scholarly journals Cancer Therapy: Dendritic Platinum-Copper Alloy Nanoparticles as Theranostic Agents for Multimodal Imaging and Combined Chemophotothermal Therapy (Adv. Funct. Mater. 33/2016)

2016 ◽  
Vol 26 (33) ◽  
pp. 5950-5950 ◽  
Author(s):  
Zhengjie Zhou ◽  
Kewen Hu ◽  
Rui Ma ◽  
Yang Yan ◽  
Bing Ni ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Copper Alloy ◽  
Multimodal Imaging ◽  
Alloy Nanoparticles ◽  
Theranostic Agents

Dendritic Platinum-Copper Alloy Nanoparticles as Theranostic Agents for Multimodal Imaging and Combined Chemophotothermal Therapy

2016 ◽  
Vol 26 (33) ◽  
pp. 5971-5978 ◽  
Author(s):  
Zhengjie Zhou ◽  
Kewen Hu ◽  
Rui Ma ◽  
Yang Yan ◽  
Bing Ni ◽  
...  
Keyword(s):  
Copper Alloy ◽  
Multimodal Imaging ◽  
Alloy Nanoparticles ◽  
Theranostic Agents

scholarly journals Correction: A polydopamine-coated LAPONITE®-stabilized iron oxide nanoplatform for targeted multimodal imaging-guided photothermal cancer therapy

2021 ◽  
Vol 9 (10) ◽  
pp. 2549-2549
Author(s):  
Mengxue Liu ◽  
Jiulong Zhang ◽  
Xin Li ◽  
Chao Cai ◽  
Xueyan Cao ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Cancer Therapy ◽  
Multimodal Imaging

Correction for ‘A polydopamine-coated LAPONITE®-stabilized iron oxide nanoplatform for targeted multimodal imaging-guided photothermal cancer therapy’ by Mengxue Liu et al., J. Mater. Chem. B, 2019, 7, 3856–3864, DOI: 10.1039/c9tb00398c.

scholarly journals A Novel Top-Down Synthesis of Ultrathin 2D Boron Nanosheets for Multimodal Imaging-Guided Cancer Therapy

2018 ◽  
Vol 30 (36) ◽  
pp. 1803031 ◽  
Author(s):  
Xiaoyuan Ji ◽  
Na Kong ◽  
Junqing Wang ◽  
Wenliang Li ◽  
Yuling Xiao ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Multimodal Imaging ◽  
Top Down

scholarly journals Iron–gold alloy nanoparticles serve as a cornerstone in hyperthermia-mediated controlled drug release for cancer therapy

2018 ◽  
Vol Volume 13 ◽  
pp. 5499-5509 ◽  
Author(s):  
Yunqian Li ◽  
Meng Xu ◽  
Udesh Dhawan ◽  
Wai-Ching Liu ◽  
Kou-Ting Wu ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Drug Release ◽  
Gold Alloy ◽  
Controlled Drug Release ◽  
Alloy Nanoparticles

scholarly journals Synthesis and analysis of silver–copper alloy nanoparticles of different ratios manifest anticancer activity in breast cancer cells

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Sara Al Tamimi ◽  
Sarmadia Ashraf ◽  
Tahir Abdulrehman ◽  
Aijaz Parray ◽  
Said A. Mansour ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Death ◽  
Toxic Effect ◽  
Cancer Cells ◽  
Copper Alloy ◽  
Metallic Nanoparticles ◽  
Alloy Nanoparticles ◽  
Silver Copper ◽  
Transmission Electron ◽  
Mcf 7

Abstract Background Breast cancer is therapeutically very challenging to treat as it has the main four known genetic alterations, which result in the existence of several phenotypes leading to the difference in the mode of therapy and with poor outcome. Metallic nanoparticles of silver or copper have been studied previously as anticancer agents in breast cancer and other types of cancers. However, the anticancer effect of silver–copper alloy nanoparticles (AgCu-NP) is not studied in breast cancer. In this study, we aim to synthesize silver nanoparticles (Ag-NP), or copper nanoparticles (Cu-NP), and AgCu-NP and evaluate their toxicity in breast cancer and healthy breast cells. Results We synthesized sodium citrate and mercapto-propionic acid (MPA-3) capped water-soluble metallic nanoparticles of Ag-NP or Cu-NP and an alloy of three different combinations of AgCu-NP. High-resolution transmission electron microscopy characterization of nanoparticles revealed the spherical shape nanoparticles of varied sizes, furthermore dynamic light scattering characterization was performed, which investigated the hydrodynamic size and stability in phosphate buffer solution. Energy-dispersive X-ray spectroscopy (EDS) measurements were obtained from the transmission electron microscope to study the composition of alloy nanoparticles and the distribution pattern of silver and copper in the alloy nanoparticles. We measured the toxicity of nanoparticles to breast cancer MCF-7 cell line by MTT assay and compared the toxic effect with non-cancerous breast epithelial cells MCF-10A. Our data showed that Ag-NP or Cu-NP have no effect on cancer cells or healthy cells, except Ag-NP at 20 µg/ml were toxic to cancer cells. However, AgCu-NP were significantly toxic to MCF-7 cells at 10 µg/ml concentration, while as AgCu-NP have no toxic effect on healthy cells. Furthermore, we observed the cell death pathway by the apoptosis marker Annexin-V which showed non-significant results, while the exposure of AgCu-NP in MCF-7 cells leads to toxicity and also caused significant increase in MMP-9 level, which suggests the cell death may be associated with other pathways such as autophagy and oxidative stress related. Conclusion The data suggest that the AgCu-NP alloy imposes preferential toxicity in breast cancer MCF-7 cells and thus could be exploited as a new candidate for further anticancer investigation

pH/redox dual-stimuli-responsive cross-linked polyphosphazene nanoparticles for multimodal imaging-guided chemo-photodynamic therapy

Nanoscale ◽  
2019 ◽  
Vol 11 (19) ◽  
pp. 9457-9467 ◽  
Author(s):  
Xunan Jing ◽  
Zhe Zhi ◽  
Liming Jin ◽  
Fei Wang ◽  
Youshen Wu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Multimodal Imaging ◽  
Great Promise ◽  
Stimuli Responsive

Multifunctional nanodrugs with the integration of precise diagnostic and effective therapeutic functions have shown great promise in improving the efficacy of cancer therapy.

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