Cytotoxicity and Cell Cycle Effects of Bare and Poly(vinyl alcohol)-Coated Iron Oxide Nanoparticles in Mouse Fibroblasts

2009 ◽  
Vol 11 (12) ◽  
pp. B243-B250 ◽  
Author(s):  
Morteza Mahmoudi ◽  
Abdolreza Simchi ◽  
Hojatollah Vali ◽  
Mohammad Imani ◽  
Mohammad A. Shokrgozar ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Oxide Nanoparticles ◽  
Mouse Fibroblasts

scholarly journals Multiphysics Flow Modeling and in Vitro Toxicity of Iron Oxide Nanoparticles Coated with Poly(vinyl alcohol)

2009 ◽  
Vol 113 (6) ◽  
pp. 2322-2331 ◽  
Author(s):  
Morteza Mahmoudi ◽  
Mohammad A. Shokrgozar ◽  
Abdolreza Simchi ◽  
Mohammad Imani ◽  
Abbas S. Milani ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Vinyl Alcohol ◽  
In Vitro Toxicity ◽  
Poly Vinyl Alcohol ◽  
Oxide Nanoparticles ◽  
Flow Modeling

scholarly journals Multiphysics Flow Modeling and in Vitro Toxicity of Iron Oxide Nanoparticles Coated with Poly(vinyl alcohol)

2009 ◽  
Vol 113 (39) ◽  
pp. 17274-17274 ◽  
Author(s):  
Morteza Mahmoudi ◽  
Mohammad A. Shokrgozar ◽  
Abdolreza Simchi ◽  
Mohammad Imani ◽  
Abbas S. Milani ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Vinyl Alcohol ◽  
In Vitro Toxicity ◽  
Poly Vinyl Alcohol ◽  
Oxide Nanoparticles ◽  
Flow Modeling

Investigating SMART Membranes and Coatings by In Situ Synthesis of Iron Oxide Nanoparticles in PVA Hydrogels

2008 ◽  
Vol 60 ◽  
pp. 32-37 ◽  
Author(s):  
George K. Stylios ◽  
Tao Yu Wan
Keyword(s):  
Magnetic Properties ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Vinyl Alcohol ◽  
Calcium Alginate ◽  
Poly Vinyl Alcohol ◽  
Oxide Nanoparticles ◽  
Particle Nucleation ◽  
Iron Oxide Particles

This paper reports a novel method of developing SMART nanocomposite membranes and coatings by in situ synthesis of iron oxide particles in a Poly(vinyl alcohol) (PVA)matrix, using co-precipitation of different amounts of Fe(II) and Fe(III) taken in an alkaline medium. Poly(vinyl alcohol) was used to encapsulate iron oxide nanoparticles, as scaffold for particle nucleation and its influence on particle size and on magnetic properties were studied. The ferrogels were prepared by a freeze/thawing process of the solutions containing magnetite nanoparticles. Magnetite particles with an average diameter of 20-40 nm were obtained homogeneously within the matrix because of the tridimensional structure and chelating capacities of PVA. Calcium-alginate PVA gel was used to encapsulate the iron oxide/PVA nanocomposite. The mechanical properties and the saturation magnetization of the system were measured. The combination of magnetic properties of iron nanoparticles with the biocompatibility of calcium-alginate suggests that these materials have great potential for use as controlled delivery systems activated externally by magnetic stimuli.

Enhancing arsenic adsorption via excellent dispersion of iron oxide nanoparticles inside poly(vinyl alcohol) nanofibers

2020 ◽  
pp. 104664
Author(s):  
Nicolás Torasso ◽  
Alicia Vergara-Rubio ◽  
Patricia Rivas-Rojas ◽  
Cristián Huck-Iriart ◽  
Aitor Larrañaga ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Oxide Nanoparticles ◽  
Arsenic Adsorption

Superparamagnetic iron oxide nanoparticles enhance glioma radiosensitivity via inducing cell cycle arrest and apoptosis

2020 ◽  
Author(s):  
Jinning Mao ◽  
Meng Jiang ◽  
Xingliang Dai ◽  
Guodong Liu ◽  
Zhixiang Zhuang ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Glioma Cells ◽  
Superparamagnetic Iron Oxide ◽  
Spherical Shape ◽  
Treated Group ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
X Ray

Abstract Aim: Superparamagnetic iron oxide nanoparticles (SPIONs) is a widely used biomedical material for imaging and targeting drug delivery. We synthesized SPIONs and tested their effects on the radiosensitization of glioma.Methods: Acetylated 3-aminopropyltrimethoxysilane (APTS)-coated iron oxide nanoparticles (Fe3O4 NPs) were synthesized via a one-step hydrothermal approach and the surface was chemically modified with acetic anhydride to generate surface charge-neutralized NPs. NPs were characterized by TEM and ICP-AES. Radiosensitivity of U87MG glioma cells was evaluated by MTT assay. Cell cycle and apoptosis in glioma cells were examined by flow cytometry. Results: APTS-coated Fe3O4 NPs had a spherical or quasi-spherical shape with average size of 10.5±1.1 nm. NPs had excellent biocompatibility and intracellular uptake of NPs reached the peak 24 hours after treatment. U87 cell viability decreased significantly after treatment with both X-ray and NPs compared to X-ray treatment alone. Compared to X-ray treatment alone, the percentage of cells in G2/M phase (31.83%) significantly increased in APTS-coated Fe3O4 NPs plus X-ray treated group (P<0.05). In addition, the percentage of apoptotic cells was significant higher in APTS-coated Fe3O4 NPs plus X-ray treated group than in X-ray treatment alone group (P<0.05). Conclusion: APTS-coated Fe3O4 NPs achieved excellent biocompatibility and increased radiosensitivity for glioma cells.

Iron Oxide Nanoparticles Induces Cell Cycle-Dependent Neuronal Apoptosis in Mice

2018 ◽  
Vol 64 (3) ◽  
pp. 352-362 ◽  
Author(s):  
Vijayprakash Manickam ◽  
Vasanth Dhakshinamoorthy ◽  
Ekambaram Perumal
Keyword(s):  
Cell Cycle ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Neuronal Apoptosis ◽  
Oxide Nanoparticles ◽  
Cycle Dependent
Sign in / Sign up

Export Citation Format

Share Document