Controlled Cell Growth and Cell Migration in Periodic Mesoporous Organosilica/Alginate Nanocomposite Hydrogels

2015 ◽  
Vol 5 (2) ◽  
pp. 193-197 ◽  
Author(s):  
Nermin Seda Kehr ◽  
Kristina Riehemann
Keyword(s):  
Cell Migration ◽  
Cell Growth ◽  
Periodic Mesoporous Organosilica ◽  
Nanocomposite Hydrogels ◽  
Mesoporous Organosilica

Periodic Mesoporous Organosilica-Based Nanocomposite Hydrogels as Three-Dimensional Scaffolds

2012 ◽  
Vol 52 (4) ◽  
pp. 1156-1160 ◽  
Author(s):  
Nermin Seda Kehr ◽  
Eko Adi Prasetyanto ◽  
Kathrin Benson ◽  
Bahar Ergün ◽  
Anzhela Galstyan ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Periodic Mesoporous Organosilica ◽  
Nanocomposite Hydrogels ◽  
Mesoporous Organosilica

Periodic Mesoporous Organosilica-Based Nanocomposite Hydrogels as Three-Dimensional Scaffolds

2012 ◽  
Vol 125 (4) ◽  
pp. 1194-1198 ◽  
Author(s):  
Nermin Seda Kehr ◽  
Eko Adi Prasetyanto ◽  
Kathrin Benson ◽  
Bahar Ergün ◽  
Anzhela Galstyan ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Periodic Mesoporous Organosilica ◽  
Nanocomposite Hydrogels ◽  
Mesoporous Organosilica

Light-harvesting photocatalysis for H2 evolution by methylacridone-bridged periodic mesoporous organosilica

2021 ◽  
Vol 287 ◽  
pp. 119965
Author(s):  
Yasutomo Goto ◽  
Ken-ichi Yamanaka ◽  
Masataka Ohashi ◽  
Yoshifumi Maegawa ◽  
Shinji Inagaki
Keyword(s):  
Light Harvesting ◽  
H2 Evolution ◽  
Periodic Mesoporous Organosilica ◽  
Mesoporous Organosilica

scholarly journals MiR-188-3p and miR-133b Suppress Cell Proliferation in Human Hepatocellular Carcinoma via Post-Transcriptional Suppression of NDRG1

2021 ◽  
Vol 20 ◽  
pp. 153303382110330
Author(s):  
Zhenzhao Luo ◽  
Yue Fan ◽  
Xianchang Liu ◽  
Shuiyi Liu ◽  
Xiaoyu Kong ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Proliferation ◽  
Cell Migration ◽  
Cell Growth ◽  
Suppressive Effect ◽  
Luciferase Reporter ◽  
Invasion And Migration ◽  
And Migration ◽  
Cancer Tissues ◽  
Suppress Cell Proliferation

Background: Previous studies reported that N-myc downstream-regulated gene 1 (NDRG1) was upregulated in various cancer tissues and decreased expression of miR-188-3p and miR-133b could suppress cell proliferation, metastasis, and invasion and induce apoptosis of cancer cells. However, the molecular mechanism of NRDG1 involved in hepatocellular carcinoma (HCC) tumorigenesis is still unknown. Methods: The expressions of miR-188-3p, miR-133b, and NRDG1 in HCC tissues and cells were quantified by qRT-PCR and Western blot. MTT assay and transwell invasion assay were performed to evaluate cell growth and cell migration, respectively. Luciferase reporter assay were performed to determine whether miR-188-3p and miR-133b could directly bind to NRDG1 in HCC cells. Results: The results showed that NRDG1 was upregulated and these 2 microRNAs were downregulated in HCC tissues. NRDG1 was negatively correlated with miR-188-3p and miR-133b in HCC tissues. MiR-188-3p and miR-133b were demonstrated to directly bind to 3′UTR of NRDG1 and inhibit its expression. Upregulation of miR-188-3p and miR-133b reduced NRDG1 expression in hepatocellular carcinoma cell lines, which consequently inhibited cell growth and cell migration. Conclusions: Our finding suggested that miR-188-3p and miR-133b exert a suppressive effect on hepatocellular carcinoma proliferation, invasion, and migration through downregulation of NDRG1.

Controlled PEGylation of periodic mesoporous organosilica nanospheres for improving their stability in physiological solutions

2019 ◽  
Vol 30 (4) ◽  
pp. 929-932 ◽  
Author(s):  
Xiaodan Su ◽  
Jun Tao ◽  
Qing Wang ◽  
Peng Xu ◽  
Wei Luo ◽  
...  
Keyword(s):  
Periodic Mesoporous Organosilica ◽  
Mesoporous Organosilica

Chemical sensors based on nano-sized lanthanide-grafted periodic mesoporous organosilica hybrid materials

2019 ◽  
Vol 7 (26) ◽  
pp. 8109-8119 ◽  
Author(s):  
Anna M. Kaczmarek ◽  
Pascal Van Der Voort
Keyword(s):  
Hybrid Materials ◽  
Chemical Sensors ◽  
Aprotic Solvent ◽  
Periodic Mesoporous Organosilica ◽  
Ion Sensing ◽  
Mesoporous Organosilica

Nano-sized PMOs grafted with lanthanides show selective ion sensing for Pb2+ and Cr3+ and strong solvatochromism allowing their use as protic and aprotic solvent sensors.

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