Efficient Pulse Sequences for NMR Microscopy

2018 ◽  
pp. 199-235 ◽  
Author(s):  
Jürgen Hennig ◽  
Katharina Göbel-Guéniot ◽  
Linnéa Hesse ◽  
Jochen Leupold
Keyword(s):  
Pulse Sequences ◽  
Nmr Microscopy

Recent progress in NMR microscopy towards cellular imaging

1990 ◽  
Vol 333 (1632) ◽  
pp. 469-475 ◽  
Keyword(s):  
Molecular Diffusion ◽  
Signal To Noise Ratio ◽  
Pulse Sequences ◽  
Cell Lineage ◽  
Experimental System ◽  
Cellular Imaging ◽  
Physical Parameters ◽  
Nmr Microscopy ◽  
Resolution Limits ◽  
Finite Line

Recent advances in NMR microscopy based on fundamental physical parameters and experimental factors are discussed. We consider fundamental resolution limits due to molecular diffusion and the experimental system bandwidth, as well as practical resolution limits arising from poor signal-to-noise ratio due to small imaging voxel size and finite line broadening due to signal attenuation brought about by diffusion. Several microscopic imaging pulse sequences are presented and applied to elucidating cellular imaging problems such as the cell lineage patterns in Xenopus laevis embryos. Experimental results obtained with 7.0 T NMR microscopy system are presented.

An emerging technology: Nuclear magnetic resonance microscopy

1988 ◽  
Vol 46 ◽  
pp. 1000-1001
Author(s):  
M.J. Hennessy ◽  
E. Kwok
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Relaxation Times ◽  
Basic Research ◽  
Local Environment ◽  
Magnetic Resonance Images ◽  
Nmr Microscopy ◽  
Mri Scans ◽  
Temperature Relaxation ◽  
Nuclear Magnetic

Much progress in nuclear magnetic resonance microscope has been made in the last few years as a result of improved instrumentation and techniques being made available through basic research in magnetic resonance imaging (MRI) technologies for medicine. Nuclear magnetic resonance (NMR) was first observed in the hydrogen nucleus in water by Bloch, Purcell and Pound over 40 years ago. Today, in medicine, virtually all commercial MRI scans are made of water bound in tissue. This is also true for NMR microscopy, which has focussed mainly on biological applications. The reason water is the favored molecule for NMR is because water is,the most abundant molecule in biology. It is also the most NMR sensitive having the largest nuclear magnetic moment and having reasonable room temperature relaxation times (from 10 ms to 3 sec). The contrast seen in magnetic resonance images is due mostly to distribution of water relaxation times in sample which are extremely sensitive to the local environment.

Evaluation of pulse sequences used for magnetic resonance sialography

2001 ◽  
Vol 30 (5) ◽  
pp. 276-284 ◽  
Author(s):  
M Sakamoto ◽  
T Sasano ◽  
S Higano ◽  
S Takahashi ◽  
T Nagasaka ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Pulse Sequences ◽  
Magnetic Resonance Sialography

Designing Generators of Poisson Pulse Sequences Based on the Additive Fibonacci Generators

2017 ◽  
Vol 49 (12) ◽  
pp. 1-13 ◽  
Author(s):  
Vladimir N. Maksymovych ◽  
Oleg I. Harasymchuk ◽  
Marya N. Mandrona
Keyword(s):  
Pulse Sequences

Engineering Electronic Structure to Protect Phase Memory in Molecular Qubits by Minimising Orbital Angular Momentum

2018 ◽  
Author(s):  
Ana Maria Ariciu ◽  
David H. Woen ◽  
Daniel N. Huh ◽  
Lydia Nodaraki ◽  
Andreas Kostopoulos ◽  
...  
Keyword(s):  
Electron Spin ◽  
Quantum Coherence ◽  
Quantum Information Processing ◽  
Pulse Sequences ◽  
Grover Algorithm ◽  
Ligand Shell ◽  
Information Strategies ◽  
Spin Qubit ◽  
Molecular Spin ◽  
The Impact

Using electron spins within molecules for quantum information processing (QIP) was first proposed by Leuenberger and Loss (1), who showed how the Grover algorithm could be mapped onto a Mn12 cage (2). Since then several groups have examined two-level (S = ½) molecular spin systems as possible qubits (3-12). There has also been a report of the implementation of the Grover algorithm in a four-level molecular qudit (13). A major challenge is to protect the spin qubit from noise that causes loss of phase information; strategies to minimize the impact of noise on qubits can be categorized as corrective, reductive, or protective. Corrective approaches allow noise and correct for its impact on the qubit using advanced microwave pulse sequences (3). Reductive approaches reduce the noise by minimising the number of nearby nuclear spins (7-11), and increasing the rigidity of molecules to minimise the effect of vibrations (which can cause a fluctuating magnetic field via spin-orbit coupling) (9,11); this is essentially engineering the ligand shell surrounding the electron spin. A protective approach would seek to make the qubit less sensitive to noise: an example of the protective approach is the use of clock transitions to render spin states immune to magnetic fields at first order (12). Here we present a further protective method that would complement reductive and corrective approaches to enhancing quantum coherence in molecular qubits. The target is a molecular spin qubit with an effective 2S ground state: we achieve this with a family of divalent rare-earth molecules that have negligible magnetic anisotropy such that the isotropic nature of the electron spin renders the qubit markedly less sensitive to magnetic noise, allowing coherent spin manipulations even at room temperature. If combined with the other strategies, we believe this could lead to molecular qubits with substantial advantages over competing qubit proposals.<br>

Optimization of Parameters of RF Pulse Sequences for MRI Investigations in the Presence of Magnetic Nanoparticles

2020 ◽  
Vol 65 (9) ◽  
pp. 1416-1420
Author(s):  
Yu. V. Bogachev ◽  
A. V. Nikitina ◽  
V. V. Frolov ◽  
Ya. Yu. Marchenko ◽  
B. P. Nikolaev
Keyword(s):  
Magnetic Nanoparticles ◽  
Pulse Sequences ◽  
Optimization Of Parameters ◽  
Rf Pulse

scholarly journals Arbitrarily Accurate Pulse Sequences for Robust Dynamical Decoupling

2017 ◽  
Vol 118 (13) ◽  
Author(s):  
Genko T. Genov ◽  
Daniel Schraft ◽  
Nikolay V. Vitanov ◽  
Thomas Halfmann
Keyword(s):  
Pulse Sequences ◽  
Dynamical Decoupling

scholarly journals Solid State NMR Spectroscopy a Valuable Technique for Structural Insights of Advanced Thin Film Materials: A Review

Nanomaterials ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1494
Author(s):  
Mustapha El Hariri El Nokab ◽  
Khaled O. Sebakhy
Keyword(s):  
Thin Film ◽  
Thin Films ◽  
Solid State ◽  
Solid State Nmr ◽  
Pulse Sequences ◽  
3D Structure ◽  
Spectroscopic Techniques ◽  
Film Research ◽  
Versatile Technique ◽  
Work Done

Solid-state NMR has proven to be a versatile technique for studying the chemical structure, 3D structure and dynamics of all sorts of chemical compounds. In nanotechnology and particularly in thin films, the study of chemical modification, molecular packing, end chain motion, distance determination and solvent-matrix interactions is essential for controlling the final product properties and applications. Despite its atomic-level research capabilities and recent technical advancements, solid-state NMR is still lacking behind other spectroscopic techniques in the field of thin films due to the underestimation of NMR capabilities, availability, great variety of nuclei and pulse sequences, lack of sensitivity for quadrupole nuclei and time-consuming experiments. This article will comprehensively and critically review the work done by solid-state NMR on different types of thin films and the most advanced NMR strategies, which are beyond conventional, and the hardware design used to overcome the technical issues in thin-film research.

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