Riedel's Thyroiditis and Multifocal Fibrosclerosis are part of the IgG4-related systemic disease spectrum

2010 ◽  
Vol 62 (9) ◽  
pp. 1312-1318 ◽  
Author(s):  
Mollie Dahlgren ◽  
Arezou Khosroshahi ◽  
G. Petur Nielsen ◽  
Vikram Deshpande ◽  
John H. Stone
Keyword(s):  
Systemic Disease ◽  
Riedel’S Thyroiditis ◽  
Multifocal Fibrosclerosis ◽  
Disease Spectrum ◽  
Riedel's Thyroiditis

scholarly journals Riedel’s thyroiditis as a part of the IgG4 systemic disease: A case report

2021 ◽  
Vol 12 ◽  
pp. 1
Author(s):  
Thamyres Marques ◽  
Bárbara Gehrke ◽  
Francinne Machado Ribeiro ◽  
Marise Machado ◽  
Sérgio de Oliveira Romano ◽  
...  
Keyword(s):  
Case Report ◽  
Systemic Disease ◽  
Riedel’S Thyroiditis ◽  
Riedel's Thyroiditis

Riedel’s Thyroiditis and Retroperitoneal Fibrosis in Multifocal Fibrosclerosis

2002 ◽  
Vol 27 (6) ◽  
pp. 413-415 ◽  
Author(s):  
OLIVIER DRIESKENS ◽  
DANIEL BLOCKMANS ◽  
ANNICK VAN DEN BRUEL ◽  
LUC MORTELMANS
Keyword(s):  
Retroperitoneal Fibrosis ◽  
Riedel’S Thyroiditis ◽  
Multifocal Fibrosclerosis ◽  
Riedel's Thyroiditis

Abstract #1024: Riedel’s Thyroiditis in the Spectrum of Igg4-Related Systemic Disease

2015 ◽  
Vol 21 ◽  
pp. 202
Author(s):  
Lily Kwatampora ◽  
Naifa Busaidy ◽  
Michelle Williams ◽  
Aubrey Carhill
Keyword(s):  
Systemic Disease ◽  
Riedel’S Thyroiditis ◽  
Riedel's Thyroiditis

scholarly journals SUN-LB84 Riedel’s Thyroiditis: A Diagnostic and Therapeutic Challenge

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Aleksandra Sliwinska ◽  
Fatima Jalil ◽  
Danielle Millar ◽  
Carl D Malchoff
Keyword(s):  
Side Effects ◽  
Range Of Motion ◽  
Systemic Disease ◽  
Hormone Replacement ◽  
Hashimoto Thyroiditis ◽  
Medical Emergency ◽  
Riedel’S Thyroiditis ◽  
History Of ◽  
Clinical Awareness ◽  
Riedel's Thyroiditis

Abstract Background: Riedel’s thyroiditis is a rare thyroid pathology which presents a challenge for clinicians to diagnose and treat. Etiology remains largely unknown, although data suggests an association with Hashimoto thyroiditis, systemic fibrosis, and IgG-4 related systemic disease. Presentation of Riedel’s thyroiditis can mimic malignant thyroid neoplasm, lymphoma, or a fibrous variant of Hashimoto thyroiditis. Due to its rarity, there is no consensus on the treatment. Clinical case: A 36-year old woman presented with a two-month history of gradually progressing neck swelling. She developed associated neck pain, decreased range of motion, hoarseness, and dysphagia, without difficulty breathing. One year prior to presentation, she had been diagnosed with hypothyroidism. She did not have a family or personal history of thyroid malignancy, however, she lived near Chernobyl during her childhood. On exam, the anterior and lateral neck was hard and enlarged, but nontender. The neck range of motion was diminished. The initial ultrasound of the thyroid demonstrated asymmetrically enlarged heterogenous diffusely nodular right thyroid and isthmus measuring 1.9cm. A CT of the chest with contrast showed diffusely enlarged thyroid extending superiorly beyond the image with mild tracheal displacement. Initial laboratory results included TSH of 17.40 uU/ml (ref: 0.35-4.94 uU/ml), free T4 of 1.06 ng/dl (ref: 0.61-1.82 ng/dl). She had a significantly increased thyroid autoantibodies (Anti-TPO >700 IU/ml with ref: 0.0-9.0 IU/ml, Anti-TG >2000 IU/ml with ref: 0.0-4.0 IU/ml). PTH and calcium were normal, and calcitonin was low. In the interim, the patient was evaluated by ENT without evidence of airway compromise. She underwent a core biopsy of the right thyroid lobe which demonstrated dense fibrous connective tissue mixed with mature lymphocytes. Pathology and immunostaining results were suggestive of Riedel’s thyroiditis. The patient was started on prednisone 60mg daily, which she tolerated for 6 weeks. Due to side effects, prednisone dose was titrated down and tamoxifen was added. Over the following 6 months, compressive symptoms resolved, and the ultrasound showed a significant decrease in the thyroid size. TSH normalized with thyroid hormone replacement. To date, she is asymptomatic and continues on tamoxifen and low dose prednisone without evidence of progression. Conclusion: Riedel’s thyroiditis is a rare condition that can progress into a medical emergency and should be suspected in patients presenting with a thyroid mass. Clinical awareness of Riedel’s symptomatology and laboratory findings should enhance our ability to distinguish and make the diagnosis. Instituting effective treatment that results in the improvement of symptoms and reduction in thyroid size can be challenging due to possible poor response or development of side effects.

MR findings with dynamic evaluation in Riedel's thyroiditis

2002 ◽  
Vol 26 (2) ◽  
pp. 89-91 ◽  
Author(s):  
Naoya Takahashi ◽  
Kouichirou Okamoto ◽  
Kunio Sakai ◽  
Masahiro Kawana ◽  
Motoko Shimada-Hiratsuka
Keyword(s):  
Riedel’S Thyroiditis ◽  
Dynamic Evaluation ◽  
Riedel's Thyroiditis

Riedel’s thyroiditis — Case report and literature review

1994 ◽  
Vol 163 (4) ◽  
pp. 176-177 ◽  
Author(s):  
O. H. Brady ◽  
D. J. Hehir ◽  
S. J. Heffernan
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Riedel’S Thyroiditis ◽  
Riedel's Thyroiditis

scholarly journals Riedel’s thyroiditis associated with mediastinal and retroperitoneal fibrosis

2012 ◽  
Vol 2 (2) ◽  
pp. 200-202
Author(s):  
Said Azzoug ◽  
Keyword(s):  
Retroperitoneal Fibrosis ◽  
Riedel’S Thyroiditis ◽  
Riedel's Thyroiditis

Résumé : La thyroïdite de Riedel est une pathologie fibrosante rare qui s’associe parfois à d’autres pathologies fibrosantes comme rapporté dans l’observation qui suit. Observation : Mme B.F consulte à l’âge de 44 ans pour un goitre de consistance dure pierreuse suspecte ; l’échographie cervicale retrouve un goitre nodulaire calcifié suspect avec des adénopathies satellites, la cytoponction retrouva une hyperplasie lymphoréticulaire non spécifique. La patiente a été opérée retrouvant une thyroïde infiltrant les muscles préthyroïdiens ; les biopsies avec l’étude histologique étaient en faveur d’une thyroïdite de Riedel, la patiente développa par la suite une hypothyroïdie qui fut substituée. Six années plus tard, la patiente développa une toux et un syndrome cave supérieur, le scanner thoracique retrouva un aspect de fibrose médiastinale, la patiente a été mise sous corticoïdes avec une bonne évolution clinique et une stabilisation des lésions sur le plan radiologique. Par la suite, après plusieurs années et suite à des douleurs lombaires droites l’IRM abdominale retrouva une fibrose rétropéritonéale engainant l’uretère droit. Conclusion : La thyroïdite de Riedel s’intègre parfois dans une atteinte fibrosante multi systémique qu’il faudrait rechercher et traiter afin d’améliorer le pronostic du patient.

scholarly journals Riedel's thyroiditis: diagnostic difficulties (clinical case and brief review)

2021 ◽  
pp. 166-171
Author(s):  
A. A. Rybakova ◽  
N. M. Platonova ◽  
T. V. Soldatova ◽  
N. V. Tarbaeva ◽  
T. S. Panevin ◽  
...  
Keyword(s):  
Drug Therapy ◽  
Clinical Case ◽  
Clinical Performance ◽  
Fine Needle Biopsy ◽  
Morphological Description ◽  
Positive Trend ◽  
Riedel’S Thyroiditis ◽  
Compression Syndrome ◽  
Diagnostic Difficulties ◽  
Riedel's Thyroiditis

Riedel's thyroiditis is a rare disease characterized by chronic fibrosis. Clinical performance of this disease is dense stony goiter, which can poorly be displaced during palpation. The overgrowth of the goiter can lead to the development of compression syndrome. To diagnose we need to made fine needle biopsy and made the final diagnose according to its results or according to the morphological description of the postoperative material. An important step in the diagnosis of Riedel's thyroiditis is the determination of serum IgG and IgG4 to exclude an IgG4-associated disease. Treatment of this disease includes drug therapy, which is based on glucocorticosteroids administration or surgical treatment when develops compression syndrome. This article presents a clinical case of a patient with Riedel's thyroiditis; the main complaints were associated with the growth of goiter and the development of compression syndrome. In this regard, patient underwent surgery on the thyroid gland, and after this we get final diagnose. Due to feeling unwell, drug therapy with glucocorticosteroids was prescribed, against the background of which we noted a positive trend.

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