Hydroxyapatite/Bioactive Glass Films Produced by a Sol–Gel Method: In Vitro Behavior

2009 ◽  
Vol 11 (11) ◽  
pp. B194-B199 ◽  
Author(s):  
Nihat C. Köseoğlu ◽  
Aligül Büyükaksoy ◽  
Ahmet Y. Oral ◽  
Muhammed H. Aslan
Keyword(s):  
Bioactive Glass ◽  
Gel Method ◽  
Glass Films

scholarly journals Simple and Acid-Free Hydrothermal Synthesis of Bioactive Glass 58SiO2-33CaO-9P2O5 (wt%)

Crystals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 283
Author(s):  
Ta Anh Tuan ◽  
Elena V. Guseva ◽  
Nguyen Anh Tien ◽  
Ho Tan Dat ◽  
Bui Xuan Vuong
Keyword(s):  
Bioactive Glass ◽  
Inductively Coupled Plasma ◽  
Sol Gel ◽  
Hydrothermal Process ◽  
Optical Emission ◽  
Emission Spectrometry ◽  
Ionic Exchange ◽  
Gel Method ◽  
Sol Gel Method

The paper focuses on the acid-free hydrothermal process for the synthesis of bioactive glass. The new method avoids the use of harmful acid catalysts, which are usually used in the sol-gel process. On the other hand, the processing time was reduced compared with the sol-gel method. A well-known ternary bioactive glass 58SiO2-33CaO-9P2O5 (wt%), which has been widely synthesized through the sol-gel method, was selected to apply to this new process. Thermal behavior, textural property, phase composition, morphology, and ionic exchange were investigated by thermal analysis, N2 adsorption/desorption, XRD, FTIR, SEM, and inductively coupled plasma optical emission spectrometry (ICP-OES) analysis. The bioactivity and biocompatibility of synthetic bioactive glass were evaluated by in vitro experiments with a simulated body fluid (SBF) solution and cell culture medium. The obtained results confirmed that the acid-free hydrothermal process is one of the ideal methods for preparing ternary bioactive glass.

Fabrication of Mesoporous Bioactive Glass Nanoparticles by Sol-Gel Method

2018 ◽  
Vol 765 ◽  
pp. 136-139
Author(s):  
Wei Wen Lin ◽  
Wei Fang ◽  
I Hao Chen ◽  
Tze Yo Hung ◽  
Chih Ling Huang
Keyword(s):  
Electron Microscopy ◽  
Bioactive Glass ◽  
Sol Gel ◽  
Tumor Resection ◽  
Gel Method ◽  
Sol Gel Method ◽  
Ph Values ◽  
Transmission Electron ◽  
Mesoporous Bioactive Glass

Bioactive glass (BG) is characteristic of its great biocompatibility as well as osteoconductivity. Application of BG after surgery (e.g., tumor resection) aids rehabilitation of previously traumatized area, promotes bone regeneration, and prevents aggravation of wounds. In this in vitro study, bioglass nanoparticles (BGN) were successfully produced via sol-gel method. We observed the morphology of BGN through Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM). Particle size was measured by Dynamic Light Scattering (DLS): 182.9 nm ± 37.7 nm in diameter, which corresponds to images obtained by SEM and TEM. We then synthesized BGs containing different proportions of Ca and P ions. Under different pH values, gels with various morphologies were formed.

scholarly journals Bioactive glass S53P4 eradicates Staphylococcus aureus in biofilm/planktonic states in vitro

2020 ◽  
Vol 125 (3) ◽  
pp. 217-225
Author(s):  
Torstein Grønseth ◽  
Lene K. Vestby ◽  
Live L. Nesse ◽  
Magnus von Unge ◽  
Juha T. Silvola
Keyword(s):  
Staphylococcus Aureus ◽  
Bioactive Glass

scholarly journals Synthesis, characterization and in vitro cytotoxicity study of Co and Ni ferrite nanoparticles prepared by sol-gel method

2021 ◽  
Vol 3 (7) ◽  
Author(s):  
Alexandre Pancotti ◽  
Dener Pereira Santos ◽  
Dielly Oliveira Morais ◽  
Mauro Vinícius de Barros Souza ◽  
Débora R. Lima ◽  
...  
Keyword(s):  
Photoelectron Spectroscopy ◽  
Sol Gel ◽  
Test Sample ◽  
In Vitro Cytotoxicity ◽  
Gel Method ◽  
X Ray ◽  
Sol Gel Method ◽  
Transmission Electron ◽  
Crystallite Sizes

AbstractIn this study, we report the synthesis and characterization of NiFe2O4 and CoFe2O4 nanoparticles (NPs) which are widely used in the biomedical area. There is still limited knowledge how the properties of these materials are influenced by different chemical routes. In this work, we investigated the effect of heat treatment over cytotoxicity of cobalt and niquel ferrites NPs synthesized by sol-gel method. Then the samples were studied using transmission electron microscopy (TEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), vibrating sample magnetometer (VSM), Fourier Transform Infrared Spectroscopy Analysis (FTIR), and X-ray fluorescence (XRF). The average crystallite sizes of the particles were found to be in the range of 20–35 nm. The hemocompatibility (erythrocytes and leukocytes) was checked. Cytotoxicity results were similar to those of the control test sample, therefore suggesting hemocompatibility of the tested materials.

scholarly journals Synthesis and Characterization of Silver–Strontium (Ag-Sr)-Doped Mesoporous Bioactive Glass Nanoparticles

Gels ◽  
2021 ◽  
Vol 7 (2) ◽  
pp. 34
Author(s):  
Shaher Bano ◽  
Memoona Akhtar ◽  
Muhammad Yasir ◽  
Muhammad Salman Maqbool ◽  
Akbar Niaz ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Composite Coatings ◽  
Antibacterial Properties ◽  
Bone Diseases ◽  
Osteogenic Potential ◽  
Diffusion Method ◽  
Charge Composition ◽  
In Vitro Bioactivity ◽  
Mesoporous Bioactive Glass

Biomedical implants are the need of this era due to the increase in number of accidents and follow-up surgeries. Different types of bone diseases such as osteoarthritis, osteomalacia, bone cancer, etc., are increasing globally. Mesoporous bioactive glass nanoparticles (MBGNs) are used in biomedical devices due to their osteointegration and bioactive properties. In this study, silver (Ag)- and strontium (Sr)-doped mesoporous bioactive glass nanoparticles (Ag-Sr MBGNs) were prepared by a modified Stöber process. In this method, Ag+ and Sr2+ were co-substituted in pure MBGNs to harvest the antibacterial properties of Ag ions, as well as pro-osteogenic potential of Sr2 ions. The effect of the two-ion concentration on morphology, surface charge, composition, antibacterial ability, and in-vitro bioactivity was studied. Scanning electron microscopy (SEM), X-Ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR) confirmed the doping of Sr and Ag in MBGNs. SEM and EDX analysis confirmed the spherical morphology and typical composition of MBGNs, respectively. The Ag-Sr MBGNs showed a strong antibacterial effect against Staphylococcus carnosus and Escherichia coli bacteria determined via turbidity and disc diffusion method. Moreover, the synthesized Ag-Sr MBGNs develop apatite-like crystals upon immersion in simulated body fluid (SBF), which suggested that the addition of Sr improved in vitro bioactivity. The Ag-Sr MBGNs synthesized in this study can be used for the preparation of scaffolds or as a filler material in the composite coatings for bone tissue engineering.

scholarly journals Mesoporous Properties of Bioactive Glass Synthesized by Spray Pyrolysis with Various Polyethylene Glycol and Acid Additions

Polymers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 618
Author(s):  
Tzu-Yu Peng ◽  
Pei-Yun Tsai ◽  
May-Show Chen ◽  
Yuichi Mine ◽  
Shan-Hua Wu ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Polyethylene Glycol ◽  
Bioactive Glass ◽  
Spray Pyrolysis ◽  
Mesoporous Structure ◽  
High Specific Surface Area ◽  
Process Time ◽  
In Vitro Bioactivity ◽  
One Pot

Mesoporous bioactive glass (MBG) has a high specific surface area, promoting the reaction area, thereby improving the bioactivity; thus, MBG is currently gaining popularity in the biomaterial field. Spray pyrolysis (SP) is a one-pot process that has the advantages of shorter process time and better particle bioactivity, therefore, MBG was prepared by SP process with various polyethylene glycol (PEG, molecular weight ranged from 2000–12,000) and acid (HCl and CH3COOH) additions. In vitro bioactivity and mesoporous properties of the so-obtained MBG were investigated. The experimental results showed that all the MBG exhibited amorphous and mesoporous structure. Increasing the molecular weight of PEG can improve the mesoporous structure and bioactivity of MBG. Whereas optimized MBG was prepared with suitable concentration of PEG and CH3COOH. In the present work, MBG synthesized via spray pyrolysis by adding 5 g of PEG with a molecular weight of 12,000 and 50 mL of CH3COOH exhibited the best in vitro bioactivity and mesoporous structure.

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