scholarly journals Manufacturing and Characterization of Highly Porous Bioactive Glass Composite Scaffolds Using Unidirectional Freeze Casting

2017 ◽  
Vol 19 (10) ◽  
pp. 1700129 ◽  
Author(s):  
Laura M. Henning ◽  
Sara Zavareh ◽  
Paul H. Kamm ◽  
Miriam Höner ◽  
Horst Fischer ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Freeze Casting ◽  
Glass Composite ◽  
Composite Scaffolds ◽  
Highly Porous

Preparation and characterization of PHBV microsphere/45S5 bioactive glass composite scaffolds with vancomycin releasing function

2014 ◽  
Vol 41 ◽  
pp. 320-328 ◽  
Author(s):  
Wei Li ◽  
Yaping Ding ◽  
Ranjana Rai ◽  
Judith A. Roether ◽  
Dirk W. Schubert ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Glass Composite ◽  
Composite Scaffolds

scholarly journals Fabrication and in vitro characterization of bioactive glass composite scaffolds for bone regeneration

2013 ◽  
Vol 5 (4) ◽  
pp. 045005 ◽  
Author(s):  
Patrina S P Poh ◽  
Dietmar W Hutmacher ◽  
Molly M Stevens ◽  
Maria A Woodruff
Keyword(s):  
Bioactive Glass ◽  
Bone Regeneration ◽  
Glass Composite ◽  
Composite Scaffolds ◽  
In Vitro Characterization

Biomimetic characterization reveals enhancement of hydroxyapatite formation by fluid flow in gellan gum and bioactive glass composite scaffolds

2019 ◽  
Vol 76 ◽  
pp. 464-472 ◽  
Author(s):  
Jovana Zvicer ◽  
Ana Medic ◽  
Djordje Veljovic ◽  
Sanja Jevtic ◽  
Sasa Novak ◽  
...  
Keyword(s):  
Fluid Flow ◽  
Bioactive Glass ◽  
Gellan Gum ◽  
Glass Composite ◽  
Composite Scaffolds ◽  
Hydroxyapatite Formation

scholarly journals Effect of Melt-Derived Bioactive Glass Particles on the Properties of Chitosan Scaffolds

2019 ◽  
Vol 10 (3) ◽  
pp. 38 ◽  
Author(s):  
Hamasa Faqhiri ◽  
Markus Hannula ◽  
Minna Kellomäki ◽  
Maria Teresa Calejo ◽  
Jonathan Massera
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
Calcium Phosphate ◽  
Bioactive Glass ◽  
Pore Size ◽  
Glass Content ◽  
Micro Computed Tomography ◽  
Glass Composite ◽  
Composite Scaffolds ◽  
Bioactive Glasses

This study reports on the processing of three-dimensional (3D) chitosan/bioactive glass composite scaffolds. On the one hand, chitosan, as a natural polymer, has suitable properties for tissue engineering applications but lacks bioactivity. On the other hand, bioactive glasses are known to be bioactive and to promote a higher level of bone formation than any other biomaterial type. However, bioactive glasses are hard, brittle, and cannot be shaped easily. Therefore, in the past years, researchers have focused on the processing of new composites. Difficulties in reaching composite materials made of polymer (synthetic or natural) and bioactive glass include: (i) The high glass density, often resulting in glass segregation, and (ii) the fast bioactive glass reaction when exposed to moisture, leading to changes in the glass reactivity and/or change in the polymeric matrix. Samples were prepared with 5, 15, and 30 wt% of bioactive glass S53P4 (BonAlive ®), as confirmed using thermogravimetric analysis. MicrO–Computed tomography and optical microscopy revealed a flaky structure with porosity over 80%. The pore size decreased when increasing the glass content up to 15 wt%, but increased back when the glass content was 30 wt%. Similarly, the mechanical properties (in compression) of the scaffolds increased for glass content up to 15%, but decreased at higher loading. Ions released from the scaffolds were found to lead to precipitation of a calcium phosphate reactive layer at the scaffold surface. This is a first indication of the potential bioactivity of these materials. Overall, chitosan/bioactive glass composite scaffolds were successfully produced with pore size, machinability, and ability to promote a calcium phosphate layer, showing promise for bone tissue engineering and the mechanical properties can justify their use in non-load bearing applications.

Sign in / Sign up

Export Citation Format

Share Document