Ultrafast Synthesis of Ultrasmall Poly(Vinylpyrrolidone)-Protected Bismuth Nanodots as a Multifunctional Theranostic Agent for In Vivo Dual-Modal CT/Photothermal-Imaging-Guided Photothermal Therapy

2017 ◽  
Vol 27 (35) ◽  
pp. 1702018 ◽  
Author(s):  
Pengpeng Lei ◽  
Ran An ◽  
Peng Zhang ◽  
Shuang Yao ◽  
Shuyan Song ◽  
...  
Small ◽  
2018 ◽  
Vol 14 (14) ◽  
pp. 1703789 ◽  
Author(s):  
Zhao-Hua Miao ◽  
Lan-Xiang Lv ◽  
Kai Li ◽  
Pei-Ying Liu ◽  
Zhenglin Li ◽  
...  

2018 ◽  
Vol 6 (23) ◽  
pp. 3914-3921 ◽  
Author(s):  
Tianzheng Wang ◽  
Siqi Li ◽  
Zhen Zou ◽  
Luo Hai ◽  
Xue Yang ◽  
...  

A zeolitic imidazolate framework-8-based indocyanine green theranostic agent was constructed for fluorescence imaging and photothermal therapy of tumors in vivo.


Nanoscale ◽  
2018 ◽  
Vol 10 (35) ◽  
pp. 16765-16774 ◽  
Author(s):  
Pengpeng Lei ◽  
Ran An ◽  
Xiaohua Zheng ◽  
Peng Zhang ◽  
Kaimin Du ◽  
...  

Ultrasmall PEI-AgBiS2 nanodots were synthesized using an ultra-facile strategy, which could be used as highly efficient cancer theranostic agent.


2013 ◽  
Vol 26 (12) ◽  
pp. 1886-1893 ◽  
Author(s):  
Liang Cheng ◽  
Jingjing Liu ◽  
Xing Gu ◽  
Hua Gong ◽  
Xiaoze Shi ◽  
...  

2017 ◽  
Vol 5 (2) ◽  
pp. 382-387 ◽  
Author(s):  
Yuping Yan ◽  
Qi Yang ◽  
Jie Wang ◽  
Hongyu Jin ◽  
Jing Wang ◽  
...  

We report a two-step process to construct heteropoly blue (HPB) doped polymer nanoparticles with efficient near-infrared (NIR) light absorption and photothermal conversion efficiency of ∼23%.


2021 ◽  
Author(s):  
Liping Zhang ◽  
Yun Geng ◽  
Lijuan Li ◽  
Xiaofan Tong ◽  
Shi Liu ◽  
...  

Iridium–porphyrin conjugates assembled in nanoparticles are photosensitizers that exhibit excellent photothermal imaging and synergistic PDT and PTT in vivo.


2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Songtao Zhang ◽  
Longhai Jin ◽  
Jianhua Liu ◽  
Yang Liu ◽  
Tianqi Zhang ◽  
...  

AbstractIn spite of the tumor microenvironments responsive cancer therapy based on Fenton reaction (i.e., chemodynamic therapy, CDT) has been attracted more attentions in recent years, the limited Fenton reaction efficiency is the important obstacle to further application in clinic. Herein, we synthesized novel FeO/MoS2 nanocomposites modified by bovine serum albumin (FeO/MoS2-BSA) with boosted Fenton reaction efficiency by the synergistic effect of co-catalyze and photothermal effect of MoS2 nanosheets triggered by the second near-infrared (NIR II) light. In the tumor microenvironments, the MoS2 nanosheets not only can accelerate the conversion of Fe3+ ions to Fe2+ ions by Mo4+ ions on their surface to improve Fenton reaction efficiency, but also endow FeO/MoS2-BSA with good photothermal performances for photothermal-enhanced CDT and photothermal therapy (PTT). Consequently, benefiting from the synergetic-enhanced CDT/PTT, the tumors are eradicated completely in vivo. This work provides innovative synergistic strategy for constructing nanocomposites for highly efficient CDT.


2014 ◽  
Vol 26 (48) ◽  
pp. 8210-8216 ◽  
Author(s):  
Mei Chen ◽  
Shaoheng Tang ◽  
Zhide Guo ◽  
Xiaoyong Wang ◽  
Shiguang Mo ◽  
...  

2021 ◽  
Vol 17 (2) ◽  
pp. 205-215
Author(s):  
Zhenbo Sun ◽  
Mingfang Luo ◽  
Jia Li ◽  
Ailing Wang ◽  
Xucheng Sun ◽  
...  

Imaging-guided cancer theranostic is a promising strategy for cancer diagnostic and therapeutic. Photodynamic therapy (PDT), as an approved treatment modality, is limited by the poor solubility and dispersion of photosensitizers (PS) in biological fluids. Herein, it is demonstrated that superparamagnetic iron oxide (SPIO)-based nanoparticles (SCFs), prepared by conjugated with Chlorin e6 (Ce6) and modified with folic acid (FA) on the surface, can be used as versatile drug delivery vehicles for effective PDT. The nanoparticles are great carriers for photosensitizer Ce6 with an extremely high loading efficiency. In vitro fluorescence imaging and in vivo magnetic resonance imaging (MRI) results indicated that SCFs selectively accumulated in tumor cells. Under near-infrared laser irradiation, SCFs were confirmed to be capable of inducing low cell viability of RM-1 cells In vitro and displaying efficient tumor ablation with negligible side effects in tumor-bearing mice models.


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