scholarly journals An indirect high iodine ( 131 I) effective dose used for thyroid ablation in patients with thyroid cancer. Is the method of measurement important?

2020 ◽  
Vol 21 (7) ◽  
pp. 173-180
Author(s):  
Issa A. Al‐Shakhrah
Keyword(s):  
Thyroid Cancer ◽  
Effective Dose ◽  
High Iodine ◽  
Thyroid Ablation ◽  
Iodine 131 ◽  
Method Of Measurement

Evaluation of ablation of thyroid remnants with 1850 MBq iodine-131 in 67 patients with thyroid cancer

2019 ◽  
Vol 63 (1) ◽  
Author(s):  
Joji Kawabe ◽  
Shigeaki Higashiyama ◽  
Kohei Kotani ◽  
Atsushi Yoshida ◽  
Naoyoshi Onoda ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Iodine 131

Pancytopenia as a complication of radiotherapy and Iodine 131 treatment in a thyroid cancer

2019 ◽  
Vol 40 (2) ◽  
pp. 89-92 ◽  
Author(s):  
M Herchuelz ◽  
P Bourgeois ◽  
M Aoun
Keyword(s):  
Thyroid Cancer ◽  
Iodine 131

scholarly journals Low urinary iodine is a protective factor of central lymph node metastasis in papillary thyroid cancer: a cross-sectional study

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Ziyang Zeng ◽  
Kang Li ◽  
Xianze Wang ◽  
Siwen Ouyang ◽  
Zimu Zhang ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Protective Factor ◽  
Urinary Iodine ◽  
Iodine Intake ◽  
Clinicopathological Features ◽  
Papillary Thyroid ◽  
Central Lymph Node ◽  
High Iodine ◽  
Central Lymph

Abstract Background An abrupt increase of thyroid cancer has been witnessed paralleling the supplemented iodine intake in formerly iodine-deficient countries. And increased iodine intake has been linked to the rising incidence rate of papillary thyroid cancer (PTC). However, the correlation between iodine and clinicopathological features of PTC has not been well-characterized. This study aimed to investigate the associations between iodine intake and the clinicopathological features of PTC patients. Methods Three hundred and fifty-nine PTC patients who received surgical treatment in Peking Union Medical College Hospital from May 2015 to November 2020 were retrospectively reviewed. The associations between urinary iodine (UI), urinary iodine/creatinine ratio (UI/U-Cr), and the clinicopathological features of PTC were analyzed. Univariate and multivariate analysis were performed to investigate the relationship between UI level and central lymph node metastasis (CLNM). Results There were no significant differences in UI in different groups according to the variables studied, except that patients with CLNM had higher UI level than CLNM(−) patients. No associations were found between UI/U-Cr and clinicopathological features except variant subtypes (classic/follicular). After dividing patients into high-iodine group and low-iodine group, more patients were found to have CLNM in the high-iodine group (p = 0.02). In addition, younger age, larger tumor size, and classic variant were positively correlated with CLNM (p < 0.05). Univariate analysis showed that insufficient iodine intake (≤ 99 μg/L) was associated with decreased CLNM risk in PTC. And after defining insufficient iodine intake as ≤ 109 μg/L and above requirements as ≥ 190 μg/L, multivariate analysis showed that lower iodine was associated with CLNM in total population of PTC (OR 0.53, 95% CI 0.31–0.91) and in PTC < 1 cm (papillary thyroid microcarcinoma, PTMC) (OR 0.43, 95% CI 0.21–0.87). Conclusions Low iodine was a protective factor for CLNM in papillary thyroid cancer, particularly in those < 1 cm. These results indicated that iodine may not only be an initiator of tumorigenesis, but also a promoter of the development of PTC.

Diagnostic and therapeutic applications of radiopharmaceutical agents: The medical use of radioactive iodine (I-131) therapy for hyperthyroidism treatments.

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Hasnae WATLA ◽  
Mohamed LAHKIM ◽  
Mohamed Amine CHAD
Keyword(s):  
Nuclear Medicine ◽  
Effective Dose ◽  
Radioactive Iodine ◽  
Minimum Effective Dose ◽  
Therapeutic Aspect ◽  
Therapeutic Applications ◽  
Medical Centers ◽  
Iodine 131 ◽  
Radiopharmaceutical Agents

The treatment of hyperthyroidism with iodine-131 has been recognized on nuclear medicine as simple, effective and inexpensive, this kind of radiopharmaceutical is chosen by the majority of medical centers by administering a minimum effective dose enabling euthyroidism to be easily compensated as quickly as possible while avoiding radiation problems. In this mini_review, we are going to explain the diagnostic and therapeutic aspect of radiopharmaceuticals by taking an example of radioiodine I-131 and its role on hyperthyroidism treatment .

scholarly journals Thyroglobulin titration and hazard components at follow-up Patients with thyroid cancer

2021 ◽  
Vol 2114 (1) ◽  
pp. 012016
Author(s):  
Aqeel Maryoosh Jary ◽  
Sadeq Naeem Atiyah ◽  
Nazar Ali Abbood ◽  
M. W. Alhamd
Keyword(s):  
Thyroid Cancer ◽  
Globulin Level ◽  
Iodine 131 ◽  
Total Body ◽  
Hazard Components

Abstract The comes about of the total body scintigraphy filter with iodine-131 and the comes about of thyroid globulin titration were surveyed in 90 patients with separated thyroid cancer and with their follow-up after treatment. Amid the follow-up, backslides were watched in 12 cases, 8 cases (3 cases: ordinary thyroid globulin, 5 cases: tall thyroid gobolin) analyzed by scintigraphy filter and 5 cases with tall thyroid globulin level and the scintigraphy scan negative and backslide was analyzed with the assistance of radiography or ultrasound. Of the 24 cases who gotten sparkle filters demonstrating doubt of repeat, 6 cases were repetitive, whereas as it were 2 of the 63 routinely performed cases were found. It was watched that 10 of the 12 patients who had a backslide were from the tall hazard gather. When considering the typical upper constrain for thyroglobulin 10ng/ml, 3 untrue negative cases were found among patients with backslides, and the number diminished to 1 on the off chance that the upper restrain was considered 5ng/ml. In.

scholarly journals MONTE CARLO SIMULATION IN INTERNAL RADIOTHERAPY OF THYROID CANCER

2020 ◽  
Vol 3 (9) ◽  
pp. 16-24 ◽  
Author(s):  
Hammam Oktajianto ◽  
Evi Setiawati
Keyword(s):  
Monte Carlo Simulation ◽  
Monte Carlo ◽  
Thyroid Cancer ◽  
Monte Carlo Method ◽  
Effective Dose ◽  
Radiation Effect ◽  
Cervical Vertebrae ◽  
Absorbed Dose ◽  
Particle Track ◽  
Internal Radiotherapy

Thyroid radiotherapy is a cancer therapy that is treated by giving radioactive I-131 in Thyroid gland. This cancer is at the ninth from ten of common malignant cancer. A man has higher risk to get Thyroid cancer than a woman has. This organ is lain near human neck. This research aim was to simulate particle track of radiation I-131 and determine an absorbed dose and effective dose in Thyroid and other organs around Thyroid such as Brain, Lung and Cervical vertebrae. The simulation and calculation used Monte Carlo method operated by MCNPX software. Geometry of Thyroid and other organs used ORNL MIRD phantom geometry. From the results, it shown that particle track of radiation was distributed at Thyroid while several particles radiated other organs. The absorbed dose in Thyroid and other organs increased every rising activity of I-131 used, but the absorbed dose in other organs was less than in Thyroid. Radiation effect for damage cancer in Thyroid was shown by an effective dose which it increased every rising activity of I-131 used and the maximum effective dose was at 200 mCi activity of I-131. Although the effective dose in Thyroid increased, the effective dose in other organs like Brain, Lung and Cervical vertebrae was still less than in Thyroid so that the use of I-131 each activity did not really influence other organs around Thyroid.  

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