scholarly journals Multianchored Glycoconjugate-Functionalized Magnetic Nanoparticles: A Tool for Selective Killing of Targeted Bacteria via Alternating Magnetic Fields

2017 ◽  
Vol 27 (26) ◽  
pp. 1701473 ◽  
Author(s):  
Yash S. Raval ◽  
Benjamin D. Fellows ◽  
Jamie Murbach ◽  
Yves Cordeau ◽  
Olin Thompson Mefford ◽  
...  
2017 ◽  
Vol 233 (2) ◽  
pp. 1168-1178 ◽  
Author(s):  
Seongbeom Jeon ◽  
Ramesh Subbiah ◽  
Taufik Bonaedy ◽  
Seyoung Van ◽  
Kwideok Park ◽  
...  

ACS Nano ◽  
2013 ◽  
Vol 7 (6) ◽  
pp. 5091-5101 ◽  
Author(s):  
Maribella Domenech ◽  
Ileana Marrero-Berrios ◽  
Madeline Torres-Lugo ◽  
Carlos Rinaldi

2012 ◽  
Vol 48 (11) ◽  
pp. 3792-3795 ◽  
Author(s):  
Jan Henrik Dieckhoff ◽  
Takashi Yoshida ◽  
Keiji Enpuku ◽  
Meinhard Schilling ◽  
Frank Ludwig

Nanomaterials ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 627
Author(s):  
Felisa Reyes-Ortega ◽  
Ángel Delgado ◽  
Guillermo Iglesias

The use of magnetic nanoparticles in hyperthermia, that is, heating induced by alternating magnetic fields, is gaining interest as a non-invasive, free of side effects technique that can be considered as a co-adjuvant of other cancer treatments. Having sufficient control on the field characteristics, within admissible limits, the focus is presently on the magnetic material. In the present contribution, no attempt has been made of using other composition than superparamagnetic iron oxide nanoparticles (SPION), or of applying surface functionalization, which opens a wider range of choices. We have used a hydrothermal synthesis route that allows preparing SPION nanoparticles in the 40 nm size range, with spherical, cuboidal or rod-like shapes, by minor changes in the synthesis steps. The three kinds of particles (an attempt to produce star-shaped colloids yielded hematite) were demonstrated to have the magnetite (or maghemite) crystallinity. Magnetization cycles showed virtually no hysteresis and demonstrated the superparamagnetic nature of the particles, cuboidal ones displaying saturation magnetization comparable to bulk magnetite, followed by rods and spheres. The three types were used as hyperthermia agents using magnetic fields of 20 kA/m amplitude and frequency in the range 136–205 kHz. All samples demonstrated to be able to raise the solution temperature from room values to 45 °C in a mere 60 s. Not all of them performed the same way, though. Cuboidal magnetic nanoparticles (MNPs) displayed the maximum heating power (SAR or specific absorption rate), ranging in fact among the highest reported with these geometries and raw magnetite composition.


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