scholarly journals Validation of MLC-based linac radiosurgery for trigeminal neuralgia

2018 ◽  
Vol 19 (4) ◽  
pp. 214-221 ◽  
Author(s):  
M. Tynan R. Stevens ◽  
Eric C. Lobb ◽  
Kamil M. Yenice
Keyword(s):  
Trigeminal Neuralgia ◽  
Linac Radiosurgery

Dedicated linear accelerator radiosurgery for the treatment of trigeminal neuralgia

2003 ◽  
Vol 99 (3) ◽  
pp. 511-516 ◽  
Author(s):  
Zachary A. Smith ◽  
Antonio A. F. De Salles ◽  
Leonardo Frighetto ◽  
Bryan Goss ◽  
Steve P. Lee ◽  
...  
Keyword(s):  
Pain Relief ◽  
Trigeminal Neuralgia ◽  
Linear Accelerator ◽  
Facial Pain ◽  
Content Type ◽  
Excellent Outcome ◽  
Linac Radiosurgery ◽  
Root Entry Zone ◽  
Fine Print

Object. In this study the authors evaluate the efficacy of and complications associated with dedicated linear accelerator (LINAC) radiosurgery for trigeminal neuralgia (TN). Methods. Between August 1995 and February 2001, 60 patients whose median age was 66.1 years (range 45–88 years) were treated with dedicated LINAC radiosurgery for TN. Forty-one patients (68.3%) had essential TN, 12 (20%) had secondary facial pain, and seven (11.7%) had atypical features. Twenty-nine patients (48.3%) had undergone previous surgical procedures. Radiation doses varied between 70 and 90 Gy (mean 83.3 Gy) at the isocenter, with the last 35 patients (58.3%) treated with a 90-Gy dose. A 5-mm collimator was used in 45 patients (75%) and a 7.5-mm collimator in 15 patients (25%). Treatment was focused at the nerve root entry zone. At last follow up (mean follow-up period 23 months, range 2–70 months), 36 (87.8%) of the 41 patients with essential TN had sustained significant pain relief (good plus excellent results). Twenty-three patients (56.1%) were pain free without medication (excellent outcome), 13 (31.7%) had a 50 to 90% reduction in pain with or without medication (good outcome), and five (12.2%) had minor improvement or no relief. Of 12 patients with secondary facial pain, significant relief was sustained in seven patients (58.3%); worse results were found with atypical pain. Fifteen (25%) of the 60 patients experienced new numbness postprocedure; no other significant complications were found. Pain relief was experienced at a mean of 2.7 months (range 0–12 months). Conclusions. Dedicated LINAC radiosurgery is a precise and effective treatment for TN.

Patient Assessment of Outcome After LINAC Radiosurgery for Trigeminal Neuralgia

2007 ◽  
Vol 69 (3) ◽  
pp. S548
Author(s):  
A.L. Stockham ◽  
C. Reddy ◽  
P.W. Hitchon ◽  
T.C. Ryken ◽  
M.C. Smith ◽  
...  
Keyword(s):  
Trigeminal Neuralgia ◽  
Patient Assessment ◽  
Linac Radiosurgery

FMRI activation in spontaneous trigeminal neuralgia attacks

2009 ◽  
Vol 36 (S 02) ◽  
Author(s):  
M Obermann ◽  
D Müller ◽  
E Gizewski ◽  
Z Katsarava ◽  
D Holle
Keyword(s):  
Trigeminal Neuralgia

Gray matter volume reduction reflects chronic pain in trigeminal neuralgia

2012 ◽  
Vol 43 (01) ◽  
Author(s):  
M Obermann ◽  
R Rodriguez-Raecke ◽  
S Nägel ◽  
D Holle ◽  
N Theysohn ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Trigeminal Neuralgia ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Volume Reduction ◽  
Matter Volume
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