scholarly journals Behavioral profile of unruptured intracranial aneurysms: a systematic review

2014 ◽  
Vol 1 (3) ◽  
pp. 220-232 ◽  
Author(s):  
Michael J. Bonares ◽  
A. Leonardo de Oliveira Manoel ◽  
R. Loch Macdonald ◽  
Tom A. Schweizer
Keyword(s):  
Systematic Review ◽  
Intracranial Aneurysms ◽  
Behavioral Profile ◽  
Unruptured Intracranial Aneurysms

scholarly journals P.114 Headache outcomes after treatment of unruptured intracranial aneurysms: systematic review and meta-analysis

2019 ◽  
Vol 46 (s1) ◽  
pp. S43-S44
Author(s):  
C Dandurand ◽  
H Parhar ◽  
F Naji ◽  
S Prakash ◽  
PA Gooderham
Keyword(s):  
Systematic Review ◽  
Intracranial Aneurysm ◽  
Intracranial Aneurysms ◽  
Rating Scale ◽  
Meta Analysis ◽  
Effect Estimate ◽  
Significant Heterogeneity ◽  
Unruptured Intracranial Aneurysm ◽  
Standard Mean Difference ◽  
Unruptured Intracranial Aneurysms

Background: Headaches are a major cause of disability and healthcare cost worldwide. When investigating headaches etiology, incidental unruptured intracranial aneurysms are often considered unrelated. We conducted a systematic review and meta-analysis to assess headaches outcomes (severity) after treatment of unruptured intracranial aneurysm. Methods: MEDLINE and EMBASE were systematically reviewed. Results: The data from eligible studies (n=7) was extracted and analyzed. 309 nonduplicated patients provided patient-level data for analysis. All studies used the 10-point numeric rating scale (NRS). 88% of patients were treated with endovascular technique. Overall, the observed effect estimate under a random effects model was found to be a standard mean difference in pre- and post-intervention headache severity of -0.448 (95% CI: -0.566 to -0.329). No significant heterogeneity was noted. No significant publication bias was demonstrated. Conclusions: This is the first and largest systematic review assessing postoperative headache outcomes after treatment of unruptured intracranial aneurysm. A significant reduction in headache intensity after treatment is observed in the current published literature. This study highlights an interesting clinical phenomenon that still warrants scientific effort before it can influence clinical practice. We encourage future study to stratify headache outcomes by aneurysm size, location and treatment modality.

Anesthetic management of unruptured intracranial aneurysms: a qualitative systematic review

2021 ◽  
Author(s):  
Shooka Esmaeeli ◽  
Juan Valencia ◽  
Lauren K. Buhl ◽  
Andres Brenes Bastos ◽  
Sogand Goudarzi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Intracranial Aneurysms ◽  
Anesthetic Management ◽  
Qualitative Systematic Review ◽  
Unruptured Intracranial Aneurysms

Systematic review of treatment for unruptured intracranial aneurysms: clipping vs coiling

2018 ◽  
Author(s):  
Shen Zhe ◽  
Zhao Yachao ◽  
Gu Xuanmin ◽  
Fang Junchao ◽  
Yang Jinsheng ◽  
...  
Keyword(s):  
Systematic Review ◽  
Intracranial Aneurysms ◽  
Unruptured Intracranial Aneurysms

scholarly journals Prevalence, predictors and prognosis of incidental intracranial aneurysms in patients with suspected TIA and minor stroke: a population-based study and systematic review

2020 ◽  
pp. jnnp-2020-324418
Author(s):  
Robert Hurford ◽  
Isabel Taveira ◽  
Wilhelm Kuker ◽  
Peter M Rothwell
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Medical Treatment ◽  
Intracranial Aneurysms ◽  
Population Based ◽  
Minor Stroke ◽  
Unruptured Intracranial Aneurysms ◽  
Symptomatic Carotid Stenosis ◽  
Shared Risk

IntroductionUnruptured intracranial aneurysms (UIAs) are common incidental imaging findings, but there are few data in patients with transient ischaemic attack (TIA)/stroke. The frequency of UIA might be higher due to shared risk factors, but rupture risk might be reduced by intensive secondary prevention. We determined the prevalence and prognosis of UIA in patients with suspected TIA/minor stroke.MethodsAll patients referred to the population-based Oxford Vascular Study (2011–2020) with suspected TIA/minor stroke and non-invasive angiography were included. We determined the prevalence of incidental asymptomatic UIA and the risk of subsequent subarachnoid haemorrhage (SAH) by follow-up on intensive medical treatment, with guideline-based monitoring/management. We also did a systematic review of UIA prevalence/prognosis in cohorts with TIA/stroke.FindingsAmong 2013 eligible patients, 95 (4.7%) had 103 previously unknown asymptomatic UIA. Female sex (OR 2.3, 95% CI 1.5 to 3.7), smoking (2.1, 1.2 to 3.6) and hypertension (1.6, 1.0 to 2.5) were independently predictive of UIA, with a prevalence of 11.1% in those with all three risk factors. During mean follow-up of 4.5 years, only one SAH occurred: 2.3 (95% CI 0.3 to 16.6) per 1000 person-years. We identified 19 studies of UIA in TIA/stroke cohorts (n=12 781), all with either symptomatic carotid stenosis or major acute stroke. The pooled mean UIA prevalence in patients with TIA/stroke was 5.1% (95% CI 4.8 to 5.5) and the incidence of SAH was 4.6 (95% CI 1.9 to 11.0) per 1000 person-years.InterpretationThe 5% prevalence of UIA in patients with confirmed TIA/minor stroke is likely higher than that in the general population. However, the risk of SAH on intensive medical treatment and guideline-based management/monitoring is low.

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