scholarly journals Induction of Potent Antitumor Immunity by Sustained Release of Cationic Antigen from a DNA-Based Hydrogel with Adjuvant Activity

2015 ◽  
Vol 25 (36) ◽  
pp. 5758-5767 ◽  
Author(s):  
Yuka Umeki ◽  
Kohta Mohri ◽  
Yohji Kawasaki ◽  
Hiroshi Watanabe ◽  
Rei Takahashi ◽  
...  
Keyword(s):  
Sustained Release ◽  
Antitumor Immunity ◽  
Adjuvant Activity ◽  
Cationic Antigen

1558: Local Injection of Sustained-Release Antiandrogen Formulation into a Target Prostatic Site: An Experimental Study

2007 ◽  
Vol 177 (4S) ◽  
pp. 515-515
Author(s):  
Nobuyuki Goya ◽  
Kotara Gotanda ◽  
Yasuko Tomizawa ◽  
Hiroshi Toma
Keyword(s):  
Experimental Study ◽  
Sustained Release ◽  
Local Injection

Pursuit of the Abscopal Effect

2020 ◽  
Vol 04 (04) ◽  
pp. 369-372
Author(s):  
Paul B. Romesser ◽  
Christopher H. Crane
Keyword(s):  
Tumor Immunology ◽  
Antitumor Immunity ◽  
Clinical Success ◽  
Immune Recognition ◽  
Immune Modulators ◽  
Cancer Subtypes ◽  
The Past ◽  
Tumor Irradiation ◽  
Wide Range ◽  
Tumor Recognition

AbstractEvasion of immune recognition is a hallmark of cancer that facilitates tumorigenesis, maintenance, and progression. Systemic immune activation can incite tumor recognition and stimulate potent antitumor responses. While the concept of antitumor immunity is not new, there is renewed interest in tumor immunology given the clinical success of immune modulators in a wide range of cancer subtypes over the past decade. One particularly interesting, yet exceedingly rare phenomenon, is the abscopal response, characterized by a potent systemic antitumor response following localized tumor irradiation presumably attributed to reactivation of antitumor immunity.

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