Hybrid BaYbF5Nanoparticles: Novel Binary Contrast Agent for High-Resolution in Vivo X-ray Computed Tomography Angiography

2012 ◽  
Vol 1 (4) ◽  
pp. 461-466 ◽  
Author(s):  
Yanlan Liu ◽  
Kelong Ai ◽  
Jianhua Liu ◽  
Qinghai Yuan ◽  
Yangyang He ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Contrast Agent ◽  
Computed Tomography Angiography ◽  
X Ray ◽  
X Ray Computed

A High-Performance Ytterbium-Based Nanoparticulate Contrast Agent for In Vivo X-Ray Computed Tomography Imaging

2011 ◽  
Vol 124 (6) ◽  
pp. 1466-1471 ◽  
Author(s):  
Yanlan Liu ◽  
Kelong Ai ◽  
Jianhua Liu ◽  
Qinghai Yuan ◽  
Yangyang He ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Contrast Agent ◽  
High Performance ◽  
Computed Tomography Imaging ◽  
X Ray ◽  
Tomography Imaging ◽  
X Ray Computed

Large-Scale Synthesis of Bi2S3Nanodots as a Contrast Agent for In Vivo X-ray Computed Tomography Imaging

2011 ◽  
Vol 23 (42) ◽  
pp. 4886-4891 ◽  
Author(s):  
Kelong Ai ◽  
Yanlan Liu ◽  
Jianhua Liu ◽  
Qinghai Yuan ◽  
Yangyang He ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Contrast Agent ◽  
Large Scale ◽  
Computed Tomography Imaging ◽  
X Ray ◽  
Tomography Imaging ◽  
X Ray Computed ◽  
Large Scale Synthesis

Antibiofouling Polymer-Coated Gold Nanoparticles as a Contrast Agent for in Vivo X-ray Computed Tomography Imaging

2007 ◽  
Vol 129 (24) ◽  
pp. 7661-7665 ◽  
Author(s):  
Dongkyu Kim ◽  
Sangjin Park ◽  
Jae Hyuk Lee ◽  
Yong Yeon Jeong ◽  
Sangyong Jon
Keyword(s):  
Computed Tomography ◽  
Gold Nanoparticles ◽  
Contrast Agent ◽  
Computed Tomography Imaging ◽  
X Ray ◽  
Tomography Imaging ◽  
X Ray Computed

A High-Performance Ytterbium-Based Nanoparticulate Contrast Agent for In Vivo X-Ray Computed Tomography Imaging

2011 ◽  
Vol 51 (6) ◽  
pp. 1437-1442 ◽  
Author(s):  
Yanlan Liu ◽  
Kelong Ai ◽  
Jianhua Liu ◽  
Qinghai Yuan ◽  
Yangyang He ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Contrast Agent ◽  
High Performance ◽  
Computed Tomography Imaging ◽  
X Ray ◽  
Tomography Imaging ◽  
X Ray Computed

Contrast enhancement of iohexol-cisplatin-gelatin complex under computed tomography imaging

2014 ◽  
Vol 34 (3) ◽  
pp. 267-271
Author(s):  
Wei-Hung Liu ◽  
Yang-Kao Wang ◽  
Chi-Chang Wu ◽  
Win-Pin Deng ◽  
Kuang-Hsun Lin ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Contrast Agent ◽  
Diagnostic Techniques ◽  
The Body ◽  
X Ray ◽  
Non Invasive ◽  
Ct Contrast Agent ◽  
X Ray Computed ◽  
Ct Contrast

Abstract X-ray computed tomography (CT) is one of the most powerful non-invasive diagnostic techniques nowadays. The iodinated molecules used as CT contrast agents in the clinic have short circulation times in the body, which significantly restrict its applications. Furthermore, some patients are hypersensitive to iodine. So, researchers have made tremendous efforts to improve the property of iodine. Besides, cis-diammineplatinum (II) dichloride (cisplatin), a major chemo agent for cancer treatment, possess higher X-ray attenuation coefficient being a CT contrast agent. The incorporation of cisplatin with an iodinated agent could facilitate the quality of CT images and damage cancer cells simultaneously. To reduce toxicity of a contrast agent, polymer matrix, gelatin, was incorporated for avoiding contact with nontarget cells. In this study, we combined the iodine contrast agent, 1,3-N-bis (2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodobenzene-1,3-dicarboxamide (iohexol), with cisplatin, and then examined them in a micro CT with different X-ray tube voltages (50 kV, 80 kV, 100 kV) to find optimal scanning conditions for imaging. As expected, iohexol combined with cisplatin enhanced X-ray attenuation and image contrast. The optimal CT image could be acquired at iohexol and cisplatin concentrations of 50 mg/ml and 3 mg/ml, respectively, under 80 kV irradiation. Finally, the iohexol-cisplatin-gelatin solution was then fabricated into nanoparticles of sizes about 240 nm, which may suitable for in vivo delivery.

scholarly journals A Bismuth Metal–Organic Framework as a Contrast Agent for X-ray Computed Tomography

2019 ◽  
Vol 2 (3) ◽  
pp. 1197-1203 ◽  
Author(s):  
Lee Robison ◽  
Lin Zhang ◽  
Riki J. Drout ◽  
Peng Li ◽  
Chad R. Haney ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Contrast Agent ◽  
Metal Organic Framework ◽  
X Ray ◽  
Metal Organic ◽  
X Ray Computed ◽  
Organic Framework
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