Tunable Förster Resonance Energy Transfer in Colloidal Nanoparticles Composed of Polycaprolactone-Tethered Donors and Acceptors: Enhanced Near-Infrared Emission and Compatibility for In Vitro and In Vivo Bioimaging

2017 ◽  
Vol 28 (7) ◽  
pp. 1705226 ◽  
Author(s):  
Cangjie Yang ◽  
Xiaochen Wang ◽  
Shuo Huang ◽  
Mingfeng Wang
Keyword(s):  
Energy Transfer ◽  
Near Infrared ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Infrared Emission ◽  
Förster Resonance Energy Transfer ◽  
Colloidal Nanoparticles ◽  
Near Infrared Emission

Tunable near-infrared emission of binary nano- and mesoscale GUMBOS

RSC Advances ◽  
2014 ◽  
Vol 4 (54) ◽  
pp. 28471-28480 ◽  
Author(s):  
Atiya N. Jordan ◽  
Noureen Siraj ◽  
Susmita Das ◽  
Isiah M. Warner
Keyword(s):  
Energy Transfer ◽  
Near Infrared ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Emission Spectra ◽  
Infrared Emission ◽  
Förster Resonance Energy Transfer ◽  
Near Infrared Emission ◽  
Tunable Emission ◽  
Förster Resonance

Mixtures of GUMBOS were used to form binary nanomaterials with tunable emission spectra due to Förster resonance energy transfer (FRET).

scholarly journals Förster Resonance Energy Transfer-Based Stability Assessment of PLGA Nanoparticles in Vitro and in Vivo

2019 ◽  
Vol 2 (3) ◽  
pp. 1131-1140 ◽  
Author(s):  
Edyta Swider ◽  
Sanish Maharjan ◽  
Karlijne Houkes ◽  
Nicolaas Koen van Riessen ◽  
Carl Figdor ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Plga Nanoparticles ◽  
Forster Resonance Energy Transfer ◽  
Förster Resonance Energy Transfer ◽  
Stability Assessment ◽  
Förster Resonance

Fluorescence resonance energy transfer (FRET) based nanoparticles composed of AIE luminogens and NIR dyes with enhanced three-photon near-infrared emission for in vivo brain angiography

Nanoscale ◽  
2018 ◽  
Vol 10 (21) ◽  
pp. 10025-10032 ◽  
Author(s):  
Wen Liu ◽  
Yalun Wang ◽  
Xiao Han ◽  
Ping Lu ◽  
Liang Zhu ◽  
...  
Keyword(s):  
Near Infrared ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Infrared Emission ◽  
Biological Imaging ◽  
High Contrast ◽  
Nir Dyes ◽  
Nir Fluorescence ◽  
Near Infrared Emission

Near-infrared (NIR) fluorescence is very important for high-contrast biological imaging of high-scattering tissues such as brain tissue.

A diphenylacrylonitrile conjugated porphyrin with near-infrared emission by AIE–FRET

2019 ◽  
Vol 43 (8) ◽  
pp. 3317-3322 ◽  
Author(s):  
Chenyang Han ◽  
Shengjie Jiang ◽  
Jiabin Qiu ◽  
Hongyu Guo ◽  
Fafu Yang
Keyword(s):  
Energy Transfer ◽  
Fluorescence Resonance Energy Transfer ◽  
Near Infrared ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Infrared Emission ◽  
Aggregation Induced Emission ◽  
Fluorescence Resonance ◽  
Near Infrared Emission

The strong aggregation induced emission–fluorescence resonance energy transfer (AIE–FRET) effect was observed for diphenylacrylonitrile units and porphyrin units.

scholarly journals Affinity series of genetically encoded high sensitivity Förster Resonance Energy Transfer sensors for sucrose

2020 ◽  
Author(s):  
Mayuri Sadoine ◽  
Mira Reger ◽  
Ka Man Wong ◽  
Wolf B. Frommer
Keyword(s):  
Energy Transfer ◽  
Steady State ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Forster Resonance Energy Transfer ◽  
Förster Resonance Energy Transfer ◽  
Detection Range ◽  
Steady State Levels ◽  
Förster Resonance

ABSTRACTGenetically encoded fluorescent sugar sensors are valuable tools for the discovery of transporters and for quantitative monitoring of sugar steady-state levels in intact tissues. Genetically encoded Förster Resonance Energy Transfer sensors for glucose have been designed and optimized extensively, and a full series of affinity mutants is available for in vivo studies. However, to date, only a single improved sensor FLIPsuc-90µΔ1 with a Km for sucrose of ∼90 µM is available for sucrose monitoring. This sucrose sensor was engineered on the basis of an Agrobacterium tumefaciens sugar binding protein. Here, we took a two-step approach to first systematically improve the dynamic range of the FLIPsuc nanosensor and then expand the detection range from micromolar to millimolar sucrose concentrations by mutating a key residue in the binding site. The resulting series of sucrose sensors may allow systematic investigation of sucrose transporter candidates and comprehensive in vivo analyses of sucrose concentration in plants. Since FLIPsuc-90µ also detects trehalose in animal cells, the new series of sensors can be used to investigate trehalose transporter candidates and monitor trehalose steady-state levels in vivo as well.

Organic nanoparticle tracking during pharmacokinetic studies

Nanomedicine ◽  
2021 ◽  
Author(s):  
Samuel Bonnet ◽  
Rana Elfatairi ◽  
Florence Franconi ◽  
Emilie Roger ◽  
Samuel Legeay
Keyword(s):  
Energy Transfer ◽  
Structural Integrity ◽  
Biological Fluids ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Förster Resonance Energy Transfer ◽  
Pharmacokinetic Studies ◽  
Biological Barriers ◽  
Over Time

To understand how nanoparticles (NPs) interact with biological barriers and to ensure they maintain their integrity over time, it is crucial to study their in vivo pharmacokinetic (PK) profiles. Many methods of tracking have been used to describe the in vivo fate of NPs and to evaluate their PKs and structural integrity. However, they do not deliver the same level of information and this may cause misinterpretations. Here, the authors review and discuss the different methods for in vivo tracking of organic NPs. Among them, Förster resonance energy transfer (FRET) presents great potential to track NPs' integrity. However, FRET still requires validated methods to extract and quantify NPs in biological fluids and tissues.

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