Stimuli‐Responsive Scaffold for Breast Cancer Treatment Combining Accurate Photothermal Therapy and Adipose Tissue Regeneration

2019 ◽  
Vol 29 (36) ◽  
pp. 1904401 ◽  
Author(s):  
Guo Bai ◽  
Pingyun Yuan ◽  
Bolei Cai ◽  
Xinyu Qiu ◽  
Ronghua Jin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Adipose Tissue ◽  
Cancer Treatment ◽  
Tissue Regeneration ◽  
Photothermal Therapy ◽  
Breast Cancer Treatment ◽  
Stimuli Responsive

Implications for breast cancer treatment from increased autotaxin production in adipose tissue after radiotherapy

2017 ◽  
Vol 31 (9) ◽  
pp. 4064-4077 ◽  
Author(s):  
Guanmin Meng ◽  
Xiaoyun Tang ◽  
Zelei Yang ◽  
Matthew G. K. Benesch ◽  
Alison Marshall ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Adipose Tissue ◽  
Cancer Treatment ◽  
Breast Cancer Treatment

Ultra-sound Shear Wave Elastography Tissue Stiffness and Thickness Assessment After Adjuvant Radiotherapy for Breast Cancer Treatment; An Exploratory Study.

2021 ◽  
Author(s):  
Catherine Hunt ◽  
Anita Bourke ◽  
Joshua Dass ◽  
Tammy Corica ◽  
Sueli Hardwick ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Adipose Tissue ◽  
Cancer Treatment ◽  
Shear Wave ◽  
Subcutaneous Adipose Tissue ◽  
Shear Wave Elastography ◽  
Breast Cancer Treatment ◽  
Tissue Thickness ◽  
Pectoral Region ◽  
Subcutaneous Adipose

Abstract Purpose: This research investigated the feasibility of using B-mode ultrasound with shear-wave elastography (SWE) to evaluate the structural and mechanical properties of multiple tissue layers in the pectoral region of women with chronic radiation fibrosis following breast cancer treatment. Method: Nine women between one and five years post unilateral conventional fractionated radiotherapy were evaluated. Both ultrasound and SWE were used to examine the thickness and stiffness of skin, subcutaneous adipose tissue, fascia and muscle in both their irradiated and non-irradiated sides. Linear mixed models were conducted to examine statistical differences in tissue thickness and stiffness between irradiated and non-irradiated sides with the arm resting by the side and also in abduction. Results: Significant differences were found between irradiated and non-irradiated tissues. Irradiated skin was significantly thicker (p=0.020) and stiffer (p<0.001) with the arm by the side. Irradiated subcutaneous adipose tissue was significantly thinner (p<0.001). Irradiated fascia and muscles thinned significantly with the arm moved out to abduction position. Irradiated pectoral muscle was significantly stiffer (p=0.004), this stiffness amplified with arm abduction (p<0.001) where the muscle thinned significantly (P<0.001).Conclusion: Ultrasound with SWE shows potential to provide novel objective evaluation of radiation induced soft tissue fibrosis at multiple tissue layers in the pectoral region. Tissue thickness changes in irradiated tissue were evident in ultrasound images. Quantifying these tissue changes supports research development and introduction of clinical interventions to ameliorate the symptoms of morbidity that is currently considered irreversible.

Two-photon excitation triggers combined chemo-photothermal therapy via doped carbon nanohybrid dots for effective breast cancer treatment

2017 ◽  
Vol 330 ◽  
pp. 651-662 ◽  
Author(s):  
Sara Madadi Ardekani ◽  
Alireza Dehghani ◽  
Mahbub Hassan ◽  
Mehran Kianinia ◽  
Igor Aharonovich ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Treatment ◽  
Photothermal Therapy ◽  
Breast Cancer Treatment ◽  
Two Photon ◽  
Photon Excitation ◽  
Two Photon Excitation
Sign in / Sign up

Export Citation Format

Share Document