scholarly journals Tissue Engineering: Anisotropic Cellular Network Formation in Engineered Muscle Tissue through the Self-Organization of Neurons and Endothelial Cells (Adv. Healthcare Mater. 3/2015)

2015 ◽  
Vol 4 (3) ◽  
pp. 478-478
Author(s):  
Hironobu Takahashi ◽  
Tatsuya Shimizu ◽  
Masamichi Nakayama ◽  
Masayuki Yamato ◽  
Teruo Okano
2014 ◽  
Vol 4 (3) ◽  
pp. 356-360 ◽  
Author(s):  
Hironobu Takahashi ◽  
Tatsuya Shimizu ◽  
Masamichi Nakayama ◽  
Masayuki Yamato ◽  
Teruo Okano

Biomaterials ◽  
2013 ◽  
Vol 34 (30) ◽  
pp. 7372-7380 ◽  
Author(s):  
Hironobu Takahashi ◽  
Tatsuya Shimizu ◽  
Masamichi Nakayama ◽  
Masayuki Yamato ◽  
Teruo Okano

2013 ◽  
Vol 15 (1) ◽  
pp. 115-136 ◽  
Author(s):  
Kyriacos A. Athanasiou ◽  
Rajalakshmanan Eswaramoorthy ◽  
Pasha Hadidi ◽  
Jerry C. Hu

2017 ◽  
Vol 68 (6) ◽  
pp. 1341-1344
Author(s):  
Grigore Berea ◽  
Gheorghe Gh. Balan ◽  
Vasile Sandru ◽  
Paul Dan Sirbu

Complex interactions between stem cells, vascular cells and fibroblasts represent the substrate of building microenvironment-embedded 3D structures that can be grafted or added to bone substitute scaffolds in tissue engineering or clinical bone repair. Human Adipose-derived Stem Cells (hASCs), human umbilical vein endothelial cells (HUVECs) and normal dermal human fibroblasts (NDHF) can be mixed together in three dimensional scaffold free constructs and their behaviour will emphasize their potential use as seeding points in bone tissue engineering. Various combinations of the aforementioned cell lines were compared to single cell line culture in terms of size, viability and cell proliferation. At 5 weeks, viability dropped for single cell line spheroids while addition of NDHF to hASC maintained the viability at the same level at 5 weeks Fibroblasts addition to the 3D construct of stem cells and endothelial cells improves viability and reduces proliferation as a marker of cell differentiation toward osteogenic line.


2006 ◽  
Vol 1 (3) ◽  
pp. 333-343 ◽  
Author(s):  
Masashi Nomi ◽  
Hideaki Miyake ◽  
Yoshifumi Sugita ◽  
Masato Fujisawa ◽  
Shay Soker

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