scholarly journals Deep brain simulation effects on verbal fluency dissociated by target and active contact location

Author(s):  
Kevin D. John ◽  
Scott A. Wylie ◽  
Benoit M. Dawant ◽  
William J. Rodriguez ◽  
Fenna T. Phibbs ◽  
...  
2013 ◽  
Vol 124 (8) ◽  
pp. e37
Author(s):  
Tsubasa Sada ◽  
Yuka Watanabe ◽  
Madoka Okamura ◽  
Kenichi Hashimoto ◽  
Koichi Hirata

2015 ◽  
Vol 3 (1) ◽  
pp. 48-52
Author(s):  
Vitalii V. Cozac ◽  
Nadine Schwarz ◽  
Habib Bousleiman ◽  
Menorca Chaturvedi ◽  
Michael M. Ehrensperger ◽  
...  

CNS Spectrums ◽  
2017 ◽  
Vol 23 (1) ◽  
pp. 10-23 ◽  
Author(s):  
Ahmed Elgebaly ◽  
Mohamed Elfil ◽  
Attia Attia ◽  
Mayar Magdy ◽  
Ahmed Negida

BackgroundStudies comparing subthalamus (STN) and globus pallidus internus (GPi) deep brain stimulation (DBS) for the management of Parkinson’s disease in terms of neuropsychological performance are scarce and heterogeneous. Therefore, we performed a systematic review and metaanalysis to compare neuropsychological outcomes following STN DBS versus GPi DBS.MethodsA computer literature search of PubMed, the Web of Science, and Cochrane Central was conducted. Records were screened for eligible studies, and data were extracted and synthesized using Review Manager (v. 5.3 for Windows).ResultsSeven studies were included in the qualitative synthesis. Of them, four randomized controlled trials (n=345 patients) were pooled in the metaanalysis models. The standardized mean difference (SMD) of change in the Stroop color-naming test favored the GPi DBS group (SMD=–0.31,p=0.009). However, other neuropsychological outcomes did not favor either of the two groups (Stroop word-reading:SMD=–0.21,p=0.08; the Wechsler Adult Intelligence Scale (WAIS) digits forward:SMD=0.08,p=0.47; Trail Making Test Part A:SMD=–0.05,p=0.65; WAIS–R digit symbol:SMD=–0.16,p=0.29; Trail Making Test Part B:SMD=–0.14,p=0.23; Stroop color–word interference:SMD=–0.16,p=0.18; phonemic verbal fluency: bilateral DBSSMD=–0.04,p=0.73, and unilateral DBSSMD=–0.05,p=0.83; semantic verbal fluency: bilateral DBSSMD=–0.09,p=0.37, and unilateral DBSSMD=–0.29,p=0.22; Boston Naming Test:SMD=–0.11,p=0.33; Beck Depression Inventory: bilateral DBSSMD=0.15,p=0.31, and unilateral DBSSMD=0.36,p=0.11).ConclusionsThere was no statistically significant difference in most of the neuropsychological outcomes. The present evidence does not favor any of the targets in terms of neuropsychological performance.


2014 ◽  
Vol 18 (S 01) ◽  
Author(s):  
Bárbara Beber ◽  
Aline Cruz ◽  
Carlos Rieder ◽  
Marcia Chaves

2015 ◽  
Vol 5 (1) ◽  
pp. 95-104 ◽  
Author(s):  
Floriane Le Goff ◽  
Stéphane Derrey ◽  
Romain Lefaucheur ◽  
Alaina Borden ◽  
Damien Fetter ◽  
...  

2013 ◽  
Vol 91 (1) ◽  
pp. 24-29 ◽  
Author(s):  
Anders Fytagoridis ◽  
Rickard L. Sjöberg ◽  
Mattias Åström ◽  
Anna Fredricks ◽  
Lars Nyberg ◽  
...  

2014 ◽  
Vol 7 (3) ◽  
pp. 359-364 ◽  
Author(s):  
David J. Pedrosa ◽  
Michelle Auth ◽  
K. Amande M. Pauls ◽  
Matthias Runge ◽  
Mohammad Maarouf ◽  
...  

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Valéria de Carvalho Fagundes ◽  
Carlos R. M. Rieder ◽  
Aline Nunes da Cruz ◽  
Bárbara Costa Beber ◽  
Mirna Wetters Portuguez

Introduction.Deep brain stimulation of the subthalamic nucleus (STN-DBS) in Parkinson’s disease (PD) has been linked to a decline in verbal fluency. The decline can be attributed to surgical effects, but the relative contributions of the stimulation parameters are not well understood. This study aimed to investigate the impact of the frequency of STN-DBS on the performance of verbal fluency tasks in patients with PD.Methods.Twenty individuals with PD who received bilateral STN-DBS were evaluated. Their performances of verbal fluency tasks (semantic, phonemic, action, and unconstrained fluencies) upon receiving low-frequency (60 Hz) and high-frequency (130 Hz) STN-DBS were assessed.Results.The performances of phonemic and action fluencies were significantly different between low- and high-frequency STN-DBS. Patients showed a decrease in these verbal fluencies for high-frequency STN-DBS.Conclusion.Low-frequency STN-DBS may be less harmful to the verbal fluency of PD patients.


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