scholarly journals Serum free light chains as biomarkers for systemic lupus erythematosus disease activity

2011 ◽  
Vol 63 (6) ◽  
pp. 891-898 ◽  
Author(s):  
Rohit Aggarwal ◽  
Winston Sequeira ◽  
Rediet Kokebie ◽  
Rachel A. Mikolaitis ◽  
Lewis Fogg ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Disease Activity ◽  
Lupus Erythematosus ◽  
Light Chains ◽  
Systemic Lupus Erythematosus Disease ◽  
Systemic Lupus ◽  
Free Light Chains ◽  
Serum Free ◽  
Serum Free Light Chains

Serum free light chains, interferon-alpha, and interleukins in systemic lupus erythematosus

Lupus ◽  
2014 ◽  
Vol 23 (9) ◽  
pp. 881-888 ◽  
Author(s):  
M Jolly ◽  
S Francis ◽  
R Aggarwal ◽  
RA Mikolaitis ◽  
TB Niewold ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Interferon Alpha ◽  
Lupus Erythematosus ◽  
Light Chains ◽  
Systemic Lupus ◽  
Free Light Chains ◽  
Serum Free ◽  
Serum Free Light Chains

THU0339 Serum Free Light Chains: Activity Marker for Systemic Lupus Erythematosus

2013 ◽  
Vol 72 (Suppl 3) ◽  
pp. A279.4-A280
Author(s):  
J. J. Jimenez ◽  
L. Campos ◽  
N. Barbosa de Carvalho ◽  
C. Hernando de Larramendi
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Light Chains ◽  
Systemic Lupus ◽  
Free Light Chains ◽  
Serum Free ◽  
Activity Marker ◽  
Serum Free Light Chains

scholarly journals FRI0344 Serum free light chains as a flare biomarker in systemic lupus erythematosus

2018 ◽  
Author(s):  
A.B. Rodriguez Cambron ◽  
J. Jimenez Jimenez ◽  
M.A. Blazquez Cañamero ◽  
M.J. García De Yébenes ◽  
F. Rey Pazos ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Light Chains ◽  
Systemic Lupus ◽  
Free Light Chains ◽  
Serum Free ◽  
Serum Free Light Chains

scholarly journals A Comparison of the Correlation of Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) and Systemic Lupus Erythematosus Disease Activity Score (SLE-DAS) with Health-Related Quality of Life

2021 ◽  
Vol 10 (10) ◽  
pp. 2137
Author(s):  
Ning-Sheng Lai ◽  
Ming-Chi Lu ◽  
Hsiu-Hua Chang ◽  
Hui-Chin Lo ◽  
Chia-Wen Hsu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systemic Lupus Erythematosus ◽  
Disease Activity ◽  
Lupus Erythematosus ◽  
Activity Index ◽  
Disease Activity Index ◽  
Information Criterion ◽  
Systemic Lupus Erythematosus Disease ◽  
Systemic Lupus

Background and Aim: The aim of this study was to compare the correlation of a recently developed systemic lupus erythematosus disease activity score (SLE-DAS) with the SLE disease activity index 2000 (SLEDAI-2K) with the Lupus Quality of Life questionnaire (LupusQoL) in Taiwanese patients with SLE. Methods: A cross-sectional study was conducted in a regional teaching hospital in Taiwan from April to August 2019. Adult patients with a clinician-confirmed diagnosis of SLE based on the 1997 American College of Rheumatology revised criteria or the 2012 Systemic Lupus International Collaborating Clinics Classification Criteria were recruited. SLE disease activity was measured with both SLEDAI-2K and SLE-DAS. Disease-specific quality of life was assessed using the LupusQoL. Results: Of the 333 patients with SLE in this study, 90.4% were female and 40% were between the ages of 20 and 39 years. The median SLEDAI-2K score was 4.00 (interquartile range [IQR] 2.00–7.50) and the median SLE-DAS score was 2.08 (IQR 1.12–8.24) in our patients with SLE. After adjusting for sex and age intervals, both SLEDAI-2k and SLE-DAS were significantly and inversely associated with all eight domains of LupusQoL. The magnitudes of the mean absolute error, root mean square error, Akaike Information Criterion, Bayesian Information Criterion, and coefficient of determination were comparable between SLEDAI-2K and SLE-DAS. Conclusions: There were no clear differences in the use of SLE-DAS over SLEDAI-2K in assessing HRQoL in patients with SLE. We suggest that, in this aspect, both SLEDAI-2K and SLE-DAS are effective tools for measuring disease activity in patients with SLE.

scholarly journals Mannose binding lectin: a biomarker of systemic lupus erythematosus disease activity

2012 ◽  
Vol 14 (5) ◽  
pp. R218 ◽  
Author(s):  
Aditya K Panda ◽  
Jyoti R Parida ◽  
Rina Tripathy ◽  
Sarit S Pattanaik ◽  
Balachandran Ravindran ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Disease Activity ◽  
Lupus Erythematosus ◽  
Mannose Binding Lectin ◽  
Systemic Lupus Erythematosus Disease ◽  
Systemic Lupus ◽  
Mannose Binding ◽  
Binding Lectin
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