scholarly journals GLP‐1 improves neuropathology after murine cold lesion brain trauma

2014 ◽  
Vol 1 (9) ◽  
pp. 721-732 ◽  
Author(s):  
Brian DellaValle ◽  
Casper Hempel ◽  
Flemming Fryd Johansen ◽  
Jørgen Anders Lindholm Kurtzhals
Keyword(s):  
Brain Trauma ◽  
Cold Lesion

Multicenter Trials for Brain Trauma Questioned

2005 ◽  
Vol 33 (7) ◽  
pp. 50
Author(s):  
JANE SALODOF MACNEIL
Keyword(s):  
Brain Trauma ◽  
Multicenter Trials

The Neuropathological Features of Fatal Pediatric Brain Trauma

2012 ◽  
Vol 2 (1) ◽  
pp. 36-41 ◽  
Author(s):  
Colin Smith ◽  
Milly Lo
Keyword(s):  
Brain Trauma ◽  
Pediatric Brain

scholarly journals Mismatch between Tissue Partial Oxygen Pressure and Near-Infrared Spectroscopy Neuromonitoring of Tissue Respiration in Acute Brain Trauma: The Rationale for Implementing a Multimodal Monitoring Strategy

2021 ◽  
Vol 22 (3) ◽  
pp. 1122
Author(s):  
Mario Forcione ◽  
Mario Ganau ◽  
Lara Prisco ◽  
Antonio Maria Chiarelli ◽  
Andrea Bellelli ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Oxygen Pressure ◽  
Near Infrared ◽  
Optical Signal ◽  
Brain Trauma ◽  
Partial Oxygen Pressure ◽  
Tissue Respiration ◽  
The Brain ◽  
Partial Oxygen

The brain tissue partial oxygen pressure (PbtO2) and near-infrared spectroscopy (NIRS) neuromonitoring are frequently compared in the management of acute moderate and severe traumatic brain injury patients; however, the relationship between their respective output parameters flows from the complex pathogenesis of tissue respiration after brain trauma. NIRS neuromonitoring overcomes certain limitations related to the heterogeneity of the pathology across the brain that cannot be adequately addressed by local-sample invasive neuromonitoring (e.g., PbtO2 neuromonitoring, microdialysis), and it allows clinicians to assess parameters that cannot otherwise be scanned. The anatomical co-registration of an NIRS signal with axial imaging (e.g., computerized tomography scan) enhances the optical signal, which can be changed by the anatomy of the lesions and the significance of the radiological assessment. These arguments led us to conclude that rather than aiming to substitute PbtO2 with tissue saturation, multiple types of NIRS should be included via multimodal systemic- and neuro-monitoring, whose values then are incorporated into biosignatures linked to patient status and prognosis. Discussion on the abnormalities in tissue respiration due to brain trauma and how they affect the PbtO2 and NIRS neuromonitoring is given.

scholarly journals Pathologically Entangled: Brain trauma-evoked ROS imbalance disrupts Kir channel function in distant peripheral vessels

Function ◽  
2021 ◽  
Author(s):  
Nick Weir ◽  
Thomas A Longden
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Potassium Channels ◽  
Vascular Function ◽  
Inward Rectifier ◽  
Brain Trauma ◽  
Channel Function ◽  
Inward Rectifier Potassium Channels ◽  
Kir Channel

Abstract A Perspective on "Traumatic Brain Injury Impairs Systemic Vascular Function Through Disruption of Inward-Rectifier Potassium Channels"

scholarly journals Decline in intracellular free Mg2+ is associated with irreversible tissue injury after brain trauma.

1988 ◽  
Vol 263 (2) ◽  
pp. 757-761
Author(s):  
R Vink ◽  
T K McIntosh ◽  
P Demediuk ◽  
M W Weiner ◽  
A I Faden
Keyword(s):  
Tissue Injury ◽  
Brain Trauma
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