scholarly journals Association of Tobacco Exposure and Reduction of Radiographic Progression in Early Rheumatoid Arthritis: Results From a French Multicenter Cohort

2013 ◽  
Vol 65 (12) ◽  
pp. 1899-1906 ◽  
Author(s):  
Veronique Vesperini ◽  
Cedric Lukas ◽  
Bruno Fautrel ◽  
Xavier Le Loet ◽  
Nathalie Rincheval ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Early Rheumatoid Arthritis ◽  
Radiographic Progression ◽  
Tobacco Exposure ◽  
Multicenter Cohort

MRI in early rheumatoid arthritis: synovitis and bone marrow oedema are independent predictors of subsequent radiographic progression

2010 ◽  
Vol 70 (3) ◽  
pp. 428-433 ◽  
Author(s):  
Pernille Bøyesen ◽  
Espen A Haavardsholm ◽  
Mikkel Østergaard ◽  
Désirée van der Heijde ◽  
Sølve Sesseng ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Marrow ◽  
Early Rheumatoid Arthritis ◽  
Radiographic Progression ◽  
Bone Marrow Oedema ◽  
Tender Joint Count ◽  
X Rays ◽  
Tender Joint ◽  
Reactive Protein

ObjectivesTo determine whether MRI and conventional (clinical and laboratory) measures of inflammation can predict 3-year radiographic changes measured by the van der Heijde Sharp score in patients with early rheumatoid arthritis (RA).Methods55 patients with RA with disease duration <1 year participated in this 3-year follow-up study. Patients were evaluated at baseline, 3, 6, 12 and 36 months by swollen and tender joint count, disease activity score based on 28-joint count, erythrocyte sedimentation rate (ESR), C reactive protein, MRI measures of synovitis, bone marrow oedema and tenosynovitis of the dominant wrist, as well as conventional x-rays of the hands and wrists.ResultsAll measures of inflammation decreased during the follow-up period. ESR, MRI synovitis and MRI bone marrow oedema were independent predictors of 3-year radiographic progression adjusted for age, sex and anti-citrullinated protein antibodies. The 1-year cumulative measures of MRI synovitis and bone marrow oedema provided an improved explanation of variation (adjusted R2) in radiographic change compared with the baseline MRI values (adjusted R2=0.32 and 0.20 vs 0.11 and 0.04, respectively).ConclusionsBoth baseline and 1-year cumulative measures of MRI synovitis and bone marrow oedema independently predicted 3-year radiographic progression. These results confirm that MRI synovitis and MRI bone marrow oedema precede radiographic progression in patients with early RA.

scholarly journals The interleukin-20 receptor axis in early rheumatoid arthritis: novel links between disease-associated autoantibodies and radiographic progression

2016 ◽  
Vol 18 (1) ◽  
Author(s):  
Tue Wenzel Kragstrup ◽  
Stinne Ravn Greisen ◽  
Morten Aagaard Nielsen ◽  
Christopher Rhodes ◽  
Kristian Stengaard-Pedersen ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Early Rheumatoid Arthritis ◽  
Radiographic Progression

Radiographic progression in early rheumatoid arthritis: Comment on the article by Goronzy et al

2004 ◽  
Vol 50 (9) ◽  
pp. 3052-3053
Author(s):  
Raimon Sanmarti ◽  
Antoni Gómez-Centeno ◽  
Jordi Gratacós ◽  
Juan D. Cañete
Keyword(s):  
Rheumatoid Arthritis ◽  
Early Rheumatoid Arthritis ◽  
Radiographic Progression

scholarly journals Serum cotinine as a biomarker of tobacco exposure and the association with treatment response in early rheumatoid arthritis

2012 ◽  
Vol 64 (12) ◽  
pp. 1804-1810 ◽  
Author(s):  
Leann B. Maska ◽  
Harlan R. Sayles ◽  
James R. O'Dell ◽  
Jeffrey R. Curtis ◽  
S. Louis Bridges ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Treatment Response ◽  
Early Rheumatoid Arthritis ◽  
Tobacco Exposure ◽  
Serum Cotinine
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