Gold Core-DNA-Silver Shell Nanoparticles with Intense Plasmonic Chiroptical Activities

2014 ◽  
Vol 25 (6) ◽  
pp. 850-854 ◽  
Author(s):  
Xiaoling Wu ◽  
Liguang Xu ◽  
Wei Ma ◽  
Liqiang Liu ◽  
Hua Kuang ◽  
...  
Keyword(s):  
Shell Nanoparticles ◽  
Gold Core ◽  
Silver Shell

SERS properties of gold core silver shell nanoparticles self-assembled on silica substrates and optical fiber endface

2012 ◽  
Author(s):  
Qianqian Geng ◽  
Zhenyi Chen ◽  
Na Chen ◽  
Shupeng Liu ◽  
Chen Qian ◽  
...  
Keyword(s):  
Optical Fiber ◽  
Shell Nanoparticles ◽  
Gold Core ◽  
Self Assembled ◽  
Silver Shell ◽  
Silica Substrates

Determination of trichloroethylene by using self-referenced SERS and gold-core/silver-shell nanoparticles

2018 ◽  
Vol 185 (7) ◽  
Author(s):  
Zhao Yu ◽  
Michael E. Smith ◽  
Jinnan Zhang ◽  
Yan Zhou ◽  
Peng Zhang
Keyword(s):  
Shell Nanoparticles ◽  
Gold Core ◽  
Silver Shell

scholarly journals Core–shell nanoparticles suppress metastasis and modify the tumour-supportive activity of cancer-associated fibroblasts

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Dávid Kovács ◽  
Nóra Igaz ◽  
Annamária Marton ◽  
Andrea Rónavári ◽  
Péter Bélteky ◽  
...  
Keyword(s):  
Tumour Microenvironment ◽  
Cancer Associated Fibroblasts ◽  
Malignant Cells ◽  
Tumour Stroma ◽  
Shell Nanoparticles ◽  
Stromal Fibroblasts ◽  
Metastatic Dissemination ◽  
Gold Core ◽  
Silver Shell

Abstract Background Although accumulating evidence suggests that the crosstalk between malignant cells and cancer-associated fibroblasts (CAFs) actively contributes to tumour growth and metastatic dissemination, therapeutic strategies targeting tumour stroma are still not common in the clinical practice. Metal-based nanomaterials have been shown to exert excellent cytotoxic and anti-cancerous activities, however, their effects on the reactive stroma have never been investigated in details. Thus, using feasible in vitro and in vivo systems to model tumour microenvironment, we tested whether the presence of gold, silver or gold-core silver-shell nanoparticles exerts anti-tumour and metastasis suppressing activities by influencing the tumour-supporting activity of stromal fibroblasts. Results We found that the presence of gold-core silver-shell hybrid nanomaterials in the tumour microenvironment attenuated the tumour cell-promoting behaviour of CAFs, and this phenomenon led to a prominent attenuation of metastatic dissemination in vivo as well. Mechanistically, transcriptome analysis on tumour-promoting CAFs revealed that silver-based nanomaterials trigger expressional changes in genes related to cancer invasion and tumour metastasis. Conclusions Here we report that metal nanoparticles can influence the cancer-promoting activity of tumour stroma by affecting the gene expressional and secretory profiles of stromal fibroblasts and thereby altering their intrinsic crosstalk with malignant cells. This potential of metal nanomaterials should be exploited in multimodal treatment approaches and translated into improved therapeutic outcomes.

The fate of nano-silver in aqueous media

Nanoscale ◽  
2015 ◽  
Vol 7 (29) ◽  
pp. 12361-12364 ◽  
Author(s):  
Blake. J. Plowman ◽  
Kristina Tschulik ◽  
Emily Walport ◽  
Neil P. Young ◽  
Richard G. Compton
Keyword(s):  
Chemical Stability ◽  
Aqueous Media ◽  
Electrochemical Analysis ◽  
Shell Nanoparticles ◽  
Nano Silver ◽  
Gold Core ◽  
Aqueous Environments ◽  
Silver Shell

The electrochemical analysis of gold-core silver-shell nanoparticles is demonstrated to provide a rigorous and effective method to probe the chemical stability of nano-silver in aqueous environments.

scholarly journals Nanoparticles: Gold Core-DNA-Silver Shell Nanoparticles with Intense Plasmonic Chiroptical Activities (Adv. Funct. Mater. 6/2015)

2015 ◽  
Vol 25 (6) ◽  
pp. 987-987 ◽  
Author(s):  
Xiaoling Wu ◽  
Liguang Xu ◽  
Wei Ma ◽  
Liqiang Liu ◽  
Hua Kuang ◽  
...  
Keyword(s):  
Shell Nanoparticles ◽  
Gold Core ◽  
Silver Shell
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