Abnormal Urine Output and Renal Function

2011 ◽  
pp. 143-149
Keyword(s):  
Renal Function ◽  
Urine Output

Rhythmic changes in renal function in the rat

1965 ◽  
Vol 209 (6) ◽  
pp. 1187-1192 ◽  
Author(s):  
George A. Bray
Keyword(s):  
Renal Function ◽  
Cold Exposure ◽  
Sodium Excretion ◽  
Urine Output ◽  
Sodium Intake ◽  
Urine Volume ◽  
Potassium Excretion ◽  
Electrolyte Excretion ◽  
Threefold Increase ◽  
Electrolyte Intake

Cold exposure causes rats to increase their urine output. This increase in urine output was found to occur in 5- to 8-day cycles with peak urine volumes three or more times the volumes prior to exposure to the cold. Cycles in urine volume occurred on a constant electrolyte intake and in animals receiving exogenous Pitressin. The peaks in urine volume were accompanied by a threefold increase in the variability of sodium excretion but not potassium excretion. The increase in urine volume which occurred at the same time in all rats in a group began at night and continued through the following day. These data have been discussed in the light of a possible mechanism controlling sodium intake with water intake and electrolyte excretion.

scholarly journals Acute Renal Failure and Jaundice without Methemoglobinemia in a Patient with Phenazopyridine Overdose: Case Report and Review of the Literature

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Ian Holmes ◽  
Nathaniel Berman ◽  
Vinicius Domingues
Keyword(s):  
United States ◽  
Renal Failure ◽  
Renal Function ◽  
Acute Renal Failure ◽  
Case Report ◽  
Hemolytic Anemia ◽  
Normal Renal Function ◽  
Urine Output ◽  
The United States ◽  
Review Of The Literature

Phenazopyridine is a commonly used urinary analgesic available throughout the United States. Ingestion of large quantities can lead to methemoglobinemia, hemolytic anemia, jaundice, and acute renal failure. We report a case of a 78-year-old male with previously normal renal function who developed acute renal failure and jaundice without methemoglobinemia or hyperbilirubinemia after taking nearly 8 g of phenazopyridine over the course of 4 days. Initially presenting with oliguria, the urine output began to increase by day 2 of his admission, and the creatinine peaked 11 days after he began taking phenazopyridine, and he was discharged safely soon after. To our knowledge, this is the first such case of renal failure and jaundice without methemoglobinemia or hemolytic anemia in an adult patient with normal renal function.

scholarly journals Micophenolat Mofetil Versus Azathioprine: Effects on Renal Graft Function in Early Posttransplant Period

2009 ◽  
Vol 9 (2) ◽  
pp. 156-160
Author(s):  
Farid Ljuca ◽  
Semir Imamović ◽  
Dešo Mešić ◽  
Šefik Hasukić ◽  
Safet Omerović ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Renal Function ◽  
Urine Output ◽  
Filtration Rate ◽  
Graft Function ◽  
Low Doses ◽  
Post Transplant ◽  
Renal Graft ◽  
Clinical Transplantation ◽  
Clinical Centre

All conventional immunosuppressive tree drugs-protocols are based on Cyclosporine; consisting of low doses of Cyclosporine (CsA), Azathioprine (AZA) or Mycophenolate Mofetil (MMF) and Prednisolone, AZA has been used in clinical transplantation for more than 30 years and was the first immunosuppres-sive agent to achieve widespread use in organ transplantation. MMF was introduced in clinical practice in 1995 after several clinical trials proved that it was more efficient than AZA for prevention of acute rejection episodes. Our aim was to evaluate influence of AZA and MMF on renal graft function in early post-transplant stage. Study recruited 74 patients who underwent kidney transplantation in University Clinical Centre Tuzla. All patients received CsA and corticosteroid-based immunosuppression, as a part of triple immunosuppressive regiment, 40 patients received AZA and 34 MMF. In order to assess renal graft function, following parameters were evaluated: glomerular filtration rate GFR (ml/min) creatinine clearance (CrCl) (ml/min), 24 h urine output (ml/day), and from the serum potassium, sodium, urea and creatinine (mmol/dm3). Significantly higher average values of 24 hour urine output were recorded during first seven postoperative days in patients receiving MMF compared to those treated with AZA. Serum creatinine values showed statistically significant decrease, starting with the second postoperative day, in MMF vs. AZA group (168,7±70,5 vs. 119,9±42,6; p<0,0007). GFR was significantly higher in MMF compared to the AZA group of patients. On the first post-transplant day CrCl was higher in AZA group (24,3±10 vs. 17,5±7,3; p=0,01), next six days situation is reversed CrCl is significantly higher in the MMF group (43,7±15 vs. 53, 4±22, 8 p=0,006). MMF vs. AZA therapy was associated with protective effect against worsening of renal function in first seven post-transplant days.

Measuring intraabdominal pressure

1990 ◽  
Vol 10 (3) ◽  
pp. 54-66 ◽  
Author(s):  
D Lameier ◽  
D NeCamp
Keyword(s):  
Renal Function ◽  
Critical Care ◽  
Causal Relationship ◽  
Urine Output ◽  
Clinical Parameter ◽  
Critical Care Nurses ◽  
Intraabdominal Pressure ◽  
Formal Study ◽  
Time Relationship ◽  
The Future

This article is intended to help nurses understand the physiologic rationale for the measurement of IAP. We were able to see a time relationship between increasing IAP and decreasing urine output in our patients. When measures were taken to reduce IAP, urine output improved. No causal relationship is implied because no formal study was done and many other factors may have influenced the IAP measurement and the renal function of these patients. Critical care nurses may be called upon to measure this clinical parameter more frequently in the future. Our experience with IAP may help other critical care nurses when they begin to measure the IAP of their patients.

EXTRACORPOREAL DETOXIFICATION METHODS IN THE PATHOGENETIC THERAPY OF OBSTETRIC SEPSIS

Vestnik ◽  
2021 ◽  
pp. 147-150
Author(s):  
С.Н. Ералина ◽  
Е.Л. Исмаилов ◽  
М.Е. Рамазанов ◽  
Б.Ж. Аджибаев ◽  
Д.К. Сейтпанов ◽  
...  
Keyword(s):  
Septic Shock ◽  
Renal Function ◽  
Urine Output ◽  
Clinical Signs ◽  
Complex Treatment ◽  
Rapid Elimination ◽  
Pathogenetic Therapy ◽  
Osmotic Balance ◽  
Sepsis And Septic Shock

Раннее включение НВВГФ в комплексном лечении сепсиса и септического шока приводит к снижению клинических признаков эндотоксикоза, стабилизации гемодинамики в более ранние сроки, что связано с быстрой элиминацией цитокинов, коррекцией осмотического равновесия, увеличением диуреза, благодаря более раннему протезированию гомеостатической функции почек. Early inclusion of NVHF in the complex treatment of sepsis and septic shock leads to a decrease in clinical signs of endotoxicosis, stabilization of hemodynamics at an earlier time, which is associated with rapid elimination of cytokines, correction of osmotic balance, increased urine output due to earlier prosthetics of homeostatic renal function.

scholarly journals Short-Time Intermittent Preexposure of Living Human Donors to Hyperoxia Improves Renal Function in Early Posttransplant Period: A Double-Blind Randomized Clinical Trial

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Kamran Montazeri ◽  
Mohammadali Vakily ◽  
Azim Honarmand ◽  
Parviz Kashefi ◽  
Mohammadreza Safavi ◽  
...  
Keyword(s):  
Renal Function ◽  
Kidney Transplantation ◽  
Hospital Stay ◽  
Urine Output ◽  
Human Study ◽  
Kidney Donor ◽  
Living Kidney Donor ◽  
Duration Of Hospital Stay ◽  
Group I ◽  
Group Ii

The purpose of this human study was to investigate the effect of oxygen pretreatment in living kidney donors on early renal function of transplanted kidney. Sixty living kidney donor individuals were assigned to receive either 8–10 L/min oxygen (Group I) by a non-rebreather mask with reservoir bag intermittently for one hour at four times (20, 16, 12, and 1 hours before transplantation) or air (Group II). After kidney transplantation, urine output, blood urea nitrogen (BUN), serum creatinine, need to additional diuretics (NTADs) in the first 24 hours after transplantation, delayed graft function (DGF), the creatinine clearance (CrCL) on 10th day, and duration of hospital stay from the first posttransplant day till normalization of renal function was recorded and compared in two groups. Mean CrCL in posttransplant day 10, NTAD after 24 hours of transplantation, and urine output during 6 hours after operation were significantly better in Group I compared with Group II (). Also, DGF during the first week after operation and duration of hospital stay was less in Group I compared with Group II. Intermittent exposure of human living kidney donor to hyperoxic environment may improve renal function following kidney transplantation.

scholarly journals A Case of Upper Ureter Rupture With Acute Kidney Injury

2018 ◽  
Vol 11 ◽  
pp. 117954761878513
Author(s):  
Yuko Mutsuyoshi ◽  
Shohei Kaneko ◽  
Saori Minato ◽  
Katsunori Yanai ◽  
Hiroki Ishii ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Renal Function ◽  
Renal Injury ◽  
Urine Output ◽  
Urinary Catheter ◽  
Kidney Injury ◽  
Benign Prostatic Hypertrophy ◽  
Acute Renal Injury ◽  
Surgical Operation ◽  
Normal Range

We herein report a case of ureter rupture with severe oliguric acute renal injury due to benign prostatic hypertrophy. After insertion of an indwelling urinary catheter, the patient’s urine output immediately increased. His symptoms and renal function also rapidly improved to the normal range without a surgical operation. Clinicians should note this complication in patients with oliguria.

RENAL FUNCTION AND CLINICAL PROFILE IN CHILDREN WITH CONGENITAL HEART DISEASE – AN OBSERVATIONAL STUDY FROM TERTIARY CARE HOSPITAL IN CENTRAL INDIA.

2021 ◽  
pp. 8-10
Author(s):  
Tulsi Devi Dhurvey ◽  
Ghanshyam Das ◽  
Ajay Gaur ◽  
Satvik Bansal
Keyword(s):  
Socioeconomic Status ◽  
Congenital Heart Disease ◽  
Renal Function ◽  
Heart Disease ◽  
Serum Creatinine ◽  
Serum Creatinine Level ◽  
Creatinine Level ◽  
Urine Output ◽  
Congenital Heart ◽  
Cleft Lip

Purpose: To evaluate the renal function and clinical prole in children with congenital heart disease. Method: After taking informed consent from the parents of 118 children aged 1 month to 14 years were recruited in study. Anthropometry and vitals were noted. Complete physical examination and USG abdomen done to identify any other associated congenital anomaly. Laboratory evaluation of serum creatinine was done on day 1 and day 5. 24 hours urine output was strictly measured till day 5 of admission. Result: The maximum number of cases belonged to age group 1-6 month. Male children were affected more than females (1.5:1) and majority of the children belong to family of lower middle and lower socioeconomic status. Most of the children belong to rural area. Among syndromic features, microcephaly and cleft lip and cleft palate were most frequently observed. Most of the cases had weight /height <-3SD. There was no major signicant difference in mean value of urine output and serum creatinine level in different age groups and in between cyanotic and acyanotic group. Conclusion: Congenital heart disease forms a significant diagnosis in hospitalized children. Larger studies are needed to evaluate newer associations (like male gender and low socioeconomic status). Microcephaly and cleft lip/palate were most observed associated syndromic features. No signicant effect was observed on the mean urine output and serum creatinine level in children with congenital heart disease.

scholarly journals Prolonged warm ischemia time leads to severe renal dysfunction of donation-after-cardiac death kidney grafts

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Peter Urbanellis ◽  
Laura Mazilescu ◽  
Dagmar Kollmann ◽  
Ivan Linares-Cervantes ◽  
J. Moritz Kaths ◽  
...  
Keyword(s):  
Renal Function ◽  
Serum Creatinine ◽  
Renal Dysfunction ◽  
Serum Potassium ◽  
Urine Output ◽  
Cardiac Death ◽  
Elevated Serum ◽  
Graft Function ◽  
Donation After Cardiac Death ◽  
Large Animal

AbstractKidney transplantation with grafts procured after donation-after-cardiac death (DCD) has led to an increase in incidence of delayed graft function (DGF). It is thought that the warm ischemic (WI) insult encountered during DCD procurement is the cause of this finding, although few studies have been designed to definitely demonstrate this causation in a transplantation setting. Here, we use a large animal renal transplantation model to study the effects of prolonged WI during procurement on post-transplantation renal function. Kidneys from 30 kg-Yorkshire pigs were procured following increasing WI times of 0 min (Heart-Beating Donor), 30 min, 60 min, 90 min, and 120 min (n = 3–6 per group) to mimic DCD. Following 8 h of static cold storage and autotransplantation, animals were followed for 7-days. Significant renal dysfunction (SRD), resembling clinical DGF, was defined as the development of oliguria < 500 mL in 24 h from POD3-4 along with POD4 serum potassium > 6.0 mmol/L. Increasing WI times resulted in incremental elevation of post-operative serum creatinine that peaked later. DCD120min grafts had the highest and latest elevation of serum creatinine compared to all groups (POD5: 19.0 ± 1.1 mg/dL, p < 0.05). All surviving animals in this group had POD4 24 h urine output < 500 cc (mean 235 ± 172 mL) and elevated serum potassium (7.2 ± 1.1 mmol/L). Only animals in the DCD120min group fulfilled our criteria of SRD (p = 0.003), and their renal function improved by POD7 with 24 h urine output > 500 mL and POD7 serum potassium < 6.0 mmol/L distinguishing this state from primary non-function. In a transplantation survival model, this work demonstrates that prolonging WI time similar to that which occurs in DCD conditions contributes to the development of SRD that resembles clinical DGF.

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