Microfluidics Cell Loading-Dock System: Ordered Cellular Array for Dynamic Lymphocyte-Communication Study

2017 ◽  
Vol 1 (10) ◽  
pp. 1700085 ◽  
Author(s):  
Ying Li ◽  
Joon Hee Jang ◽  
Crystal Wang ◽  
Bangshun He ◽  
Kai Zhang ◽  
...  
Keyword(s):  
Cell Loading ◽  
Cellular Array ◽  
Communication Study

A novel Josephson cellular array

1995 ◽  
Vol 5 (2) ◽  
pp. 3329-3332
Author(s):  
M. Morisue ◽  
Fu-Qiang Li
Keyword(s):  
Cellular Array

Design of a Bio-Inspired Embryonic Cellular Array Based on Bus Structure

2019 ◽  
Vol 29 (06) ◽  
pp. 2050099
Author(s):  
Tao Wang ◽  
Jinyan Cai ◽  
Yafeng Meng ◽  
Meng Lv ◽  
Zexi Li
Keyword(s):  
Large Scale ◽  
Evaluation Model ◽  
Functional Differentiation ◽  
Digital Circuit ◽  
Resource Consumption ◽  
Internal Communication ◽  
Oxide Semiconductor ◽  
Cellular Array ◽  
Hardware Resource ◽  
Bus Structure

There are some shortcomings, such as huge hardware resource consumption, functional differentiation is difficult and limited fault detection coverage, when embryonic cellular array (ECA) is used to design large-scale circuit. In this paper, the structure characteristics and communication method of multicellular organism are analyzed briefly, and a new bio-inspired ECA based on bus structure (BECA) is proposed, besides that the corresponding self-repairing strategy is designed. First, the functional decomposition has been applied in BECA, which uses bus structure to realize internal communication. BECA consists of bus and electronic tissues (ET), which can be used to realize large-scale circuit. C17 circuit in ISCAS85 circuit library is chosen as experiment subject, and experiment simulation results indicate that BECA based on bus structure is suitable for large-scale circuit, and the faults occurred in ET can be repaired effectively. In order to research BECA from the mathematical point of view, the reliability evaluation model of BECA is established, which is based on [Formula: see text]-out-of-[Formula: see text] system reliability model. In addition, the hardware resource consumption model of BECA is established by analyzing the number of metal oxide semiconductor (MOS) transistors that ECA consumed. Based on BECA reliability and hardware resource consumption evaluation model, comparative experiment is studied, and the results indicate that the proposed ECA can improve the reliability of circuit and reduce hardware resource consumption effectively. Therefore, the BECA presented will play an important role in designing large-scale digital circuit with self-repairing ability.

scholarly journals New avenues for systematically inferring cell-cell communication: through single-cell transcriptomics data

2020 ◽  
Vol 11 (12) ◽  
pp. 866-880 ◽  
Author(s):  
Xin Shao ◽  
Xiaoyan Lu ◽  
Jie Liao ◽  
Huajun Chen ◽  
Xiaohui Fan
Keyword(s):  
Single Cell ◽  
Communication Networks ◽  
Cell Communication ◽  
Receptor Interaction ◽  
Communication Studies ◽  
Transcriptomics Data ◽  
Phenotype Heterogeneity ◽  
Multicellular Organisms ◽  
Communication Study ◽  
Cell Cell

AbstractFor multicellular organisms, cell-cell communication is essential to numerous biological processes. Drawing upon the latest development of single-cell RNA-sequencing (scRNA-seq), high-resolution transcriptomic data have deepened our understanding of cellular phenotype heterogeneity and composition of complex tissues, which enables systematic cell-cell communication studies at a single-cell level. We first summarize a common workflow of cell-cell communication study using scRNA-seq data, which often includes data preparation, construction of communication networks, and result validation. Two common strategies taken to uncover cell-cell communications are reviewed, e.g., physically vicinal structure-based and ligand-receptor interaction-based one. To conclude, challenges and current applications of cell-cell communication studies at a single-cell resolution are discussed in details and future perspectives are proposed.

A large scale cellular array processor

1985 ◽  
Author(s):  
Toshio Kondo ◽  
Tayoshi Nakashima ◽  
Toshio Tsuchiya ◽  
Yoshi Sugiyama ◽  
Tsuneta Sudo
Keyword(s):  
Large Scale ◽  
Array Processor ◽  
Cellular Array
Sign in / Sign up

Export Citation Format

Share Document