Bifunctional Cx43 Mimic Peptide Grafted Hyaluronic Acid Hydrogels Inhibited Tumor Recurrence and Stimulated Wound Healing for Postsurgical Tumor Treatment

2020 ◽  
Vol 30 (51) ◽  
pp. 2004709
Author(s):  
Dan He ◽  
Haiyan Li
Keyword(s):  
Wound Healing ◽  
Hyaluronic Acid ◽  
Tumor Recurrence ◽  
Tumor Treatment ◽  
Mimic Peptide

Dressings and topical agents containing hyaluronic acid for wound healing

2010 ◽  
Author(s):  
Neil A Smart ◽  
Howard Talbot ◽  
Jim Frangos ◽  
Tawfique Chowdhury ◽  
Hazim Faragallah
Keyword(s):  
Wound Healing ◽  
Hyaluronic Acid

scholarly journals Polylactic acid-based electrospun fiber and hyaluronic acid-valsartan hydrogel scaffold for chronic wound healing

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Margaret O. Ilomuanya ◽  
Prosper S. Okafor ◽  
Joyce N. Amajuoyi ◽  
John C. Onyejekwe ◽  
Omotunde O. Okubanjo ◽  
...  
Keyword(s):  
Wound Healing ◽  
Hyaluronic Acid ◽  
Polylactic Acid ◽  
Chronic Wound ◽  
Electrospun Fiber ◽  
Hydrogel Scaffold

scholarly journals Wound Healing Promotion by Hyaluronic Acid: Effect of Molecular Weight on Gene Expression and In Vivo Wound Closure

2021 ◽  
Vol 14 (4) ◽  
pp. 301
Author(s):  
Yayoi Kawano ◽  
Viorica Patrulea ◽  
Emmanuelle Sublet ◽  
Gerrit Borchard ◽  
Takuya Iyoda ◽  
...  
Keyword(s):  
Gene Expression ◽  
Molecular Weight ◽  
Wound Healing ◽  
Hyaluronic Acid ◽  
Healing Process ◽  
Dermal Fibroblasts ◽  
Water Soluble ◽  
Wound Healing Process ◽  
And Migration ◽  
Proliferation And Migration

Hyaluronic acid (HA) has been known to play an important role in wound healing process. However, the effect of molecular weight (MW) of exogenously administered HA on the wound healing process has not been fully understood. In this study, we investigated HA with different MWs on wound healing process using human epidermal keratinocytes and dermal fibroblasts. Cell proliferation and migration ability were assessed by water soluble tetrazolium (WST) assay and wound scratch assay. We examined the effect of HA addition in a full-thickness wound model in mice and the gene expression related to wound healing. Proliferation and migration of HaCaT cells increased with the increase of MW and concentration of HA. Interleukin (IL-1β), IL-8 and vascular endothelial growth factor (VEGF) as well as matrix metalloproteinase (MMP)-9 and MMP-13 were significantly upregulated by high molecular weight (HMW) HA in keratinocytes. Together with VEGF upregulation and the observed promotion of HaCaT migration, HA with the MW of 2290 kDa may hold potential to improve re-epithelialization, a critical obstacle to heal chronic wounds.

Carboxymethyl chitosan/gelatin/hyaluronic acid blended-membranes as epithelia transplanting scaffold for corneal wound healing

2018 ◽  
Vol 192 ◽  
pp. 240-250 ◽  
Author(s):  
Wenhua Xu ◽  
Zheying Wang ◽  
Ying Liu ◽  
Liping Wang ◽  
Zhiwen Jiang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Hyaluronic Acid ◽  
Carboxymethyl Chitosan ◽  
Corneal Wound Healing ◽  
Corneal Wound

Evaluation of characteristics and in vitro antioxidant properties of RSV loaded hyaluronic acid–DPPC microparticles as a wound healing system

2015 ◽  
Vol 126 ◽  
pp. 50-57 ◽  
Author(s):  
İpek Eroğlu ◽  
Evren H. Gökçe ◽  
Nicolas Tsapis ◽  
Sakine Tuncay Tanrıverdi ◽  
Göksel Gökçe ◽  
...  
Keyword(s):  
Wound Healing ◽  
Hyaluronic Acid ◽  
Antioxidant Properties ◽  
Healing System

scholarly journals Studies in Fetal Wound Healing V. A Prolonged Presence of Hyaluronic Acid Characterizes Fetal Wound Fluid

1991 ◽  
Vol 213 (4) ◽  
pp. 292-296 ◽  
Author(s):  
MICHAEL T. LONGAKER ◽  
ERNIE S. CHIU ◽  
N. SCOTT ADZICK ◽  
MICHAEL STERN ◽  
MICHAEL R. HARRISON ◽  
...  
Keyword(s):  
Wound Healing ◽  
Hyaluronic Acid ◽  
Wound Fluid ◽  
Fetal Wound Healing ◽  
Fetal Wound

scholarly journals Preparation of Foam Dressings Based on Gelatin, Hyaluronic Acid, and Carboxymethyl Chitosan Containing Fibroblast Growth Factor-7 for Dermal Regeneration

Polymers ◽  
2021 ◽  
Vol 13 (19) ◽  
pp. 3279
Author(s):  
Longhao Jin ◽  
Sun-Jung Yoon ◽  
Dae Hoon Lee ◽  
Yun Chang Pyun ◽  
Woo Youp Kim ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Wound Healing ◽  
Hyaluronic Acid ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Wound Dressing ◽  
Transmission Rate ◽  
Carboxymethyl Chitosan ◽  
Amide Bond ◽  
Fibroblast Growth

Wound recovery close to the function of the native skin is the goal of wound healing. In this study, we prepared foam dressings (FDs; 2-GHC-FD-1–9, 5-GHC-FD-1–9, and 10-GHC-FD-1–9) composed of various concentrations of gelatin, hyaluronic acid, and carboxymethyl chitosan, which are chemically interconnected through amide bond formation, for evaluating wound healing. Tensile and cell proliferation tests showed that 2-GHC-FD-1–9 are suitable for wound dressing. For further evaluation, three types of FDs, 2-GHC-FD-1, 2-GHC-FD-4, and 2-GHC-FD-8 were chosen. The results of animal intradermal reactivity, water vapor transmission rate, and absorption rate of the three FDs indicated that 2-GHC-FD-8 is the most appropriate scaffold for wound healing. For wound healing acceleration, various concentrations of fibroblast growth factor-7 (FGF-7) was soaked in 2-GHC-FD-8 (2-GHC-FD-8/F1-6) and evaluated by using scanning electron microscopy, cell proliferation, release behavior, and in vivo animal tests. The FDs showed interconnected porous structures, increased cell proliferation until 8.0 × 10−11 M, controlled release with initial burst within 1 h, and sustained release for 48 h. The results of the animal test showed an appropriate concentration of FGF-7 for wound healing. In addition, 2-GHC-FD-8 is a suitable scaffold for wound healing. Therefore, we suggest that 2-GHC-FD-8/F3 is a useful wound dressing for accelerating wound healing.

scholarly journals Role of hyaluronic acid based hydrogel in management of wound healing effect

2019 ◽  
Vol 4 (6) ◽  
pp. 152-160
Author(s):  
Kiran Baviskar ◽  
Tanvir Shaikh ◽  
Kiran D. Patil ◽  
Rahul Baviskar ◽  
Santram Lodhi
Keyword(s):  
Wound Healing ◽  
Hyaluronic Acid ◽  
Healing Effect ◽  
Wound Healing Effect
Sign in / Sign up

Export Citation Format

Share Document