scholarly journals Measures of Juvenile Fibromyalgia

2020 ◽  
Vol 72 (S10) ◽  
pp. 171-182
Author(s):  
Morgan Daffin ◽  
Robert C. Gibler ◽  
Susmita Kashikar‐Zuck
Keyword(s):  
Juvenile Fibromyalgia

Randomized clinical trial of Fibromyalgia Integrative Training (FIT teens) for adolescents with juvenile fibromyalgia – Study design and protocol

2021 ◽  
Vol 103 ◽  
pp. 106321
Author(s):  
Susmita Kashikar-Zuck ◽  
Matthew S. Briggs ◽  
Sharon Bout-Tabaku ◽  
Mark Connelly ◽  
Morgan Daffin ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Study Design ◽  
Juvenile Fibromyalgia

Juvenile Fibromyalgia Syndrome

2001 ◽  
Vol 21 (1) ◽  
pp. 19-36 ◽  
Author(s):  
G. Ted Brown ◽  
Rachelle Delisle ◽  
Nathalie Gagnon ◽  
Anne-Elise Sauve
Keyword(s):  
Fibromyalgia Syndrome ◽  
Juvenile Fibromyalgia

Epidermal Neurite Density in Skin Biopsies from Patients with Juvenile Fibromyalgia

2020 ◽  
pp. jrheum.200378
Author(s):  
Alexis Boneparth ◽  
Shan Chen ◽  
Daniel B. Horton ◽  
L. Nandini Moorthy ◽  
Ian Farquhar ◽  
...  
Keyword(s):  
Functional Disability ◽  
Meta Analysis ◽  
Skin Surface ◽  
Lower Leg ◽  
Healthy Controls ◽  
Juvenile Fibromyalgia ◽  
Neurite Density ◽  
American College Of Rheumatology ◽  
Small Fiber ◽  
Diagnostic Threshold

Objective Fibromyalgia is defined by idiopathic, chronic, widespread musculoskeletal pain. In adults with fibromyalgia, meta-analysis of lower-leg skin biopsy demonstrated 45% pooled prevalence of abnormally low epidermal neurite density (END). END <5th centile of the normal distribution is the consensus diagnostic threshold for small-fiber neuropathy. However, the clinical significance of END findings in fibromyalgia is unknown. The prevalence of small fiber pathology has not yet been studied in juvenile fibromyalgia. Methods We screened 21 patients aged 13-20y with fibromyalgia diagnosed by pediatric rheumatologists. Fifteen meeting the American College of Rheumatology criteria (modified for juvenile fibromyalgia) underwent lower-leg measurements of END and completed validated questionnaires assessing pain, functional disability, and dysautonomia symptoms. The primary outcome was proportion of fibromyalgia patients with END <5th centile of age/gender/race-based laboratory norms. Cases were systematically matched by ethnicity, race, sex, and age to a group of previously biopsied healthy adolescents with selection blinded to biopsy results. All 23 controls matching demographic criteria were included. Results Among biopsied JFM patients, 53% (8/15) had END <5th centile versus 4% (1/23) of healthy controls (p<0.001). Mean patient END was 273/mm2 skin surface (95% confidence interval: 198-389) versus 413 (95% CI: 359-467; p<0.001). As expected, fibromyalgia patients reported more functional disability, dysautonomia, and pain than healthy controls. Conclusion Abnormal END reduction is common in adolescents with fibromyalgia, with similar prevalence to adults with fibromyalgia. More studies are needed to fully characterize the significance of low END in fibromyalgia and to elucidate the clinical implications of these findings.

scholarly journals A pilot study of biomechanical assessment before and after an integrative training program for adolescents with juvenile fibromyalgia

2016 ◽  
Vol 14 (1) ◽  
Author(s):  
Susan T. Tran ◽  
Staci Thomas ◽  
Christopher DiCesare ◽  
Megan Pfeiffer ◽  
Soumitri Sil ◽  
...  
Keyword(s):  
Pilot Study ◽  
Training Program ◽  
Juvenile Fibromyalgia ◽  
Biomechanical Assessment ◽  
Before And After

scholarly journals Relationship between School Absenteeism and Depressive Symptoms among Adolescents with Juvenile Fibromyalgia

2010 ◽  
Vol 35 (9) ◽  
pp. 996-1004 ◽  
Author(s):  
S. Kashikar-Zuck ◽  
M. Johnston ◽  
T. V. Ting ◽  
B. T. Graham ◽  
A. M. Lynch-Jordan ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
School Absenteeism ◽  
Juvenile Fibromyalgia
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