric frameworks and biochemical microenvironmental cues are also being actively developed for the reconstruction of functional tissue. In this review, we delineated the state-of-the-art of 3D bioprinting techniques specifically for tubular tissue and organ regeneration. In addition, this review described biocomposite inks, such as natural and synthetic polymers. Several described engineering approaches using 3D bioprinting techniques and biocomposite inks may offer beneficial characteristics for the physiological mimicry of human tubular tissues and organs.

scholarly journals Current Developments in 3D Bioprinting for Tissue and Organ Regeneration–A Review

2020 ◽  
Vol 6 ◽  
Author(s):  
Swarnima Agarwal ◽  
Shreya Saha ◽  
Vamsi Krishna Balla ◽  
Aniruddha Pal ◽  
Ananya Barui ◽  
...  
Keyword(s):  
3D Bioprinting ◽  
Organ Regeneration

Resolution of 3D bioprinting inside bulk gel and granular gel baths

Soft Matter ◽  
2021 ◽  
Author(s):  
Zheng-Tian Xie ◽  
Dong-Hee Kang ◽  
Michiya Matsusaki
Keyword(s):  
Tissue Engineering ◽  
Three Dimensional ◽  
Cutting Edge ◽  
3D Bioprinting ◽  
Organ Regeneration

Three-dimensional (3D) bioprinting has rapidly developed in the last decade, playing an increasingly important role in applications including pharmacokinetics research, tissue engineering, and organ regeneration. As a cutting-edge technology in...

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