scholarly journals Impact of Antiinflammatory Treatment on the Onset of Uveitis in Juvenile Idiopathic Arthritis: Longitudinal Analysis From a Nationwide Pediatric Rheumatology Database

2015 ◽  
Vol 68 (1) ◽  
pp. 46-54 ◽  
Author(s):  
Christoph Tappeiner ◽  
Sandra Schenck ◽  
Martina Niewerth ◽  
Arnd Heiligenhaus ◽  
Kirsten Minden ◽  
...  
2019 ◽  
Author(s):  
ICARO CRUZ SILVA ◽  
MARILIA VIEIRA FEBRÔNIO ◽  
WILLIAN MORORO LIMA ◽  
LUANN SOARES NUNES ◽  
PAULO ANTONIO DAMIÃO SANTOS ◽  
...  

2019 ◽  
Vol 86 (6) ◽  
pp. 739-745 ◽  
Author(s):  
Caroline Freychet ◽  
Céline Lambert ◽  
Bruno Pereira ◽  
Jean L. Stephan ◽  
Stéphane Echaubard ◽  
...  

2014 ◽  
Vol 66 ◽  
pp. S235-S236 ◽  
Author(s):  
Stacy P. Ardoin ◽  
C. April Bingham ◽  
Beth S. Gottlieb ◽  
Ronald M. Laxer ◽  
Murray H. Passo ◽  
...  

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Ashley M. Cooper ◽  
Elaine R. Flanagan ◽  
Tova Ronis ◽  
Baruch Goldberg ◽  
Ashley K. Sherman ◽  
...  

Abstract Background Chronic anterior uveitis is a sight-threatening complication of juvenile idiopathic arthritis (JIA) and a primary contributor to long-term morbidity in people with JIA. Levels of knowledge about uveitis among JIA patients and their parents are unknown. A survey of JIA patients and parents was conducted to assess knowledge about uveitis complications and recommended screening. Methods A survey was developed consisting of six demographic questions, six arthritis/uveitis history questions, and nine uveitis knowledge questions. The survey was administered to JIA patients age 14 and older and parents of patients with JIA at three pediatric rheumatology practices and online through the Patients, Advocates, and Rheumatology Teams Network for Research and Service (PARTNERS) network. ANOVA, chi-square and Fisher’s exact tests were used to look for relationships between survey questions and demographic variables. Results Thirty-three patients and 111 parents completed the survey. Overall, 17.4% reported a history of uveitis, and 89.6% had heard of uveitis. The mean composite knowledge score was 6.46 ± 2.6 out of 9. Patients and parents with a history of uveitis had higher composite knowledge scores than their counterparts without a uveitis history (p = 0.01 and p < 0.01, respectively). Parents whose rheumatologist reminded them about eye exams at every visit had higher knowledge of the risk of blindness (p = 0.04), the risk for uveitis when arthritis is controlled (p = 0.02), the need for ongoing eye exams when off of medications (p = 0.01), and had a higher overall score (p = 0.02) than those who were reminded at some visits or not at all. Conclusions JIA patients and parents report variable levels of knowledge regarding uveitis complications and recommended screening. Frequent discussion between the rheumatology provider and family about uveitis screening is associated with higher uveitis knowledge. Incorporating detailed and frequent education about uveitis into rheumatology clinic appointments may improve early uveitis detection and visual outcomes.


2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Sezgin Sahin ◽  
Ceyhun Acari ◽  
Hafize Emine Sonmez ◽  
Fatma Zehra Kilic ◽  
Erdal Sag ◽  
...  

Abstract Background Juvenile idiopathic arthritis (JIA), is the most common pediatric rheumatologic disorder with unknown etiology. Currently, no population-based data are available regarding the distribution of categories and frequency of uveitis in patients with JIA in Turkey. The purpose of this study was to evaluate the frequency of JIA-associated uveitis (JIAU) and distribution of JIA categories in a Turkish JIA cohort. Methods This was a retrospective study of 500 randomized patients in four pediatric rheumatology clinics in Turkey. Results Oligoarticular JIA (oJIA) was the most common JIA disease category in this study cohort (38.8%). The frequencies of the other categories were as follows: enthesitis-related arthritis (ERA), 23.2%; rheumatoid factor (RF)–negative polyarthritis, 15.6%; systemic arthritis, 12.2%; juvenile psoriatic arthritis, 5.2%; undifferentiated arthritis, 2.8%; and RF-positive polyarthritis, 2.2%. JIA-associated uveitis was observed in 6.8% of patients at a mean (Standard Deviation, SD) age of 9.1 (3.8) years over a mean JIA disease duration of 4 (1.9) years. Uveitis developed after joint disease, with a mean (SD) duration of 1.8 (1.9) years. Patients with oJIA had the highest rate of uveitis (12.9%) followed by patients with ERA (5.2%) and polyarticular RF-negative disease (3.8%). Compared with persistent oJIA, the extended oJIA category had a > 3-fold higher risk of uveitis (11.3% vs 27.7%; odds ratio, 3.38 [95% Confidence Interval, 1.09–10.4]). The most frequently administered drug after development of uveitis was tumor necrosis factor–alpha inhibitors (38.2%). Five patients (14.7%) had uveitis-related complications that required surgical intervention. Conclusions Turkish pediatric patients with JIA experience a lower frequency of oJIA and higher frequency of ERA than their white European counterparts; the occurrence of uveitis is also somewhat lower than expected. Geographic and ethnic factors may affect these differences and need further investigation.


2020 ◽  
Author(s):  
Sulaiman M Al‐Mayouf ◽  
Soad Hashad ◽  
Khulood Khawaja ◽  
Abeer Alrasheedi ◽  
Reem Abdwani ◽  
...  

2020 ◽  
pp. jrheum.200492 ◽  
Author(s):  
Randy Q. Cron ◽  
W. Winn Chatham

We appreciate our Italian colleagues’ interest in our editorial denoting the rheumatologist’s role in helping to diagnose and treat cytokine storm syndrome (CSS) in the setting of the Covid-19 panemic (1). It is encouraging that none of the 123 pediatric rheumatology patients (primarily juvenile idiopathic arthritis) on background biological disease modifying anti-rheumatic drug (bDMARD) therapies in Milan, Italy surveyed over a 7-week period from February 25 through April 14, 2020 (during which time Covid-19 was hyper-endemic there) had either confirmed or suspected Covid-19 (2).


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