Vesicular Structures Self-Assembled from Oligonucleotide-Polymer Hybrids: Mechanical Prevention of Bacterial Colonization Upon their Surface Tethering Through Hybridization

2012 ◽  
Vol 22 (23) ◽  
pp. 4891-4898 ◽  
Author(s):  
Nicolas Cottenye ◽  
Karine Anselme ◽  
Lydie Ploux ◽  
Corinne Vebert-Nardin
2017 ◽  
Vol 75 (6) ◽  
pp. 2627-2639 ◽  
Author(s):  
Qi Cao ◽  
Naipu He ◽  
Yue Wang ◽  
Zhenwu Lu

Antibiotics ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1516
Author(s):  
Eskil André Karlsen ◽  
Wenche Stensen ◽  
Eric Juskewitz ◽  
Johan Svenson ◽  
Mattias Berglin ◽  
...  

Medical devices with an effective anti-colonization surface are important tools for combatting healthcare-associated infections. Here, we investigated the anti-colonization efficacy of antimicrobial peptides covalently attached to a gold model surface. The gold surface was modified by a self-assembled polyethylene glycol monolayer with an acetylene terminus. The peptides were covalently connected to the surface through a copper-catalyzed [3 + 2] azide-acetylene coupling (CuAAC). The anti-colonization efficacy of the surfaces varied as a function of the antimicrobial activity of the peptides, and very effective surfaces could be prepared with a 6 log unit reduction in bacterial colonization.


2020 ◽  
Vol 12 (19) ◽  
pp. 22237-22245
Author(s):  
Lu Liu ◽  
Xiao Xiao ◽  
Ke Li ◽  
Xia Li ◽  
Kang Yu ◽  
...  

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